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Vos, M. (author), Roelse, V. (author), Koopmans, L. (author), van der Torre, W. (author), Xavier, M. (author), van der Horst, A. (author), van Nispen, I. (author), Sanders, J. (author)
De arbeidsmarkt verandert snel. Technologische ontwikkelingen zoals robotisering en digitalisering hebben grote impact op het werk. Taken en functies verdwijnen en er ontstaan nieuwe. Ook ingrijpende gebeurtenissen zoals de coronacrisis hebben grote impact op de inhoud van werk, bedrijfsprocessen en businessmodellen. Het is daarom belangrijk dat...
article 2021
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Westerneng, M. (author), de Jonge, A. (author), van Baar, A.L. (author), Witteveen, A.B. (author), Jellema, P. (author), Paarlberg, K.M. (author), Rijnders, M. (author), van der Horst, H.E. (author)
Background: Third-trimester routine ultrasounds are increasingly offered to monitor fetal growth. In addition to limited evidence for its clinical effectiveness, little is known about its importance for pregnancy-specific anxiety and mother-to-infant bonding. Methods: 1275 low-risk women participated in a Dutch nationwide pragmatic cluster...
article 2021
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van der Horst, A.R.A. (author), Thierry, M.C. (author), Vet, J.M. (author), Fazlur Rahman, A.K.M. (author)
With 21,000 people annually killed in road traffic (estimated figure by World Health Organization), Bangladesh has one of the highest fatality rates in the world. Vulnerable road users (VRUs) account for over 50% of road traffic casualties, and 70% of casualties occur in rural areas. As in many Low and Middle Income Countries (LMICs), the...
article 2017
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van der Horst, A.R.A. (author), Thierry, M.C. (author), Vet, J.M. (author), Rahman, A.F. (author)
With 21,000 people annually killed in road traffic (estimated figure by World Health Organization), Bangladesh has one of the highest fatality rates in the world. Vulnerable road users (VRUs) account for over 50% of road traffic casualties, and 70% of casualties occur in rural areas. As in many Low and Middle Income Countries (LMICs), the...
article 2016
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van der Horst, A.R.A. (author), de Goede, M. (author), de Hair-Buijssen, S.H.H.M. (author), Methorst, R. (author)
In The Netherlands, on bicycle paths, single-bicycle accidents, bicycle-bicycle and bicycle-moped accidents constitute a considerable share of all bicyclist injuries. Over three quarters of all hospitalised bicyclist victims in the Netherlands cannot be directly related to a crash with motorised traffic. As the usage of bicycle paths steadily...
article 2014
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van der Horst, T.J.J. (author)
Ondanks voorzichtige tekenen van herstel is de verwachting dat de Nederlandse economie de komende jaren slechts beperkt zal groeien. Dit roept de vraag op of Nederland toe is aan een nieuw groeimodel. In de nieuwste editie van de staat van Nederland Innovatieland verkennen TNO en HCSS de achtergronden van de huidige economische ontwikkeling en...
article 2014
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Bökkerink, M. (author), van der Horst, J. (author), Wijnmalen, J.D. (author)
In het artikel 'Hoe solide is de Nederlandse (en de Britse) 'Nationale Risicobeoordeling?'beoordeelt Charles Vlek de methode van de Nederlandse Nationale Risicobeoordeling (NRB). We verwelkomen kritische beschouwingen en suggesties die ons helpen methodische en praktische problemen te onderkennen en op te lossen. Wij waarderen daarom het artikel...
article 2013
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van Beijsterveldt, A.M.C. (author), van der Horst, N. (author), van de Port, I.G.L. (author), Backx, F.J.G. (author)
The incidence of soccer (football) injuries is among the highest in sports. Despite this high rate, insufficient evidence is available on the efficacy of preventive training programmes on injury incidence. Objective To systematically study the evidence on preventive exercise-based training programmes to reduce the incidence of injuries in soccer...
article 2013
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van Nes, N. (author), Christoph, M. (author), Hoedemaeker, M. (author), van der Horst, A.R.A. (author)
Naturalistic driving studies are increasingly applied in different shapes and sizes. The European project PROLOGUE has investigated the value and feasibility of a large-scale naturalistic driving study in Europe. Within PROLOGUE several pilot studies have been conducted in different countries. The Dutch field trial investigated the value and...
article 2013
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Boon, M.R. (author), van den Berg, S.A.A. (author), Wang, Y. (author), van den Bossche, J. (author), Karkampouna, S. (author), Bauwens, M. (author), de Saint-Hubert, M. (author), van der Horst, G. (author), Vukicevic, S. (author), de Winther, M.P.J. (author), Havekes, L.M. (author), Jukema, J.W. (author), Tamsma, J.T. (author), van der Pluijm, G. (author), van Dijk, K.W. (author), Rensen, P.C.N. (author)
Background/Aims:Brown adipose tissue (BAT) dissipates energy stored in triglycerides as heat via the uncoupling protein UCP-1 and is a promising target to combat hyperlipidemia and obesity. BAT is densely innervated by the sympathetic nervous system, which increases BAT differentiation and activity upon cold exposure. Recently, Bone...
article 2013
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van der Horst, A.R.A. (author), Hogema, J.H. (author)
With increasing traffic demands and various attempts to get maximum performance out of the road traffic system, the driving task is becoming more and more complex, and the more important it is to consider the human factor in highway design and operation. Successful introduction of new driver support systems, dynamic traffic management systems,...
article 2011
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van der Horst, E. (author), Peironcely, J.E. (author), van Westen, G.J.P. (author), van den Hoven, O.O. (author), Galloway, W.R.J.D. (author), Spring, D.R. (author), Wegner, J.K. (author), van Vlijmen, H.W.T. (author), Ijzerman, A.P. (author), Overington, J.P. (author), Bender, A. (author)
Chemogenomic approaches, which link ligand chemistry to bioactivity against targets (and, by extension, to phenotypes) are becoming more and more important due to the increasing number of bioactivity data available both in proprietary databases as well as in the public domain. In this article we review chemogenomics approaches applied in four...
article 2011
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Feenstra, P.J. (author), van der Horst, A.R.A. (author), Grácio, B.J.C. (author), Wentink, M. (author), TNO Defensie en Veiligheid (author)
The goal of the present study was to explore how simulator motion cuing affects the driver's control performance of a car. Steering behavior was used as a measure of control performance. The experimental task was a slalom maneuver in which the velocity of the car was limited to 70 km/h. Subjective and objective variables were measured. The paper...
article 2010
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van der Horst, A.R.A. (author), TNO Defensie en Veiligheid (author)
Naar aanleiding van het artikel ' Nieuw generatie bewegwijzering turborotondes en turbopleinen' formuleert de redactie de stelling: 'Implementatie van nieuwe verkeersontwerpen is pas verantwoord als na laboratoriumonderzoeken eerst praktijktoetsen zijn uitgevoerd'. Richard van der Horst, human factors onderzoeker bij TNO, geeft een reactie.
article 2010
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van der Horst, A.R.A. (author), Klunder, G. (author), TNO Defensie en Veiligheid (author)
article 2009
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TNO Defensie en Veiligheid (author), van der Horst, A.R.A. (author), Klunder, G. (author)
article 2009
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Schaap, T.W. (author), van der Horst, A.R.A. (author), van Arem, B. (author), Brookhuis, K.A. (author), TNO Defensie en Veiligheid (author)
At urban intersections drivers handle multiple tasks simultaneously, making urban driving a complex task. An advanced driver assistance system may support drivers in this specific driving task, but the design details of such a system need to be determined before they can be fully deployed. A driving simulator experiment was conducted to...
article 2008
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van Arem, B. (author), van der Horst, A.R.A. (author), TNO Defensie en Veiligheid (author)
De mobiliteit van personen en goederen is onmisbaar binnen ons dagelijks leven en maatschappij. In Nederland nemen 7 miljoen personenauto's ruim 80% van onze verplaatsingen voor hun rekening. Zo'n 60% van de goederen wordt over de weg vervoerd en 30% over het water. Berekeningen van het ministerie van Verkeer en Waterstaat voorspellen een...
article 2008
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van der Horst, R. (author), Martens, M. (author), TNO Defensie en Veiligheid (author)
In one way or another, human factors play a role in almost all road accidents. For designing a safe traffic and road environment, it is important to take human capabilities and limitations into account: man asthe measure of all things. This paper briefly summarizes traffic safetyfrom a road users' point ofview,givesa general description...
article 2008
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van Bezooijen, R.L. (author), Svensson, J.P. (author), Eefting, D. (author), Visser, A. (author), van der Horst, G. (author), Karperien, M. (author), Quax, P.H.A. (author), Vrieling, H. (author), Papapoulos, S.E. (author), ten Dijke, P. (author), Löwik, W.G.M.C. (author), TNO Kwaliteit van Leven (author)
Sclerostin is an osteocyte-derived negative regulator of bone formation. It inhibits BMP-stimulated bone formation both in vitro and in vivo but has no direct effect on BMP signaling. Instead, sclerostin inhibits Wnt signaling that is required for BMP-stimulated osteoblastic differentiation. Introduction: Sclerostin is a member of the Dan family...
article 2007
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