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Tromp, P.C. (author), Sspaan, S. (author), ten Brug, B.M. (author)
report 2022
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Franken, R. (author), Tromp, P. (author), van de Hoef, W. (author), Jadoenathmisier, T. (author)
article 2021
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Small, J. (author), van Hoek, C. (author), van der Does, F. (author), Seinen, A.B. (author), Melzer, S. (author), Tromp, P.C. (author), van der Laan, S. (author)
A method has been developed to screen large numbers (~103–104 per sample) of coarse airborne dust particles for the occurrence of Pb-rich phases, together with quantification of the particles’ mineralogy, chemistry, and inferred provenance. Using SEM-EDS spectral imaging (SI) at 15 kV, and processing with the custom software PARC, screening of...
article 2021
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Tromp, P.C. (author), van Dinther, D. (author), de Bie, S.E. (author), Duyzer, J. (author), Lollinga, J.P. (author), Moerman, M.M. (author), Henke, S.J. (author)
De laatste jaren is er toenemende aandacht voor zeer kleine deeltjes stof in lucht. Dit ultrafijn stof (UFP) bestaat uit deeltjes met een diameter kleiner dan 100 nm. Deze deeltjesfractie zou nadelige effecten kunnen hebben op de gezondheid (Janssen et al, 2016; Lammers et al., 2020). Recentelijk uitgevoerde metingen van TNO, in samenwerking met...
report 2021
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Blanco-Martinez, J. (author), Guo, X. (author), van Leeuwen, S. (author), Snets, J. (author), Tromp, S. (author), Woltering, E. (author), Bhoraskar, A. (author), Zomer, G.R. (author), Hoenderken, P. (author)
Food supply is one of the main challenges our global society faces, and supply chain innovation is expected to contribute to a secure, efficient and sustainable food supply. The Netherlands plays a significant role in the global food supply system. In supply chains of fresh and perishable food products even minor disruptions in storage/transport...
report 2021
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Memelink, R.G. (author), Pasman, W.J. (author), Bongers, A. (author), Tump, A. (author), van Ginkel, A. (author), Tromp, W. (author), Wopereis, S. (author), Verlaan, S. (author), den Bosch, J.V.V. (author), Weijs, P.J.M. (author)
Background: Weight loss is key to treatment of older adults with obesity and type 2 diabetes, but also a risk for muscle mass loss. This study investigated whether a whey protein drink enriched with leucine and vitamin D could preserve muscle mass and improve glycemic control during combined lifestyle intervention in this population. Methods:...
article 2021
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Spaan, S. (author), Tromp, P. (author), Lucas Luijckx, N. (author), de Weerd, H. (author), ten Brug, B. (author), Franken, R. (author), Schinkel, J. (author)
report 2021
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Spaan, S. (author), Tromp, P. (author), Lucas Luijckx, N.B. (author)
report 2021
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Peters, R.J.B. (author), Oomen, A.G. (author), van Bemmel, G. (author), van Vliet, L. (author), Undas, A.K. (author), Munniks, S. (author), Bleys, R.L.A.W. (author), Tromp, P.C. (author), Brand, W. (author), van der Lee, M. (author)
Silicon dioxide (silica, SiO2, SAS) and titanium dioxide (TiO2) are produced in high volumes and applied in many consumer and food products. As a consequence, there is a potential human exposure and subsequent systemic uptake of these particles. In this study we show the characterization and quantification of both total silicon (Si) and titanium...
article 2020
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Ndika, J. (author), Ilves, M. (author), Kooter, I.M. (author), Grollers-Mulderij, M. (author), Duistermaat, E. (author), Tromp, P.C. (author), Kuper, F. (author), Kinaret, P. (author), Greco, D. (author), Karisola, P. (author), Alenius, H. (author)
The diversity and increasing prevalence of products derived from engineered nanomaterials (ENM), warrants implementation of non-animal approaches to health hazard assessment for ethical and practical reasons. Although non-animal approaches are becoming increasingly popular, there are almost no studies of side-by-side comparisons with traditional...
article 2020
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Tromp, P.C. (author), Beeltje, H. (author), Okeme, J.O. (author), Vermeulen, R. (author), Pronk, A. (author), Diamond, M.L. (author)
Passive air sampling is increasingly used for air quality monitoring and for personal sampling. In a novel experimental exposure chamber study, 3 types of polydimethylsiloxane (PDMS, including sheet and wristband) and 1 type of polyurethane foam (PUF) passive air samplers were tested for gas-phase uptake of 200 semi volatile organic compounds ...
article 2019
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Kooter, I.M. (author), Ilves, M. (author), Grollers-Mulderij, M. (author), Duistermaat, E. (author), Tromp, P.C. (author), Kuper, F. (author), Kinaret, P. (author), Savolainen, K. (author), Greco, D. (author), Karisola, P. (author), Ndika, J. (author), Alenius, H. (author)
More than 5% of any population suffers from asthma, and there are indications that these individuals are more sensitive to nanoparticle aerosols than the healthy population. We used an air–liquid interface model of inhalation exposure to investigate global transcriptomic responses in reconstituted three-dimensional airway epithelia of healthy...
article 2019
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Spaan, S. (author), Jadoenathmisier, T. (author), Tromp, P. (author), van den Berg, C. (author), Schinke, J. (author)
report 2019
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Spaan, S. (author), Tromp, P.C. (author), Schinkel, J.M. (author)
report 2019
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Tromp, P. (author), Spaan, S. (author)
Sinds 1978 is asbestbeleid ontwikkeld en uitgevoerd, dat is gericht op het terugdringen van asbest in enigerlei vorm in het binnen- en buitenmilieu. Dit beleid heeft onder andere geleid tot een aanzienlijke reductie van de asbestvezelconcentratie in de buitenlucht.
report 2018
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Dankers, A.C.A. (author), Kuper, C.F. (author), Boumeester, A.J. (author), Fabriek, B.O. (author), Kooter, I.M. (author), Gröllers-Mulderij, M. (author), Tromp, P. (author), Nelissen, I. (author), Zondervan-Van Den Beuken, E.K. (author), Vandebriel, R.J. (author)
Exposure of humans to metal oxide nanoparticles (NPs) occurs mainly via air, and inhaled metal oxide NPs may generate inflammation. The aim of this study was to investigate the proinflammatory potential of six metal oxide NPs (CeO2, Mn2O3, CuO, ZnO, Co3O4 and WO3; 27–108 μg ml−1) using human primary 3-dimensional airway epithelium (MucilAir™)...
article 2018
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Spaan, S. (author), Tromp, P.C. (author), de Jong, R. (author), Diks, M.V. (author), Voogd, E. (author), Verhagen, H.I.M. (author), Moerman, M.M. (author), Schinkel, J.M. (author)
report 2018
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Heringa, M.B. (author), Peters, R.J.B. (author), Bleys, R.L.A.W. (author), van der Lee, M.K. (author), Tromp, P.C. (author), van Kesteren, P.C.E. (author), van Eijkeren, J.C.H. (author), Undas, A.K. (author), Oomen, A.G. (author), Bouwmeester, H. (author)
Background: Titanium dioxide (TiO2) is produced at high volumes and applied in many consumer and food products. Recent toxicokinetic modelling indicated the potential of TiO2 to accumulate in human liver and spleen upon daily oral exposure, which is not routinely investigated in chronic animal studies. A health risk from nanosized TiO2 particle...
article 2018
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Markus, A.A. (author), Krystek, P. (author), Tromp, P.C. (author), Parsons, J.R. (author), Roex, E.W.M. (author), de Voogt, P. (author), Laane, R.W.P.M. (author)
We investigated the occurrence of metal-based nanoparticles in a natural system, the river Dommel in the Netherlands. The river itself is well-studied as far as hydrology and water quality is concerned, easily accessible and contains one major wastewater treatment plant discharging onto this river. We sampled water from various locations along...
article 2018
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Downward, G.S. (author), Hu, W. (author), Rothman, N. (author), Reiss, B. (author), Tromp, P. (author), Wu, G. (author), Wei, F. (author), Xu, J. (author), Seow, W.J. (author), Chapman, R.S. (author), Lan, Q. (author), Vermeulen, R. (author)
Exposure to crystalline silica (quartz) has been implicated as a potential cause of the high lung cancer rates in the neighbouring counties of Xuanwei and Fuyuan, China, where the domestic combustion of locally sourced “smoky” coal (a bituminous coal) is responsible for some of the highest lung cancer rates in the nation, irrespective of gender...
article 2017
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