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Beulens, J.W.J. (author), de Zoete, E.C. (author), Kok, F.J. (author), Schaafsma, G. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)
Objective: Moderate alcohol consumption is associated with a decreased risk of type II diabetes. This study investigates the effect of moderate alcohol consumption on adipokines and insulin sensitivity. Subjects: Twenty healthy, lean (body mass index (BMI) 18.5-25 kg/m2; n=11) or overweight (BMI>27 kg/m2; n=9) men (18-25 years). Methods: Three...
article 2008
document
Beulens, J.W.J. (author), van den Berg, R. (author), Kok, F.J. (author), Helander, A. (author), Vermunt, S.H.F. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)
Background and aims: To investigate the effect of moderate alcohol consumption on lipoprotein-associated phospholipase A2 activity, markers of inflammation and oxidative stress and whether these effects are modified by BMI. Methods and results: Eleven lean (BMI: 18.5-25 kg/m2) and 9 overweight (BMI > 27 kg/m2) men participated in a randomized...
article 2008
document
Hille, E.T.M. (author), Weisglas-Kuperus, N. (author), van Goudoever, J.B. (author), Jacobusse, G.W. (author), Ens-Dokkum, M.H. (author), de Groot, L. (author), Wit, J.M. (author), Geven, W.B. (author), Kok, J.H. (author), de Kleine, M.J.K. (author), Kollée, L.A.A. (author), Mulder, A.L.M. (author), van Straaten, H.L.M. (author), de Vries, L.S. (author), van Weissenbruch, M.M. (author), Verloove-Vanhorick, S.P. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE. Young adults who were born very preterm or with a very low birth weight remain at risk for physical and neurodevelopmental problems and lower academic achievement scores. Data, however, are scarce, hospital based, mostly done in small populations, and need additional confirmation. METHODS. Infants who were born at <32 weeks of...
article 2007
document
Hille, E.T.M. (author), van Straaten, H.L.M. (author), Verkerk, P.H. (author), van Straaten, I. (author), Verkerk, P. (author), Hille, E. (author), Baerts, W. (author), Bunkers, C. (author), Smink, E. (author), van Elburg, R. (author), de Kleine, M. (author), Kok, J.H. (author), Ilsen, A. (author), Visser, D. (author), Steiner, K. (author), de Vries, L.S. (author), Weisglas-Kuperus, N. (author), Sprij, A. (author), Lopriori, E. (author), Brokx, J. (author), Gavilanes, D. (author), Geven, W. (author), Bos, A. (author), TNO Kwaliteit van Leven (author)
Aim: To determine the prevalence and independent relationship between hearing loss and risk factors in a representative neonatal intensive care unit (NICU) population. Methods: Automated auditory brainstem response (AABR) hearing screening has been introduced since 1998 in the Dutch NICUs. After a second AABR failure, diagnostic ABR was used to...
article 2007
document
Verheijden, M.W. (author), Kok, F.J. (author), TNO Kwaliteit van Leven (author)
Community-based interventions have increasingly received attention since researchers and public health professionals have come to acknowledge the importance of an environment that makes the healthy choice the easy choice. All stakeholders including the target community are involved to achieve changes in legislation, in people's social and...
article 2005
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Beulens, J.W.J. (author), Sierksma, A. (author), Schaafsma, G. (author), Kok, F.J. (author), Struys, E.A. (author), Jakobs, C. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)
Background: Moderate alcohol consumption is associated with a decreased risk of cardiovascular disease. Because plasma homocysteine (tHcy) is considered an independent risk factor for cardiovascular disease and associated with alcohol consumption, the authors investigated the effect of moderate alcohol consumption on kinetics of plasma tHcy...
article 2005
document
Blom, W.A.M. (author), Stafleu, A. (author), de Graaf, C. (author), Kok, F.J. (author), Schaafsma, G. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)
Background: Ghrelin plays an important role in the regulation of food intake. Little is known about how ghrelin concentrations are modified by dietary factors. Objective: We examined the effects of both amount and type of carbohydrate on ghrelin concentrations and all correlations among the variables ghrelin, glucose, insulin, leptin, and all 4...
article 2005
document
van Straaten, H.L.M. (author), Hille, E.T.M. (author), Kok, J.H. (author), Verkerk, P.H. (author), Baerts, W. (author), Bunkers, C.M. (author), Smink, E.W.A. (author), van Elburg, R.M. (author), de Kleine, M.J.K. (author), Ilsen, A. (author), Maingay-Visser, A.P.G.F. (author), de Vries, L.S. (author), Weisglas-Kuperus, N. (author)
Aim: As part of a future national neonatal hearing screening programme in the Netherlands, automated auditory brainstem response (AABR) hearing screening was implemented in seven neonatal intensive care units (NICUs). The objective was to evaluate key outcomes of this programme: participation rate, first stage success rate, pass/referral rates,...
article 2003
document
Gómez-Aracena, J. (author), Martin-Moreno, J.M. (author), Riemersma, R.A. (author), Bode, P. (author), Gutiérrez-Bedmar, M. (author), Gorgojo, L. (author), Kark, J.D. (author), Garcia-Rodríguez, A. (author), Gomez-Gracia, E. (author), Kardinaal, A.F.M. (author), Aro, A. (author), van 't Veer, P. (author), Wedel, H. (author), Kok, F.J. (author), Fernández-Crehuet, J. (author)
The association between scandium status and risk of acute myocardial infarction (MI) was examined in a multicentre case control study in 10 centres from Europe and Israel. Scandium in toenails was assessed in 684 cases and 724 controls less than 70 years of age. Mean concentrations of toenail scandium were 6.74 μg/kg in cases and 7.75 μg/kg in...
article 2002
document
den Ouden, A.L. (author), Kok, J.H. (author), Verkerk, P.H. (author), Brand, R. (author), Verloove-Vanhorick, S.P. (author), TNO Preventie en Gezondheid (author)
Transient neonatal hypothyroxinemia is very common in preterm infants. The literature on the effect of this hypothyroxinemia is, however, controversial, and large or long-term follow-up studies are not available. In a nationwide prospective follow-up study on very preterm and (or) very low birth weight infants (n = 717), we studied the...
article 1996
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