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Volkers, R.J.M. (author), de Jong, A.L. (author), Hulst, A.G. (author), van Baar, B.L.M. (author), de Bont, J.A.M. (author), Wery, J. (author), TNO Kwaliteit van Leven TNO Defensie en Veiligheid (author)
The aim of this study was to assess the cellular response of the solvent-tolerant Pseudomonas putida S12 to toluene as the single effector. Proteomic analysis (two-dimensional difference-in-gel-electrophoresis) was used to assess the response of P. putida S12 cultured in chemostats. This approach ensures constant growth conditions, both in the...
article 2006
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Noort, D. (author), Hulst, A.G. (author), Fidder, A. (author), van Gurp, R.A. (author), de Jong, L.P.A. (author), Benschop, H.P. (author), Prins Maurits Laboratorium TNO (author)
The development of procedures for retrospective detection and quantitation of exposure to phosgene, based on adducts to hemoglobin and albumin, is described. Upon incubation of human blood with [14C]phosgene (0-750 μM), a significant part of radioactivity (0-13%) became associated with globin and albumin. Upon Pronase digestion of globin, one of...
article 2000
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van Put, M.A. (author), de Jong, J.D. (author)
Bij houten weg- en water bouwconstructies blijft er vaak water staan tussen aansluitingen van constructiedelen. Het vochtgehalte van het hout stijgt, met versnelde materiaaldegradatie tot gevolg. De ontwateringsplaat, een innovatie van TNO, gaat houtrot op verbindingspunten tegen
article 2015
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de Jong, G. (author), TNO Bouw (author)
This research note addresses the governance structure of innovation processes in high-tech alliances, focusing on the content and role of formal contracts. Contract research is strongly heterogeneous, that is, many different paradigms, concepts, definitions and measures exist. We discuss the most important aspects of contract research and...
article 2008
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Pierik, F.H. (author), Burdorf, A. (author), de Jong, F.H. (author), Weber, R.F.A. (author), TNO Bouw (author)
Subfertilíty affects about 1 59b of all couples. Assessment of spermatogenesis has a central role in the evaluation of the subfertile couple. Classical markers of spermatogenesis, such as semen analysis, testicular biopsy and endocrine evaluation all have their diagnostic limitations. There is a clear need for accurate additional markers of...
article 2003
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de Jong, A.R. (author), Boumans, H. (author), Slaghek, T. (author), van Veen, J. (author), Rijk, R. (author), van Zandvoort, M.M.J. (author), TNO Kwaliteit van Leven (author)
This paper gives an overview of the legal consequences of a new EU framework regulation on food contact materials which includes controls on active and intelligent packaging. Recent developments in active and intelligent packaging systems are described, two examples of which aim at achieving improvements in quality and safety of food products....
article 2005
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Sutanudjaja, E.H. (author), van Beek, L.P.H. (author), de Jong, S.M. (author), van Geer, F.C. (author), Bierkens, M.F.P. (author)
The current generation of large-scale hydrological models does not include a groundwater flow component. Large-scale groundwater models, involving aquifers and basins of multiple countries, are still rare mainly due to a lack of hydro-geological data which are usually only available in developed countries. In this study, we propose a novel...
article 2011
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Nieuwenhuizen, W.F. (author), Dekker, H.L. (author), de Koning, L.J. (author), Gröneveld, T. (author), de Koster, C.G. (author), de Jong, G.A.H. (author)
The molecular structures determine the physical properties of milk proteins and are important for the texture of many dairy-based foods. Bovine α-lactalbumin (α-LA) is a globular 123 amino acid Ca2+ binding milk protein. Modification with microbial Ca2+ independent transglutaminase (MTGase) was used to modify lysines and glutamines in holo and...
article 2003
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de Jong, A.M. (author), Vink, P. (author), TNO Arbeid (author)
This paper evaluates a step-by-step participatory approach to better work, applied in reducing the musculoskeletal workload in installation work. To arrive at a reduction in workload, a steering group led the project through the following steps: Introduction: defining the goal and informing all 7000 employees. Analysis: finding major loading...
article 2002
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Verhagen, T. (author), Woering, A. (author), Ubink, E. (author), Knijnenburg, S. (author), de Jong, K. (author), van Helden, H. (author), TNO Defensie en Veiligheid (author)
article 2008
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Draaijers, G.P.J. (author), van Leeuwen, E.P. (author), de Jong, P.G.H. (author), Erisman, J.W. (author), TNO Milieu, Energie en Procesinnovatie (author)
Deposition of base cations (Na+, Mg2+, Ca2+, K+) in Europe was mapped for 1989 with a spatial resolution of 10 x 20 km using the so-called inferential modeling technique. Deposition fields resembled the geographic variability of sources, land-use and climate. Dry deposition constituted on average 45% of the total base cation deposition in Europe...
article 1997
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Jansen, H.W. (author), de Jong, C.A.F. (author)
Thecontributionofshippingnoisetothebackground noise in the seas can be estimated by shipping noise maps. Noise maps can be made by applying appropriate modeling tools for underwater sound propagation and ship source levels to information on the acoustic environment and on the ship traffic in the area of the map. The development of reliable source...
article 2017
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de Jong, L. (author), Bobeldijk-Pastorova, I. (author), Erdmann, J. (author), Bijker-Schreurs, M. (author), Schunkert, H. (author), Kuivenhoven, J.A. (author), van Gool, A.J. (author)
Research consortia in Europe often compete with each other for skills, human and technical resources and, eventually, recognition of the scientific impact of their work. In response to the same EU Horizon2020 call, we received funding for our research project proposals to identify and validate novel drug targets for cardiovascular disease...
article 2020
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de Jongh, H.H.J. (author), de Jong, G.A.H. (author), Apostolovic, D. (author), Taylor, S.L. (author), Baumert, J.L. (author), Koppelman, S.J. (author)
This work reports on the effect of heat treatment on the protein conformational stability of intact and post-translationally cleaved peanut allergen Ara h 6 in relation to IgE-binding. Intact and post-translationally cleaved Ara h 6 are structurally similar and their strong resistance to denaturant-induced unfolding is comparable. Only upon...
article 2020
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de Jong, J. (author), TNO Bouw en Ondergrond (author)
article 2008
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van Neer, P.L.M.J. (author), Danilouchkine, M.G. (author), Matte, G.M. (author), van der Steen, A.F.W. (author), de Jong, N. (author)
Tissue second-harmonic imaging is currently the default mode in commercial diagnostic ultrasound systems. A new modality, superharmonic imaging (SHI), combines the third through fifth harmonics originating from nonlinear wave propagation through tissue. SHI could further improve the resolution and quality of echographic images. The...
article 2011
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de Keizer, C. (author), de Jong, M.M. (author), Mendes, T. (author), Katiyar, M. (author), Folkerts, W. (author), Rindt, C. (author), Zondag, H.A. (author)
Recently, there has been a lot of interest in PV thermal systems, which generate both heat and power. Within the WenSDak project, several companies and research institutes work together to (further) develop several uncovered PVT collectors. The outdoor performance of prototypes of these collectors is being evaluated in an outdoor test setup. The...
article 2015
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Waardenburg, M. (author), Groenleer, M. (author), de Jong, J. (author), Keijser, B.M.J. (author)
The literature suggests that collaborative governance efforts typically face three types of challenges: substantive problem-solving challenges, collaborative process challenges and multi-relational accountability challenges. In this article, we investigate how these challenges manifest themselves in practice and explore potential ways in which...
article 2020
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Pierik, F.H. (author), Deddens, J.A. (author), Burdorf, A. (author), de Muinck Keizer-Schrama, S.M.P.F. (author), de Jong, F.H. (author), Weber, R.F.A. (author), TNO Bouw (author)
article 2008
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de Jong, T. (author), Wiezer, N. (author), de Weerd, M. (author), Nielsen, K. (author), Mattila-Holappa, P. (author), Mockałłod, Z. (author)
This is a review of published longitudinal empirical research on the impact of restructuring on employee well-being. We investigated whether restructuring accompanied by staff reductions impacts differently on worker well-being than restructuring without staff reductions, and the differences between short- and long-term effects of restructuring....
article 2016
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