Searched for: +
(1 - 20 of 28)

Pages

document
Brouwer, A. (author), Seifert, W.F. (author), Bosma, A. (author), van Leeuwen, R.E.W. (author), Hendriks, H.F.J. (author), Knook, D.L. (author), Gezondheidsorganisatie TNO Instituut voor verouderings- en vaatziekten onderzoek TNO Instituut voor toxicologie en voeding TNO (author)
conference paper 1992
document
Bergsma, J.H. (author), van Boxtel, J.A.M. (author), Kleijn de Vrankrijker, M.W. (author), Knook, D.L. (author), TNO Preventie en Gezondheid (author)
Abstract
conference paper 1995
document
Gezondheidsorganisatie TNO Instituut voor Experimentele Gerontologie TNO (author), Courtois, Y. (author), Faucheux, B. (author), Forette, B. (author), Knook, D.L. (author), Tréton, J.A. (author)
conference paper 1986
document
Knook, D.L. (author), Instituut voor verouderings- en vaatziekten onderzoek TNO (author)
bookPart 1993
document
Bezooijen, C.F.A. (author), de Gier, J.J. (author), Goedhard, W.J.A. (author), Gribnau, F.W.J. (author), Jonkers, J.R. (author), Knook, D.L. (author), van der Korst, J.K. (author), Offerhaus, L. (author), Schouten, J. (author), van Zwieten, P.A. (author), Instituut voor experimentele gerontologie TNO (author)
book 1980
document
Knook, D.L. (author), Goedhard, W.J.A. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
book 1985
document
Knook, D.L. (author), Goedhard, W.J.A. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
Gebaseerd op het 15e Gerontologie symposium 18 maart 1994 te Utrecht.
book 1994
document
Knook, D. (author), Ulrich, H. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
book 2003
document
Instituut voor experimentele gerontologie TNO (author), Eulderink, F. (author), Heeren, T.J. (author), Knook, D.L. (author), Ligthart, G.J. (author)
Dit boek bevat wat de basisarts moet weten over veroudering. Het behandelt eerst de belangrijkste aspecten van normale veroudering (Gerontologie), daarna de geneeskunde bij ouderen (Geriatrie) voor zover die anders is dan bij jongeren. Veroudering is het optreden van ogenschijnlijk spontane, irreversibele veranderingen met de tijd. Deze...
book 1993
document
Bosma, A. (author), Seifert, W.F. (author), Wilson, J.H.P. (author), Roholl, P.J.M. (author), Brouwer, A. (author), Knook, D.L. (author), Instituut voor Verouderings- en Vaatziekten Onderzoek TNO (author)
Rats of two strains (BN/BiRij and WAG/Rij) were fed the ethanol-containing Lieber-De Carli liquid diet supplemented with high amounts of vitamin A for 16 months. In contrast to Lieber and co-workers, who showed liver fibrosis developing within 9 months on the same diet in Sprague-Dawley rats, we were unable to demonstrate a histological and...
article 1991
document
Knook, D.L. (author), Instituut voor experimentele gerontologie TNO (author)
Ageing is associated with declines in the functional capacities of several organs. General causes for the decline can be divided into: 1. intrinsic cellular causes and 2. extracellular causes, e.g., changes in blood circulation and distribution. For the first group of causes, there is evidence for a decrease in the numbers of long-lived cells in...
article 1978
document
Heijmans, B.T. (author), Westendorp, R.G.J. (author), Knook, D.L. (author), Kluft, C. (author), Slagboom, P.E. (author), Gaubius Instituut TNO (author)
The factor V Leiden mutation (conferring resistance to activated protein C) has been implicated in the risk of arterial thrombosis and is a well-established risk factor for venous thrombosis especially in the elderly. We studied whether the disease association of the factor V mutation is reflected in an increased all-cause and cause-specific...
article 1998
document
Praaning-van Dalen, D.P. (author), Brouwer, A. (author), Knook, D.L. (author), Instituut voor experimentele gerontologie TNO (author)
The clearance of five radioactively labeled test substances - polyvinylpyrrolidone, colloidal albumin, antimony sulfur colloid, endotoxin, and heparin - by the reticuloendothelial system was studied after i.v. injection of these substances into rats. The participation of parenchymal, Kupffer, and endothelial liver cells could be determined after...
article 1981
document
Seifert, W.F. (author), Bosma, A. (author), Brouwer, A. (author), Hendriks, H.F.J. (author), Roholl, P.J.M. (author), van Leeuwen, R.E.W. (author), de Thiel van-Ruiter, G.C.F. (author), Seifert-Bock, I. (author), Knook, D.L. (author), TNO Preventie en Gezondheid (author)
Earlier studies have shown that retinoid administration suppresses the generation of hepatic fibrosis and stimulates its regression in normal (i.e., vitamin A-sufficient) carbon tetrachloride-treated rats. This study focuses on the possible role of a marginal or deficient vitamin A status on carbon tetrachloride-induced fibrosis. This...
article 1994
document
Praaning-Van Dalen, D.P. (author), Brouwer, A. (author), Knook, D.L. (author)
article 1982
document
Wijlhuizen, G.J. (author), Hopman-Rock, M. (author), Knook, D.L. (author), van der Cammen, T.J. (author), TNO Kwaliteit van Leven (author)
article 2006
document
Heijmans, B.T. (author), Westendorp, R.G.J. (author), Knook, D.L. (author), Kluft, C. (author), Slagboom, P.E. (author), Gaubius instituut TNO (author)
OBJECTIVES: We studied the contribution of putative risk genotypes at the angiotensin I-converting enzyme inhibitor (ACE D/D) and plasminogen activator inhibitor-1 (PAI-1 4G/4G) loci to all-cause and cardiovascular mortality in a population-based cohort. BACKGROUND: The ACE D/D and PAI-1 4G/4G genotypes have been consistently associated with...
article 1999
document
Wolthuis, O.L. (author), Knook, D.L. (author), Nickolson, V.J. (author), Medisch Biologisch Laboratorium TNO (author)
Spontaneous motor activity and physically undemanding conditioned suppression of drinking behavior were assessed in rats of 3, 12, 18 or 30 months (M) age. Initial spontaneous motor activity of 12 M rats was as low as that of 30 M rats and both were significantly lower than that of 3 M rats. The performance of 3, 12 and 18 M rats were similar to...
article 1976
document
van Buuren, S. (author), Boshuizen, H.C. (author), Knook, D.L. (author), TNO Preventie en Gezondheid (author)
This paper studies a non-response problem in survival analysis where the occurrence of missing data in the risk factor is related to mortality. In a study to determine the influence of blood pressure on survival in the very old (85+ years), blood pressure measurements are missing in about 12.5 per cent of the sample. The available data suggest...
article 1999
document
de Boer, M. (author), Pingen, G. (author), Knook, D. (author), Schutte, K. (author), Kraaij, W. (author)
In content based video retrieval videos are often indexed with semantic labels (concepts) using pre-trained classifiers. These pre-trained classifiers (concept detectors), are not perfect, and thus the labels are noisy. Additionally, the amount of pre-trained classifiers is limited. Often automatic methods cannot represent the query adequately...
article 2017
Searched for: +
(1 - 20 of 28)

Pages