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Kocevska, D. (author), Lysen, T.S. (author), Dotinga, A. (author), Koopman-Verhoeff, M.E. (author), Luijk, M.P.C.M. (author), Antypa, N. (author), Biermasz, N.R. (author), Blokstra, A. (author), Brug, J. (author), Burk, W.J. (author), Comijs, H.C. (author), Corpeleijn, E. (author), Dashti, H.S. (author), de Bruin, E.J. (author), de Graaf, R. (author), Derks, I.P.M. (author), Dewald-Kaufmann, J.F. (author), Elders, P.J.M. (author), Gemke, R.J.B.J. (author), Grievink, L. (author), Hale, L. (author), Hartman, C.A. (author), Heijnen, C.J. (author), Huisman, M. (author), Huss, A. (author), Ikram, M.A. (author), Jones, S.E. (author), Klein Velderman, M. (author), Koning, M. (author), Meijer, A.M. (author), Meijer, K. (author), Noordam, R. (author), Oldehinkel, A.J. (author), Groeniger, J.O. (author), Penninx, B.W.J.H. (author), Picavet, H.S.J. (author), Pieters, S. (author), Reijneveld, S.A. (author), Reitz, E. (author), Renders, C.M. (author), Rodenburg, G. (author), Rutters, F. (author), Smith, M.C. (author), Singh, A.S. (author), Snijder, M.B. (author), Stronks, K. (author), ten Have, M, (author), Twisk, J.W.R. (author), van de Mheen, D. (author), van der Ende, J. (author), van der Heijden, K.B. (author), van der Velden, P.G. (author), van Lenthe, F.J. (author), van Litsenburg, R.R.L (author), van Oostrom, S.H. (author), van Schalkwijk, F.J. (author), Sheehan, CM, (author), Verheij, RA, (author), Verhulst, F.C. (author), Vermeulen, M.C.M. (author), Vermeulen, R.C.H. (author), Verschuren, W.M.M. (author), Vrijkotte, T.G.M. (author), Wijga, A.H. (author), Willemen, A.M. (author), ter Wolbeek, M. (author), Wood, A.R. (author), Xerxa, Y. (author), Bramer, W.M. (author), Franco, O.H. (author), Luik, A.I. (author), van Someren, E.J.W. (author), Tiemeier, H. (author)
We aimed to obtain reliable reference charts for sleep duration, estimate the prevalence of sleep complaints across the lifespan and identify risk indicators of poor sleep. Studies were identified through systematic literature search in Embase, Medline and Web of Science (9 August 2019) and through personal contacts. Eligible studies had to be...
article 2021
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Versluis, A. (author), van Os-Medendorp, H. (author), Blom, W.M. (author), Michelsen-Huisman, A.D. (author), Castenmiller, J.J.M. (author), Noteborn, H.P.J.M. (author), Houben, G.F. (author), Knulst, A.C. (author)
Background: Cofactors, such as physical exercise and alcohol intake, might be associated with the severity or occurrence of food allergic reactions. Objective: To gain insight into the frequency of presence of potential cofactors in accidental food allergic reactions in adults and to what extent these factors influence the severity and...
article 2019
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Kartaram, S. (author), Mensink, M. (author), Teunis, M. (author), Schoen, E. (author), Witte, G. (author), Janssen Duijghuijsen, L. (author), Verschuren, M. (author), Mohrmann, K. (author), M'Rabet, L. (author), Knipping, K. (author), Wittink, H. (author), van Helvoort, A. (author), Garssen, J. (author), Witkamp, R. (author), Pieters, R. (author), van Norren, K. (author)
Background & aims: Plasma citrulline concentration is considered to be a marker for enterocyte metabolic mass and to reflect its reduction as may occur during intestinal dysfunction. Strenuous exercise can act as a stressor to induce small intestinal injury. Our previous studies suggest that this comprises the intestinal ability to produce...
article 2019
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Brenninkmeijer, V. (author), Lagerveld, S. (author), Blonk, R.W.B. (author), Schaufeli, W.B. (author), Wijngaards-de Meij, L.D.N.V. (author)
Purpose This study examined who benefits most from a cognitive behavioural therapy (CBT)-based intervention that aims to enhance return to work (RTW) among employees who are absent due to common mental disorders (CMDs) (e.g., depression, anxiety, or adjustment disorder). We researched the influence of baseline work-related self-efficacy and...
article 2019
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Bogerd, C.P. (author), Velt, K.B. (author), Annaheim, S. (author), Bongers, C.C.W.G. (author), Eijsvogels, T.M.H. (author), Daanen, H.A.M. (author)
OBJECTIVE: The discomfort caused by rectal probes and esophageal probes for the estimation of body core temperature has triggered the development of gastrointestinal (GI) capsules that are easily accepted by athletes and workers due to their non-invasive characteristics. We compare two new GI capsule devices with rectal temperature during cycle...
article 2018
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de Ligt, R. (author), van Duijn, E. (author), Grossouw, D. (author), Bosgra, S. (author), Burggraaf, J. (author), Windhorst, A. (author), Peeters, P.A.M. (author), van der Luijt, G.A. (author), Alexander-White, C. (author), Vaes, W.H.J. (author)
A clinical pharmacokinetic study was performed in 12 healthy women to evaluate systemic exposure to aluminum following topical application of a representative antiperspirant formulation under real-life use conditions. A simple roll-on formulation containing an extremely rare isotope of aluminum (26 Al) chlorohydrate (ACH) was prepared to...
article 2018
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Michelsen-Huisman, A.D. (author), van Os-Medendorp, H. (author), Blom, W.M. (author), Versluis, A. (author), Castenmiller, J.J.M. (author), Noteborn, H.P.J.M. (author), Kruizinga, A.G. (author), Houben, G.F. (author), Knulst, A.C. (author)
[No abstract available]
article 2018
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Eijsink, A.M. (author), Schipper, G. (author), Vermaire, J.H. (author)
Background People with intellectual disabilities have less favourable outcomes in—among others—oral health variables, compared to their peers without intellectual disabilities. Before being able to develop target interventions for caregivers, all their prevailing viewpoints regarding oral hygiene need to be identified. Methods This Q-methodology...
article 2018
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Rowen, D. (author), Mulhem, B. (author), Stevens, K. (author), Vermaire, J.H. (author)
Objective This article presents the development of the Dutch value set for the Child Health Utility 9D, a pediatric preference-based measure of quality of life that can be used to generate quality-adjusted life-years. Methods A large online survey was conducted using a discrete choice experiment including a duration attribute with adult members...
article 2018
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Botschuijver, S. (author), Roeselers, G. (author), Levin, E. (author), Jonkers, D.M. (author), Welting, O. (author), Heinsbroek, S.E.M. (author), de Weerd, H.H. (author), Boekhout, T. (author), Fornai, M. (author), Masclee, A.A. (author), Schuren, F.H.J. (author), de Jonge, W.J. (author), Seppen, J. (author), van den Wijngaard, R.M. (author)
Background & Aims Visceral hypersensitivity is one feature of irritable bowel syndrome (IBS). Bacterial dysbiosis might be involved in the activation of nociceptive sensory pathways, but there have been few studies of the role of the mycobiome (the fungal microbiome) in the development of IBS. We analyzed intestinal mycobiomes of patients with...
article 2017
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Ly, V. (author), Roijendijk, L.L.M. (author), Hazebroek, H. (author), Tonnaer, C. (author), Hagenaars, M.A. (author)
Freezing is a defensive response to acute stress that is associated with coping and alterations in attentional processing. However, it remains unclear whether individuals in high risk professions, who are skilled at making rapid decisions in emergency situations, show altered threat-induced freezing. Here we investigated the effect of incident...
article 2017
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Kong, G. (author), Alais, D. (author), van der Burg, E.D. (author)
article 2017
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Hermus, M.A.A. (author), Hitzert, M. (author), Boesveld, I.I. (author), van den Akker-van Marle, E.M. (author), van Dommelen, P. (author), Franx, A. (author), de Graaf, J.P. (author), van Lith, J.M.M. (author), Steegers, E.E. (author), Wiegers, T.A. (author), van der Pal-de Bruin, K.K. (author)
Objectives To compare the Optimality Index of planned birth in a birth centre with planned birth in a hospital and planned home birth for low-risk term pregnant women who start labour under the responsibility of a community midwife. Design Prospective cohort study. Setting Low-risk pregnant women under care of a community midwife and living in a...
article 2017
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Andersen, L.L. (author), Fishwick, D. (author), Robinson, E. (author), Wiezer, N.M. (author), Mockałło, Z. (author), Grosjean, V. (author)
Aim: Workers who are satisfied with their job are the cornerstones of healthy and productive companies. This study investigated factors associated with job satisfaction in the general working population. Methods: From the 2010 round of the Danish Work Environment Cohort Study, currently employed wage earners (N=10,427) replied to questions about...
article 2017
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van der Veen, M.H. (author), Volgenant, C.M.C. (author), Keijser, B. (author), ten Cate, J.M. (author), Crielaard, W. (author)
Objectives The dynamics of red fluorescent plaque (RFP) in comparison to clinical plaque and bleeding scores were studied during an experimental gingivitis protocol in a cohort of healthy participants. Methods Forty-one participants were monitored for RFP before (24 h plaque), during 14 days plaque accumulation (days 2, 5, 9, 14) and after 7...
article 2016
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van Loon, K. (author), Breteler, M.J.M. (author), van Wolfwinkel, L. (author), Rheineck Leyssius, A.T. (author), Kossen, A.S. (author), Kalkman, C.J. (author), van Zaane, B. (author), Peelen, L.M. (author)
Altered respiratory rate is one of the first symptoms of medical conditions that require timely intervention, e.g., sepsis or opioid-induced respiratory depression. To facilitate continuous respiratory rate monitoring on general hospital wards a contactless, non-invasive, prototype monitor was developed using frequency modulated continuous wave...
article 2016
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Kong, G. (author), Alais, D. (author), van der Burg, E.D. (author)
In the present study, we examine how observers search among complex displays. Participants were asked to search for a big red horizontal line among 119 distractor lines of various sizes, orientations and colours, leading to 36 different feature combinations. To understand how people search in such a heterogeneous display, we evolved the search...
article 2016
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Bernaards, C. (author), Hildebrandt, V.H. (author), Hendriksen, I.J. (author)
Background. Evidence shows that prolonged sitting is associated with an increased risk of mortality, independent of physical activity (PA). The aim of the study was to identify correlates of sedentary time (ST) in different age groups and day types (i.e. school-/work day versus non-school-/non-work day). Methods. The study sample consisted of...
article 2016
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Schrieks, I.C. (author), Heil, A.L. (author), Hendriks, H.F. (author), Mukamal, K.J. (author), Beulens, J.W. (author)
OBJECTIVE: Moderate alcohol consumption is associated with a reduced risk of type 2 diabetes. This reduced risk might be explained by improved insulin sensitivity or improved glycemic status, but results of intervention studies on this relation are inconsistent. The purpose of this study was to conduct a systematic review and meta-analysis of...
article 2015
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Vlaming, M.L. (author), van Duijn, E. (author), Dillingh, M.R. (author), Brands, R. (author), Windhorst, A.D. (author), Hendrikse, N.H. (author), Bosgra, S. (author), Burggraaf, J. (author), de Koning, M.C. (author), Fidder, A. (author), Mocking, J.A. (author), Sandman, H. (author), de Ligt, R.A. (author), Fabriek, B.O. (author), Pasman, W.J. (author), Seinen, W. (author), Alves, T. (author), Carrondo, M. (author), Peixoto, C. (author), Peeters, P.A. (author), Vaes, W.H. (author)
Preclinical development of new biological entities (NBEs), such as human protein therapeutics, requires considerable expenditure of time and costs. Poor prediction of pharmacokinetics in humans further reduces net efficiency. In this study, we show for the first time that pharmacokinetic data of NBEs in humans can be successfully obtained early...
article 2015
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