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Westerneng, M. (author), de Jonge, A. (author), van Baar, A.L. (author), Witteveen, A.B. (author), Jellema, P. (author), Paarlberg, K.M. (author), Rijnders, M. (author), van der Horst, H.E. (author)
Background: Third-trimester routine ultrasounds are increasingly offered to monitor fetal growth. In addition to limited evidence for its clinical effectiveness, little is known about its importance for pregnancy-specific anxiety and mother-to-infant bonding. Methods: 1275 low-risk women participated in a Dutch nationwide pragmatic cluster...
article 2022
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Rahman, S. (author), Davids, M. (author), van Hamersveld, P.H.P. (author), Welting, O. (author), Rahaoui, H. (author), Schuren, F. (author), Meijer, S.L. (author), van den Wijngaard, R.M. (author), Hakvoort, T.B.M. (author), de Jonge, W.J. (author), Heinsbroek, S.E.M. (author)
β-glucan consumption is known for its beneficial health effects, but the mode of action is unclear. While humans and mice lack the required enzymes to digest β-glucans, certain intestinal microbes can digest β-glucans, triggering gut microbial changes. Curdlan, a particulate β-glucan isolated from Alcaligenes faecalis, is used as a food additive...
article 2021
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Stroek, K. (author), Heijboer, A.C. (author), van Veen-Sijne, M. (author), Bosch, A.M. (author), Ploeg C.P.B. van der, (author), Zwaveling-Soonawala, N. (author), de Jonge, R. (author), van Trotsenburg, A.S.P. (author), Boelen, A. (author)
Introduction: Newborn screening (NBS) for congenital hypothyroidism (CH) in the Netherlands consists of thyroxine (T4), thyroid-stimulating hormone (TSH), and T4-binding globulin (TBG) measurements to detect thyroidal CH and central CH (CH-C). CH-C is detected by T4 or a calculated T4/TBG ratio, which serves as an indirect measure of free T4....
article 2021
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Rahman, S. (author), Ghiboud, M. (author), Donkers, J.M. (author), van de Steeg, E. (author), van Tol, E.A.F. (author), Hakvoort, T.B.M. (author), de Jonge, W.J. (author)
Over the past years, several preclinical in vitro and ex vivo models have been developed that helped to understand some of the critical aspects of intestinal functions in health and disease such as inflammatory bowel disease (IBD). However, the translation to the human in vivo situation remains problematic. The main reason for this is that these...
article 2021
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Stroek, K. (author), Heijboer, A.C. (author), Bouva, M.J. (author), van der Ploeg, C.P.B. (author), Heijnen, M.L.A. (author), Weijman, G. (author), Bosch, A.M. (author), de Jonge, R. (author), Schielen, P.C.J.I. (author), van Trotsenburg, A.S.P. (author), Boelen, A. (author)
Objective: Congenital hypothyroidism (CH) is defined as thyroid hormone deficiency at birth due to disorders of the thyroid gland (thyroidal CH, CH-T), or the hypothalamus or pituitary (central CH, CH-C). The Dutch Newborn Screening (NBS) strategy is primarily based on determination of thyroxine (T4) concentrations in dried blood spots followed,...
article 2020
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Botschuijver, S. (author), van Diest, S.A. (author), van Thiel, I.A.M. (author), Saia, R.S. (author), Strik, A.S. (author), Yu, Z. (author), Maria-Ferreira, D. (author), Welting, O. (author), Keszthelyi, D. (author), Jennings, G. (author), Heinsbroek, S.E.M. (author), Elferink, R.P.O. (author), Schuren, F.H.J. (author), de Jonge, W.J. (author), van den Wijngaard, R.M. (author)
Irritable bowel syndrome (IBS) is a heterogenic, functional gastrointestinal disorder of the gut-brain axis characterized by altered bowel habit and abdominal pain. Preclinical and clinical results suggested that, in part of these patients, pain may result from fungal induced release of mast cell derived histamine, subsequent activation of...
article 2019
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Botschuijver, S. (author), Welting, O. (author), Levin, E. (author), Maria-Ferreira, D. (author), Koch, E. (author), Montijn, R.C. (author), Seppen, J. (author), Hakvoort, T.B.M. (author), Schuren, F.H.J. (author), de Jonge, W.J. (author), van den Wijngaard, R.M. (author)
Background: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder associated with altered gastrointestinal microflora and increased nociception to colonic distension. This visceral hypersensitivity can be reversed in our rat maternal separation model by fungicides. Menthacarin® is a proprietary combination of essential oils from...
article 2018
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Niks, I.M.W. (author), Gevers, J.M.P. (author), de Jonge, J. (author), Houtman, I.L.D. (author)
Effective interventions to prevent work stress and to improve health, well-being, and performance of employees are of the utmost importance. This quasi-experimental intervention study presents a specific method for diagnosis of psychosocial risk factors at work and subsequent development and implementation of tailored work stress interventions,...
article 2018
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Botschuijver, S. (author), Roeselers, G. (author), Levin, E. (author), Jonkers, D.M. (author), Welting, O. (author), Heinsbroek, S.E.M. (author), de Weerd, H.H. (author), Boekhout, T. (author), Fornai, M. (author), Masclee, A.A. (author), Schuren, F.H.J. (author), de Jonge, W.J. (author), Seppen, J. (author), van den Wijngaard, R.M. (author)
Background & Aims Visceral hypersensitivity is one feature of irritable bowel syndrome (IBS). Bacterial dysbiosis might be involved in the activation of nociceptive sensory pathways, but there have been few studies of the role of the mycobiome (the fungal microbiome) in the development of IBS. We analyzed intestinal mycobiomes of patients with...
article 2017
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Perdok, H. (author), Cronie, D. (author), van der Speld, C. (author), van Dillen, J. (author), de Jonge, A. (author), Rijnders, M. (author), de Graaf, I. (author), Schellevis, F.G. (author), Verhoeven, G. (author)
Objective High levels of experienced job autonomy are found to be beneficial for healthcare professionals and for the relationship with their patients. The aim of this study was to assess how maternity care professionals in the Netherlands perceive their job autonomy in the Dutch maternity care system and whether they expect a new system of...
article 2017
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Keuken, M.P. (author), Moerman, M. (author), Voogt, M. (author), Zandveld, P. (author), Verhagen, H. (author), Stelwagen, U. (author), de Jonge, D. (author)
In this study, NOx and particle number concentration (PNC) at an urban background and a traffic location were measured in the city of Amsterdam (the Netherlands). Modelled and measured contributions to NOx and PNC at the traffic location were used to derive real-world PN emission factors for average urban road traffic. The results for NOx were...
article 2016
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Niks, I.M.W. (author), Gevers, J.M.P. (author), de Jonge, J. (author), Houtman, I.L.D. (author)
It is well-known that recovery from work and job resources can counteract negative effects of high job demands, but less is known about how off-job recovery and job resources are related to each other. In this two-level daily diary study, 67 employees filled out daily surveys over the course of 8 days to examine this issue. Consistent with our...
article 2016
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Perdok, H. (author), Jans, S. (author), Verhoeven, C. (author), Henneman, L. (author), Wiegers, T. (author), Mol, B.W. (author), Schellevis, F. (author), de Jonge, A. (author)
Background This study aims to give insight into the opinions of maternity care professionals and other stakeholders on the integration of midwife-led care and obstetrician-led care and on the facilitating and inhibiting factors for integrating maternity care. Methods Qualitative study using interviews and focus groups from November 2012 to...
article 2016
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Offerhaus, P.M. (author), de Jonge, A. (author), van der Pal-de Bruin, K.M. (author), Hukkelhoven, C.W.P.M. (author), Scheepers, P.L.H. (author), Lagro-Janssen, A.L.M. (author)
Objective: to study whether an increase in intrapartum referrals in primary midwife-led care births in the Netherlands is accompanied by an increase in caesarean sections. Design: nationwide descriptive study. Setting: The Netherlands Perinatal Registry. Participants: 807,437 births of nine year cohorts of women with low risk pregnancies in...
article 2015
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Offerhaus, P.M. (author), Otten, W. (author), Boxem-Tiemessen, J.C. (author), de Jonge, A. (author), van der Pal-de Bruin, K.M. (author), Scheepers, P.L. (author), Lagro-Janssen, A.L. (author)
Objective in midwife-led care models of maternity care, midwives are responsible for intrapartum referrals to the obstetrician or obstetric unit, in order to give their clients access to secondary obstetric care. This study explores the influence of risk perception, policy on routine labour management, and other midwife related factors on...
article 2015
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Offerhaus, P.M. (author), de Jonge, A. (author), van der Pal-de Bruin, K.M. (author), Hukkelhoven, C.W.P.M. (author), Scheepers, P.L.H. (author), Lagro-Janssen, A.L.M. (author)
article 2015
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Offerhaus, P.M. (author), de Jonge, A. (author), van der Pal-de Bruin, K.M. (author), Hukkelhoven, C.W.P.M. (author), Scheepers, P.L.H. (author), Lgero-Jansen, A.L.M. (author)
OBJECTIVE: to study whether an increase in intrapartum referrals in primary midwife-led care births in the Netherlands is accompanied by an increase in caesarean sections. DESIGN: nationwide descriptive study. SETTING: the Netherlands Perinatal Registry. PARTICIPANTS: 789,795 births of nine year cohorts of women with low risk pregnancies in...
article 2014
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Kher, S.V. (author), de Jonge, J. (author), Wentholt, M.T. (author), Deliza, R. (author), de Andrade, J.C. (author), Cnossen, H.J. (author), Lucas Luijckx, N.B. (author), Frewer, L.J. (author)
The development and implementation of effective systems to identify vulnerabilities in food chains to chemical and microbiological contaminants must take account of consumer priorities and preferences. The present investigation attempted to understand consumer perceptions associated with chemical and microbiological contaminants in four specific...
article 2013
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Offerhaus, P.M. (author), Hukkelhoven, C.W.P.M. (author), de Jonge, A. (author), van der Pal-de Bruin, K.M. (author), Scheepers, P.L.H. (author), Lagro-Janssen, A.L.M. (author)
Background: There are concerns about the Dutch maternity care system, characterized by a strict role division between primary and secondary care. The objective of this study was to describe trends in referrals and in perinatal outcomes among labors that started in primary midwife-led care. Methods: We performed a descriptive study of all 789,795...
article 2013
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Niks, I.M.W. (author), de Jonge, J. (author), Gevers, J.M.P (author), Houtman, I.L.D. (author)
Background: It is well-known that health care workers in today's general hospitals have to deal with high levels of job demands, which could have negative effects on their health, well-being, and job performance. A way to reduce job-related stress reactions and to optimize positive work-related outcomes is to raise the level of specific job...
article 2013
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