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Blom, W.M. (author), van Dijk, L.M. (author), Michelsen-Huisman, A. (author), Houben, G.F. (author), Knulst, A.C. (author), Linders, Y.F.M. (author), Verhoeckc, K.C.M. (author), Holleman, B.C. (author), Lentz, L.R. (author)
Background: Allergen information on product labels is crucial in food allergy management, though inadequacy in current labelling practices is one of the major causes for accidental reactions upon consuming prepacked food products. Objective: This study analyses current status of communicating allergen information on food labels and provides...
article 2021
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Smits, M. (author), Nooijen, I. (author), Redegeld, F. (author), de Jong, A. (author), Le, T.M. (author), Knulst, A. (author), Houben, G.F. (author), Verhoeckc, K.C.M. (author)
Scope: No accepted and validated methods are currently available which can accurately predict protein allergenicity. In this study, the role of digestion and transport on protein allergenicity is investigated. Methods and results: Peanut allergens (Ara h 1, 2, 3, and 6) and a milk allergen (β-lactoglobulin) are transported across pig intestinal...
article 2021
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Houben, A.J.P. (author), Goldberg, T. (author), Slomp, C.P. (author)
The Toarcian Oceanic Anoxic Event (T-OAE, ~183 Ma) represents a well-known episode of organic-rich deposition, which is accompanied by a substantial negative carbon-isotope excursion (CIE). Underpinning the relationships between the carbon-cycle perturbation, ocean anoxia, primary productivity feedbacks and the enrichment of sedimentary organic...
article 2021
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Meima, M.Y. (author), Blom, W.M. (author), Westerhout, J. (author), Kruizinga, A.G. (author), Remington, B.C. (author), Wheeler, M.W. (author), Houben, G.F. (author)
article 2021
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Remington, B.C. (author), Westerhout, J. (author), Meima, M.Y. (author), Blom, W.M. (author), Kruizinga, A.G. (author), Wheeler, M.W. (author), Taylor, S.L. (author), Houben, G.F. (author), Baumert, J.L. (author)
Food allergy and allergen management are important global public health issues. In 2011, the first iteration of our allergen threshold database (ATDB) was established based on individual NOAELs and LOAELs from oral food challenge in roughly 1750 allergic individuals. Population minimal eliciting dose (EDp) distributions based on this dataset...
article 2020
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Pennings, H.J.M. (author), Oprins, E.A.P.B. (author), Wittenberg, H. (author), Houben, M.M.J. (author), Groen, E.L. (author)
BACKGROUND: Spatial disorientation (SD) remains a significant cause of accidents and near accidents. A variety of training methods have been used to assist pilots to anticipate the SD problem. The value of such training in the prevention of disorientation has been difficult to assess.METHODS: To study transfer of SD awareness training, we...
article 2020
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Madsen, C.B. (author), van den Dungen, M.W. (author), Cochrane, S. (author), Houben, G.F. (author), Knibb, R.C. (author), Knulst, A.C. (author), Ronsmans, S. (author), Yarham, R.A.R. (author), Schnadt, S. (author), Turner, P.J. (author), Baumert, J. (author), Cavandoli, E. (author), Chan, C.H. (author), Warner, A. (author), Crevel, R.W.R. (author)
Substantial progress has been made in characterising the risk associated with exposure to allergens in food. However, absence of agreement on what risk is tolerable has made it difficult to set quantitative limits to manage that risk and protect allergic consumers effectively. This paper reviews scientific progress in the area and the diverse...
article 2020
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Versteegh, G.J.M. (author), Houben, A.J.P. (author), Zonneveld, K.A.F. (author)
Anoxic sediments, as compared to oxic settings, encompass a much higher proportion of relatively labile and thus more reactive organic matter, naturally giving rise to structural changes of the organic molecules themselves, as well as cross-linking between them (e.g., through reactive sulfur species). Both processes transform the original...
article 2020
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Cramwinckel, M.J. (author), Coxall, H.K. (author), Sliwinska, K.K. (author), Polling, M. (author), Harper, D.T. (author), Bijl, P.K. (author), Brinkhuis, H. (author), Eldrett, J.S. (author), Houben, A.J.P. (author), Peterse, F. (author), Schhouten, S. (author), Reichart, G.J. (author), Zachos, J.C. (author), Sluijs, A. (author)
Several studies indicate that North Atlantic Deep Water (NADW) formation might have initiated during the globally warm Eocene (56–34 Ma). However, constraints on Eocene surface ocean conditions in source regions presently conducive to deep water formation are sparse. Here we test whether ocean conditions of the middle Eocene Labrador Sea might...
article 2020
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Blom, W.M. (author), van Os-Medendorp, H. (author), Bijlsma, S. (author), van Dijk, A. (author), Kruizinga, A.G. (author), Rubingh, C. (author), Michelsen-Huisman, A.D. (author), Knulst, A.C. (author), Houben, G.F. (author)
Unintentional intake of allergens through food products poses a daily risk for allergic patients. Models estimating the risk of reactions mostly use intake data from general population surveys. Our study evaluates the comparability of food intake levels in the general population to those in the food allergic population. Data were collected by a...
article 2020
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Verhoeckx, K. (author), lindholm Bøgh, K. (author), Constable, A. (author), Epstein, M.M. (author), hoffmann Sommergruber, K. (author), Holzhauser, T. (author), Houben, G. (author), Kuehn, A. (author), Roggen, E. (author), O'Mahony, L. (author), Remington, B. (author), Crevel, R. (author)
The growing world population and increased pressure on agricultural resources are driving a shortage of dietary protein sources. As a result, industry is developing more sustainable novel food protein sources such as insects, algae and duckweed and using new processing techniques. Consumer exposure to these novel or processed proteins, could...
article 2020
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Houben, G.F. (author), Baumert, J.L. (author), Blom, W.M. (author), Kruizinga, A.G. (author), Meima, M.Y. (author), Remington, B.C. (author), Wheeler, M.W. (author), Westerhout, J. (author), Taylor, S.L. (author)
Previously, we published selected Eliciting Dose (ED) values (i.e. ED01 and ED05 values) for 14 allergenic foods, predicted to elicit objective allergic symptoms in 1% and 5%, respectively, of the allergic population (Remington et al., 2020). These ED01 and ED05 values were specifically presented and discussed in the context of establishing...
article 2020
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Houben, J. (author), Sögütoglu, L.C. (author), Donkers, P. (author), Huinink, H. (author), Adan, O.C.G. (author)
Potassium carbonate, K2CO3, has been identified as one of the most promising thermochemical storagematerials for the built environment. Where a lot of knowledge has been gained on hydration/dehydrationbehavior at atmospheric (open system) conditions, little is known of this process under pure water vaporconditions (closed vacuum system). In this...
article 2020
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Houben, A.J.P. (author), Bijl, P.K. (author), Sluijs, A. (author), Schouten, S. (author), Brinkhuis, H. (author)
During the Eocene‐Oligocene Transition (EOT; 34–33.5 Ma), Antarctic ice sheets relatively rapidly expanded, leading to the first continent‐scale glaciation of the Cenozoic. Declining atmospheric CO2 concentrations and associated feedbacks have been invoked as underlying mechanisms, but the role of the quasi‐coeval opening of Southern Ocean...
article 2019
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Schollhorn, I. (author), Houben, A.J.P. (author), Gertsch, B. (author), Adatte, T. (author), Alexey, U. (author), de Kaenel, E. (author), Spangenberg, J.E. (author), Janssen, N. (author), Schwennicke, T. (author), Follmi, K.B. (author)
The late Oligocene–early Miocene interval records a discernable episode of phosphorite formation, which is considered as the first of four main phosphogenic episodes during the late early and late Cenozoic. In order to better constrain the processes leading to widespread phosphorite formation we present new radiometric, geochemical,...
article 2019
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Westerhout, J. (author), Baumert, J.L. (author), Blom, W.M. (author), Allen, K.J. (author), Ballmer-Weber, B. (author), Crevel, R.W.R. (author), Dubois, A.E.J. (author), Fernández-Rivas, M. (author), Greenhawt, M.J. (author), Hourihane, J.O. (author), Koplin, J.J. (author), Kruizinga, A.G. (author), Le, T.M. (author), Sampson, H.A. (author), Shreffler, W.G. (author), Turner, P.J. (author), Taylor, S.L. (author), Houben, G.F. (author), Remington, B.C. (author)
Background: Food allergies are a significant public health issue, and the only effective management option currently available is strict avoidance of all foods containing the allergen. In view of the practical impossibility of limiting risks to zero, quantitative allergen risk assessment and management strategies are needed. Objective: We sought...
article 2019
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Shkatulov, A.I. (author), Houben, J. (author), Fischer, H. (author), Huinink, H.P. (author)
Thermochemical energy storage (TCES) is an emerging technology promising for domestic applications. Recently, K2CO3 was identified and studied as a TCES material. In this work, the composite “K2CO3 in expanded vermiculite” (69 wt. % of the salt) was prepared and studied for thermochemical energy storage bearing in mind its application for space...
article 2019
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van de Schootbrugge, B. (author), Houben, A.J.P. (author), Ercan, F.E.Z. (author), Verreussel, R. (author), Kerstholt, S. (author), Janssen, N.M.M. (author), Nikitenko, B. (author), Suan, G. (author)
The Toarcian Oceanic Anoxic Event (T-OAE, c. 182 Ma) represents a major perturbation of the carbon cycle marked by widespread black shale deposition. Consequently, the onset of the T-OAE has been linked to the combined effects of global warming, high productivity, basin restriction and salinity stratification. However, the processes that led to...
article 2019
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Sogütoglu, L.C. (author), Steiger, M. (author), Houben, J. (author), Biemans, D. (author), Fischer, H.R. (author), Donkers, P.A.J. (author), Huinink, H. (author), Adan, O.C.G. (author)
The solid-state hydration of salts has gained particular interest within the frame of thermochemical energy storage. In this work, the water vapor pressure-temperature (p-T) phase diagram of the following thermochemical salts was constructed by combining equilibrium and nonequilibrium hydration experiments: CuCl 2 , K 2 CO 3 , MgCl 2 ·4H 2 O,...
article 2019
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Bos, J.E. (author), van den Berg-Kroon, E.C.M. (author), Houben, M.M.J. (author), Kuiper, O.X. (author)
Car handling, and hence, safety, is affected by the way we estimate speed. Speed, however, is often underestimated in degraded visual environments, including virtual environments such as driving simulators. In simulators the visual and physical motion are typically incongruent as limited by quality and amplitude, respectively, which may cause a...
article 2019
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