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Stroek, K. (author), Heijboer, A.C. (author), van Veen-Sijne, M. (author), Bosch, A.M. (author), Ploeg C.P.B. van der, (author), Zwaveling-Soonawala, N. (author), de Jonge, R. (author), van Trotsenburg, A.S.P. (author), Boelen, A. (author)
Introduction: Newborn screening (NBS) for congenital hypothyroidism (CH) in the Netherlands consists of thyroxine (T4), thyroid-stimulating hormone (TSH), and T4-binding globulin (TBG) measurements to detect thyroidal CH and central CH (CH-C). CH-C is detected by T4 or a calculated T4/TBG ratio, which serves as an indirect measure of free T4....
article 2021
document
Stroek, K. (author), Heijboer, A.C. (author), Bouva, M.J. (author), van der Ploeg, C.P.B. (author), Heijnen, M.L.A. (author), Weijman, G. (author), Bosch, A.M. (author), de Jonge, R. (author), Schielen, P.C.J.I. (author), van Trotsenburg, A.S.P. (author), Boelen, A. (author)
Objective: Congenital hypothyroidism (CH) is defined as thyroid hormone deficiency at birth due to disorders of the thyroid gland (thyroidal CH, CH-T), or the hypothalamus or pituitary (central CH, CH-C). The Dutch Newborn Screening (NBS) strategy is primarily based on determination of thyroxine (T4) concentrations in dried blood spots followed,...
article 2020
document
Ageron, M. (author), Aiello, S. (author), Ameli, F. (author), Andre, M. (author), Androulakis, G. (author), Anghinolfi, M. (author), Anton, G. (author), Ardid, M. (author), Aublin, J. (author), Bagatelas, C. (author), Barbarino, G. (author), Baret, B. (author), Pree, S.B. (author), Belias, A. (author), Berbee, E. (author), van den Berg, A.M. (author), Bertin, V. (author), van Beveren, V. (author), Biagi, S. (author), Biagioni, A. (author), Bianucci, S. (author), Billault, M. (author), Bissinger, M. (author), de Boer, R. (author), Boumaaza, J. (author), Bourret, S. (author), Bouta, M. (author), Bouwhuis, M. (author), Bozza, C. (author), Brânzaş, H. (author), Briel, M. (author), Bruchner, M. (author), Bruijn, R. (author), Brunner, J. (author), Buis, E.J. (author), Buompane, R. (author), Busto, J. (author), Cacopardo, G. (author), Caillat, L. (author), Calì, C. (author), Calvo, D. (author), Capone, A. (author), Celli, S. (author), Chabab, M. (author), Chau, N. (author), Cherubini, S. (author), Chiarella, V. (author), Chiarusi, T. (author), Circella, M. (author), Cocimano, R. (author), Coelho, J.A.B. (author), Coleiro, A. (author), Molla, M.C. (author), Colonges, S. (author), Coniglione, R. (author), Cosquer, A. (author), Coyle, P. (author), Creusot, A. (author), Cuttone, G. (author), D’Amato, C. (author), D’Amico, A. (author), D’Onofrio, A. (author), Dallier, R. (author), de Palma, M. (author), de Sio, C. (author), di Palma, I. (author), Díaz, A.F. (author), Diego-Tortosa, D. (author), Distefano, C. (author), Domi, A. (author), Donà, R. (author), Donzaud, C. (author), van Dooren, L. (author), Dornic, D. (author), Dörr, M. (author), Durocher, M. (author), Eberl, T. (author), van Eeden, T. (author), Bojaddaini, I.E. (author), Eljarrari, H. (author), Elsaesser, D. (author), Enzenhöfer, A. (author), Fermani, P. (author), Ferrara, G. (author), Filipović, M.D. (author), Fusco, L.A. (author), Gajanana, D. (author), Gal, T. (author), Soto, A.G. (author), Garufi, F. (author), Gialanella, L. (author), Giorgio, E. (author), Giuliante, A. (author), Gozzini, S.R. (author), Gracia, R. (author), Graf, K. (author), Grasso, D. (author), Grégoire, T. (author), Grella, G. (author), Grimaldi, A. (author), Grmek, A. (author), Guderian, D. (author), Guerzoni, M. (author), Guidi, C. (author), Hallmann, S. (author), Hamdaoui, H. (author), van Haren, H. (author), Heijboer, A. (author), Hekalo, A. (author), Henry, S. (author), Hernández-Rey, J.J. (author), Hofestädt, J. (author), Huang, F. (author), Santiago, E.H. (author), Illuminati, G. (author), James, C.W. (author), Jansweijer, P. (author), Jongen, M. (author), de Jong, M. (author), de Jong, P. (author), Kadler, M. (author), Kalaczyński, P. (author), Kalekin, O. (author), Katz, U.F. (author), Kayzel, F. (author), Keller, P. (author), Chowdhury, N.R.K. (author), van der Knaap, F. (author), Koffeman, E.N. (author), Kooijman, P. (author), Koopstra, J. (author), Kouchner, A. (author), Kreter, M. (author), Kulikovskiy, V. (author), Meghna, K.K. (author), Lahmann, R. (author), Lamare, P. (author), Larosa, G. (author), Laurence, J. (author), le Breton, R. (author), Leone, F. (author), Leonora, E. (author), Levi, G. (author), Librizzi, F. (author), Lincetto, M. (author), Litrico, P. (author), Alvarez, C.D.L. (author), Lonardo, A. (author), Longhitano, F. (author), Lopez-Coto, D. (author), Maggi, G. (author), Mańczak, J. (author), Mannheim, K. (author), Margiotta, A. (author), Marinelli, A. (author), Markou, C. (author), Martin, L. (author), Martínez-Mora, J.A. (author), Martini, A. (author), Marzaioli, F. (author), Mele, R. (author), Melis, K.W. (author), Migliozzi, P. (author), Migneco, E. (author), Mijakowski, P. (author), Miranda, L.S. (author), Mollo, C.M. (author), Mongelli, M. (author), Morganti, M. (author), Moser, M. (author), Moussa, A. (author), Muller, R. (author), Musico, P. (author), Musumeci, M. (author), Nauta, L. (author), Navas, S. (author), Nicolau, C.A. (author), Nielsen, C. (author), Ó Fearraigh, B. (author), Organokov, M. (author), Orlando, A. (author), Panagopoulos, V. (author), Pancaldi, G. (author), Papalashvili, G. (author), Papaleo, R. (author), Pastore, C. (author), Păvălaş, G.E. (author), Pellegrini, G. (author), Pellegrino, C. (author), Perrin-Terrin, M. (author), Piattelli, P. (author), Pikounis, K. (author), Pisanti, O. (author), Poirè, C. (author), Polydefki, G. (author), Popa, V. (author), Post, M. (author), Pradier, T. (author), Pühlhofer, G. (author), Pulvirenti, S. (author), Quinn, L. (author), Raffaelli, F. (author), Randazzo, N. (author), Rapicavoli, A. (author), Razzaque, S. (author), Real, D. (author), Reck, S. (author), Reubelt, J. (author), Riccobene, G. (author), Rigalleau, L. (author), Rizza, G. (author), Rocco, R. (author), Rovelli, A. (author), Royon, J. (author), Salemi, M. (author), Salvadori, I. (author), Samtleben, D.F.E. (author), Sánchez Losa, A. (author), Sanguineti, M. (author), Santangelo, A. (author), Santonocito, D. (author), Sapienza, P. (author), Schmelling, J. (author), Sciacca, V. (author), Sciliberto, D. (author), Seneca, J. (author), Sgura, I. (author), Shanidze, R. (author), Sharma, A. (author), Simeone, F. (author), Sinopoulou, A. (author), Spisso, B. (author), Spurio, M. (author), Stavropoulos, D. (author), Steijger, J. (author), Stellacci, S.M. (author), Strandberg, B. (author), Stransky, D. (author), Stüven, T. (author), Taiuti, M. (author), Tayalati, Y. (author), Tenllado, E. (author), Tézier, D. (author), Thakore, T. (author), Theraube, S. (author), Timmer, P. (author), Tingay, S. (author), Trovato, A. (author), Tsagkli, S. (author), Tzamariudaki, E. (author), Tzanetatos, D. (author), Valieri, C. (author), van Elewyck, V. (author), Versari, F. (author), Viola, S. (author), Vivolo, D. (author), de Wasseige, G. (author), Wilms, J. (author), Wojaczyński, R. (author), de Wolf, E. (author), Zaborov, D. (author), Zegarelli, A. (author), Zornoza, J.D. (author), Zuniga, J. (author)
KM3NeT is a research infrastructure located in the Mediterranean Sea, that will consist of two deep-sea Cherenkov neutrino detectors. With one detector (ARCA), the KM3NeT Collaboration aims at identifying and studying TeV–PeV astrophysical neutrino sources. With the other detector (ORCA), the neutrino mass ordering will be determined by studying...
article 2020
document
Aiello, S. (author), Ameli, F. (author), Andre, M. (author), Androulakis, G. (author), Anghinolfi, M. (author), Anton, G. (author), Ardid, M. (author), Aublin, J. (author), Bagatelas, C. (author), Barbarino, G. (author), Baret, B. (author), du Pree, S.B. (author), Bendahman, M. (author), Berbee, E. (author), van den Berg, A.M. (author), Bertin, V. (author), van Beveren, V. (author), Biagi, S. (author), Biagioni, A. (author), Bissinger, M. (author), Boumaaza, J. (author), Bourret, S. (author), Bouta, M. (author), Bouvet, G. (author), Bouwhuis, M. (author), Bozza, C. (author), Brânzaş, H. (author), Bruchner, M. (author), Bruijn, R. (author), Brunner, J. (author), Buis, E. (author), Buompane, R. (author), Busto, J. (author), Calvo, D. (author), Capone, A. (author), Celli, S. (author), Chabab, M. (author), Chau, N. (author), Cherubini, S. (author), Chiarella, V. (author), Chiarusi, T. (author), Circella, M. (author), Cocimano, R. (author), Coelho, J.A.B. (author), Coleiro, A. (author), Molla, M.C. (author), Colonges, S. (author), Coniglione, R. (author), Coyle, P. (author), Creusot, A. (author), Cuttone, G. (author), D'Onofrio, A. (author), Dallier, R. (author), de Palma, M. (author), di Palma, I. (author), Diaz, A.F. (author), Diego-Tortosa, D. (author), Distefano, C. (author), Domi, A. (author), Dona, R. (author), Donzaud, C. (author), Dornic, D. (author), Dorr, M. (author), Durocher, M. (author), Eberl, T. (author), el Bojaddaini, I. (author), Eljarrari, H. (author), Elsaesser, D. (author), Enzenhofer, A. (author), Fermani, P. (author), Ferrara, G. (author), Filipović, M.D. (author), Franco, A. (author), Fusco, L.A. (author), Gal, T. (author), Soto, A.G. (author), Garufi, F. (author), Gialanella, L. (author), Giorgio, E. (author), Gozzini, S.R. (author), Gracia, R. (author), Graf, K. (author), Grasso, D. (author), Gregoire, T. (author), Grella, G. (author), Guderian, D. (author), Guidi, C. (author), Hallmann, S. (author), Hamdaoui, H. (author), van Haren, H. (author), Heijboer, A. (author), Hekalo, A. (author), Hernández-Rey, J.J. (author), Hofestadt, J. (author), Huang, F. (author), Illuminati, G. (author), James, C.W. (author), Jansweijer, P. (author), de Jong, M. (author), de Jong, P. (author), Kadler, M. (author), Kalaczynski, P. (author), Kalekin, O. (author), Katz, U.F. (author), Chowdhury, N.R.K. (author), van der Knaap, F.G.P. (author), Koffeman, E.N. (author), Kooijman, P. (author), Kouchner, A. (author), Kulikovskiy, V. (author), Lahmann, R. (author), Larosa, G. (author), le Breton, R. (author), Leone, F. (author), Leonora, E. (author), Levi, G. (author), Lincetto, M. (author), Clark, M.L. (author), Lonardo, A. (author), Longhitano, F. (author), Lopez-Coto, D. (author), Maggi, G. (author), Manczak, J. (author), Mannheim, K. (author), Margiotta, A. (author), Marinelli, A. (author), Markou, C. (author), Martignac, G. (author), Martin, L. (author), Martinez-Mora, J.A. (author), Martini, A. (author), Marzaioli, F. (author), Mazzou, S. (author), Mele, R. (author), Melis, K.W. (author), Migliozzi, P. (author), Migneco, E. (author), Mijakowski, P. (author), Miranda, L.S. (author), Mollo, C.M. (author), Morganti, M. (author), Moser, M. (author), Moussa, A. (author), Muller, R. (author), Musumeci, M. (author), Nauta, L. (author), Navas, S. (author), Nicolau, C.A. (author), Nielsen, C. (author), Ó Fearraigh, B. (author), Organokov, M. (author), Orlando, A. (author), Panagopoulos, V. (author), Papalashvili, G. (author), Papaleo, R. (author), Pastore, C. (author), Păvălaş, G.E. (author), Pellegrino, C. (author), Perrin-Terrin, M. (author), Piattelli, P. (author), Pieterse, C. (author), Pikounis, K. (author), Pisanti, O. (author), Poire, C. (author), Polydefki, G. (author), Popa, V. (author), Post, M. (author), Pradier, T. (author), Pühlhofer, G. (author), Pulvirenti, S. (author), Quinn, L. (author), Raffaelli, F. (author), Randazzo, N. (author), Rapicavoli, A. (author), Razzaque, S. (author), Real, D. (author), Reck, S. (author), Reubelt, J. (author), Riccobene, G. (author), Richer, M. (author), Rigalleau, L. (author), Rovelli, A. (author), Salvadori, I. (author), Samtleben, D.F.E. (author), Sánchez Losa, A. (author), Sanguineti, M. (author), Santangelo, A. (author), Santonocito, D. (author), Sapienza, P. (author), Schnabel, J. (author), Sciacca, V. (author), Seneca, J. (author), Sgura, I. (author), Shanidze, R. (author), Sharma, A. (author), Simeone, F. (author), Sinopoulou, A. (author), Spisso, B. (author), Spurio, M. (author), Stavropoulos, D. (author), Steijger, J. (author), Stellacci, S.M. (author), Strandberg, B. (author), Stransky, D. (author), Taiuti, M. (author), Tayalati, Y. (author), Tenllado, E. (author), Thakore, T. (author), Tingay, S. (author), Tzamariudaki, E. (author), Tzanetatos, D. (author), van Elewyck, V. (author), Vannoye, G. (author), Versari, F. (author), Viola, S. (author), Vivolo, D. (author), de Wasseige, G. (author), Wilms, J. (author), Wojaczynski, R. (author), de Wolf, E. (author), Zaborov, D. (author), Zegarelli, A. (author), Zornoza, J.D. (author), Zúñiga, J. (author)
The KM3NeT Collaboration runs a multi-site neutrino observatory in the Mediterranean Sea. Water Cherenkov particle detectors, deep in the sea and far off the coasts of France and Italy, are already taking data while incremental construction progresses. Data Acquisition Control software is operating off-shore detectors as well as testing and...
article 2020
document
Aiello, S. (author), Akrame, S.E. (author), Ameli, F. (author), Anassontzis, E.G. (author), Andre, M. (author), Androulakis, G. (author), Anghinolfi, M. (author), Anton, G. (author), Ardid, M. (author), Aublin, J. (author), Avgitas, T. (author), Baars, M. (author), Bagatelas, C. (author), Barbarino, G. (author), Baret, B. (author), Barrios-Martí, J. (author), Belias, A. (author), Berbee, E. (author), Berg, A.V.D. (author), Bertin, V. (author), Biagi, S. (author), Biagioni, A. (author), Biernoth, C. (author), Bormuth, R. (author), Boumaaza, J. (author), Bourret, S. (author), Bouwhuis, M. (author), Bozza, C. (author), Branzaş, H. (author), Briukhanova, N. (author), Bruijn, R. (author), Brunner, J. (author), Buis, E.J. (author), Buompane, R. (author), Busto, J. (author), Calvo, D. (author), Capone, A. (author), Caramete, L. (author), Celli, S. (author), Chabab, M. (author), Cherubini, S. (author), Chiarella, V. (author), Chiarusi, T. (author), Circella, M. (author), Cocimano, R. (author), Coelho, J.A.B. (author), Coleiro, A. (author), Molla, M.C. (author), Coniglione, R. (author), Coyle, P. (author), Creusot, A. (author), Cuttone, G. (author), D'Onofrio, A. (author), Dallier, R. (author), Sio, C.D. (author), Palma, I.D. (author), Díaz, A.F. (author), Distefano, C. (author), Domi, A. (author), Donà, R. (author), Donzaud, C. (author), Dornic, D. (author), Dörr, M. (author), Durocher, M. (author), Eberl, T. (author), Eijk, D.V. (author), Bojaddaini, I.E. (author), Elsaesser, D. (author), Enzenhöfer, A. (author), Ferrara, G. (author), Fusco, L.A. (author), Gal, T. (author), Garufi, F. (author), Gauchery, S. (author), Geißelsöder, S. (author), Gialanella, L. (author), Giorgio, E. (author), Giuliante, A. (author), Gozzini, S.R. (author), Ruiz, R.G. (author), Graf, K. (author), Grasso, D. (author), Grégoire, T. (author), Grella, G. (author), Hallmann, S. (author), Haren, H.V. (author), Heid, T. (author), Heijboer, A. (author), Hekalo, A. (author), Hernández-Rey, J.J. (author), Hofestädt, J. (author), Illuminati, G. (author), James, C.W. (author), Jongen, M. (author), Jongewaard, B. (author), de Jong, M. (author), de Jong, P. (author), Kadler, M. (author), Kalaczyński, P. (author), Kalekin, O. (author), Katz, U.F. (author), Chowdhury, N.R.K. (author), Kieft, G. (author), Kießling, D. (author), Koffeman, E.N. (author), Kooijman, P. (author), Kouchner, A. (author), Kreter, M. (author), Kulikovskiy, V. (author), Lahmann, R. (author), Breton, R.L. (author), Leone, F. (author), Leonora, E. (author), Levi, G. (author), Lincetto, M. (author), Lonardo, A. (author), Longhitano, F. (author), Lotze, M. (author), Loucatos, S. (author), Maggi, G. (author), Mańczak, J. (author), Mannheim, K. (author), Margiotta, A. (author), Marinelli, A. (author), Markou, C. (author), Martin, L. (author), Martínez-Mora, J.A. (author), Martini, A. (author), Marzaioli, F. (author), Mele, R. (author), Melis, K.W. (author), Migliozzi, P. (author), Migneco, E. (author), Mijakowski, P. (author), Miranda, L.S. (author), Mollo, C.M. (author), Morganti, M. (author), Moser, M. (author), Moussa, A. (author), Muller, R. (author), Musumeci, M. (author), Nauta, L. (author), Navas, S. (author), Nicolau, C.A. (author), Nielsen, C. (author), Organokov, M. (author), Orlando, A. (author), Panagopoulos, V. (author), Papalashvili, G. (author), Papaleo, R. (author), Pǎvǎlaş, G.E. (author), Pellegrini, G. (author), Pellegrino, C. (author), Pérez Romero, J. (author), Perrin-Terrin, M. (author), Piattelli, P. (author), Pikounis, K. (author), Pisanti, O. (author), Poirè, C. (author), Polydefki, G. (author), Poma, G.E. (author), Popa, V. (author), Post, M. (author), Pradier, T. (author), Pühlhofer, G. (author), Pulvirenti, S. (author), Quinn, L. (author), Raffaelli, F. (author), Randazzo, N. (author), Razzaque, S. (author), Real, D. (author), Resvanis, L. (author), Reubelt, J. (author), Riccobene, G. (author), Richer, M. (author), Rovelli, A. (author), Salvadori, I. (author), Samtleben, D.F.E. (author), Sánchez Losa, A. (author), Sanguineti, M. (author), Santangelo, A. (author), Sapienza, P. (author), Schermer, B. (author), Sciacca, V. (author), Seneca, J. (author), Sgura, I. (author), Shanidze, R. (author), Sharma, A. (author), Simeone, F. (author), Sinopoulou, A. (author), Spisso, B. (author), Spurio, M. (author), Stavropoulos, D. (author), Steijger, J. (author), Stellacci, S.M. (author), Strandberg, B. (author), Stransky, D. (author), Stüven, T. (author), Taiuti, M. (author), Tatone, F. (author), Tayalati, Y. (author), Tenllado, E. (author), Thakore, T. (author), Timmer, P. (author), Trovato, A. (author), Tsagkli, S. (author), Tzamariudaki, E. (author), Tzanetatos, D. (author), Valieri, C. (author), Vallage, B. (author), Elewyck, V.V. (author), Versari, F. (author), Viola, S. (author), Vivolo, D. (author), Volkert, M. (author), de Waardt, L. (author), Wilms, J. (author), de Wolf, E. (author), Zaborov, D. (author), Zornoza, J.D. (author), Zuniga, J. (author)
The Hamamatsu R12199-02 3-inch photomultiplier tube is the photodetector chosen for the first phase of the KM3NeT neutrino telescope. About 7000 photomultipliers have been characterised for dark count rate, timing spread and spurious pulses. The quantum efficiency, the gain and the peak-to-valley ratio have also been measured for a sub-sample in...
article 2018
document
Adrián-Martínez, S. (author), Ageron, M. (author), Aiello, S. (author), Albert, A. (author), Ameli, F. (author), Anassontzis, E.G. (author), Andre, M. (author), Androulakis, G. (author), Anghinolfi, M. (author), Anton, G. (author), Ardid, M. (author), Avgitas, T. (author), Barbarino, G. (author), Barbarito, E. (author), Baret, B. (author), Barrios-Mart, J. (author), Belias, A. (author), Berbee, E. (author), van den Berg, A. (author), Bertin, V. (author), Beurthey, S. (author), van Beveren, V. (author), Beverini, N. (author), Biagi, S. (author), Biagioni, A. (author), Billault, M. (author), Bondì, M. (author), Bormuth, R. (author), Bouhadef, B. (author), Bourlis, G. (author), Bourret, S. (author), Boutonnet, C. (author), Bouwhuis, M. (author), Bozza, C. (author), Bruijn, R. (author), Brunner, J. (author), Buis, E. (author), Buompane, R. (author), Busto, J. (author), Cacopardo, G. (author), Caillat, L. (author), Calamai, M. (author), Calvo, D. (author), Capone, A. (author), Caramete, L. (author), Cecchini, S. (author), Celli, S. (author), Champion, C. (author), Cherubini, S. (author), Chiarella, V. (author), Chiarelli, L. (author), Chiarusi, T. (author), Circella, M. (author), Classen, L. (author), Cobas, D. (author), Cocimano, R. (author), Coelho, J.A.B. (author), Coleiro, A. (author), Colonges, S. (author), Coniglione, R. (author), Cordelli, M. (author), Cosquer, A. (author), Coyle, P. (author), Creusot, A. (author), Cuttone, G. (author), D’Amato, C. (author), D’Amico, A. (author), D’Onofrio, A. (author), De Bonis, G. (author), De Sio, C. (author), Di Palma, I. (author), Díaz, A.F. (author), Distefano, C. (author), Donzaud, C. (author), Dornic, D. (author), Dorosti-Hasankiadeh, Q. (author), Drakopoulou, E. (author), Drouhin, D. (author), Durocher, M. (author), Eberl, T. (author), Eichie, S. (author), van Eijk, D. (author), El Bojaddaini, I. (author), Elsaesser, D. (author), Enzenhöfer, A. (author), Favaro, M. (author), Fermani, P. (author), Ferrara, G. (author), Frascadore, G. (author), Furini, M. (author), Fusco, L.A. (author), Gal, T. (author), Galatà, S. (author), Garufi, F. (author), Gay, P. (author), Gebyehu, M. (author), Giacomini, F. (author), Gialanella, L. (author), Giordano, V. (author), Gizani, N. (author), Gracia, R. (author), Graf, K. (author), Grégoire, T. (author), Grella, G. (author), Grmek, A. (author), Guerzoni, M. (author), Habel, R. (author), Hallmann, S. (author), van Haren, H. (author), Harissopulos, S. (author), Heid, T. (author), Heijboer, A. (author), Heine, E. (author), Henry, S. (author), Hernández-Rey, J.J. (author), Hevinga, M. (author), Hofestädt, J. (author), Hugon, C.M.F. (author), Illuminati, G. (author), James, C.W. (author), Jansweijerf, P. (author), Jongen, M. (author), de Jong, M. (author), Kadler, M. (author), Kalekin, O. (author), Kappes, A. (author), Katz, U.F. (author), Keller, P. (author), Kieft, G. (author), Kießling, D. (author), Koffeman, E.N. (author), Kooijman, P. (author), Kouchner, A. (author), Kreter, M. (author), Kulikovskiy, V. (author), Lahmann, R. (author), Lamare, P. (author), Larosa, G. (author), Leisos, A. (author), Leone, F. (author), Leonora, E. (author), Lindsey Clark, M. (author), Liolios, A. (author), Llorens Alvarez, C.D. (author), Lo Presti, D. (author), Löhner, H. (author), Lonardo, A. (author), Lotze, M. (author), Loucatos, S. (author), Maccioni, E. (author), Mannheim, K. (author), Manzali, M. (author), Margiotta, A. (author), Margotti, A. (author), Marinelli, A. (author), Maris, O. (author), Markou, C. (author), Martínez-Mora, J.A. (author), Martini, A. (author), Marzaioli, F. (author), Mele, R. (author), Melis, K.W. (author), Michael, T. (author), Migliozzi, P. (author), Migneco, E. (author), Mijakowski, P. (author), Miraglia, A. (author), Mollo, C.M. (author), Mongelli, M. (author), Morganti, M. (author), Moussa, A. (author), Musico, P. (author), Musumeci, M. (author), Navas, S. (author), Nicolau, C.A. (author), Olcina, I. (author), Olivetto, C. (author), Orlando, A. (author), Orzelli, A. (author), Pancaldi, G. (author), Papaikonomou, A. (author), Papaleo, R. (author), Păvălas, G.E. (author), Peek, H. (author), Pellegrini, G. (author), Pellegrino, C. (author), Perrina, C. (author), Pfutzner, M. (author), Piattelli, P. (author), Pikounis, K. (author), Pleinert, M.O. (author), Poma, G.E. (author), Popa, V. (author), Pradier, T. (author), Pratolongo, F. (author), Pühlhofer, G. (author), Pulvirenti, S. (author), Quinn, L. (author), Racca, C. (author), Raffaelli, F. (author), Randazzo, N. (author), Rauch, T. (author), Real, D. (author), Resvanis, L. (author), Reubelt, J. (author), Riccobene, G. (author), Rossi, C. (author), Rovelli, A. (author), Saldaña, M. (author), Salvadori, I. (author), Samtleben, D.F.E. (author), Sánchez García, A. (author), Sánchez Losa, A. (author), Sanguineti, M. (author), Santangelo, A. (author), Santonocito, D. (author), Sapienza, P. (author), Schimmel, F. (author), Schmelling, J. (author), Schnabel, J. (author), Sciacca, V. (author), Sedita, M. (author), Seitz, T. (author), Sgura, I. (author), Simeone, F. (author), Sipala, V. (author), Spisso, B. (author), Spurio, M. (author), Stavropoulos, G. (author), Steijger, J. (author), Stellacci, S.M. (author), Stransky, D. (author), Taiuti, M. (author), Tayalati, Y. (author), Terrasi, F. (author), Tézier, D. (author), Theraube, S. (author), Timmer, P. (author), Tönnis, C. (author), Trasatti, L. (author), Travaglini, R. (author), Trovato, A. (author), Tsirigotis, A. (author), Tzamarias, S. (author), Tzamariudaki, E. (author), Vallage, B. (author), van Elewyck, V. (author), Vermeulen, J. (author), Versari, F. (author), Vicini, P. (author), Viola, S. (author), Vivolo, D. (author), Volkert, M. (author), Wiggers, L. (author), Wilms, J. (author), de Wolf, E. (author), Zachariadou, K. (author), Zani, S. (author), Zornoza, J.D. (author), Zúñiga, J. (author), The KM3NeT collaboration (author)
Studying atmospheric neutrino oscillations in the few-GeV range with a multi-megaton detector promises to determine the neutrino mass hierarchy. This is the main science goal pursued by the future KM3NeT/ORCA water Cherenkov detector in the Mediterranean Sea. In this paper, the processes that limit the obtainable resolution in both energy and...
article 2017
document
Adrián-Martínez, S. (author), Ageron, M. (author), Aharonian, F. (author), Aiello, S. (author), Albert, A. (author), Ameli, F. (author), Anassontzis, E. (author), Andre, M. (author), Androulakis, G. (author), Anghinolfi, M. (author), Anton, G. (author), Ardid, M. (author), Avgitas, T. (author), Barbarino, G. (author), Barbarito, E. (author), Baret, B. (author), Barrios-Martí, J. (author), Belhorma, B. (author), Belias, A. (author), Berbee, E. (author), van den Berg, A. (author), Bertin, V. (author), Beurthey, S. (author), van Beveren, V. (author), Beverini, N. (author), Biagi, S. (author), Biagioni, A. (author), Billault, M. (author), Bondì, M. (author), Bormuth, R. (author), Bouhadef, B. (author), Bourlis, G. (author), Bourret, S. (author), Boutonnet, C. (author), Bouwhuis, M. (author), Bozza, C. (author), Bruijn, R. (author), Brunner, J. (author), Buis, E.J. (author), Busto, J. (author), Cacopardo, G. (author), Caillat, L. (author), Calamai, M. (author), Calvo, D. (author), Capone, A. (author), Caramete, L. (author), Cecchini, S. (author), Celli, S. (author), Champion, C. (author), El Moursli, R.C. (author), Cherubini, S. (author), Chiarusi, T. (author), Circella, M. (author), Classen, L. (author), Cocimano, R. (author), Coelho, J.A.B. (author), Coleiro, A. (author), Colonges, S. (author), Coniglione, R. (author), Cordelli, M. (author), Cosquer, A. (author), Coyle, P. (author), Creusot, A. (author), Cuttone, G. (author), D'Amico, A. (author), De Bonis, G. (author), De Rosa, G. (author), De Sio, C. (author), Di Capua, F. (author), Di Palma, I. (author), Díaz García, A.F. (author), Distefano, C. (author), Donzaud, C. (author), Dornic, D. (author), Dorosti-Hasankiadeh, Q. (author), Drakopoulou, E. (author), Drouhin, D. (author), Drury, L. (author), Durocher, M. (author), Eberl, T. (author), Eichie, S. (author), van Eijk, D. (author), El Bojaddaini, I. (author), El Khayati, N. (author), Elsaesser, D. (author), Enzenhöfer, A. (author), Fassi, F. (author), Favali, P. (author), Fermani, P. (author), Ferrara, G. (author), Filippidis, C. (author), Frascadore, G. (author), Fusco, L.A. (author), Gal, T. (author), Galatà, S. (author), Garufi, F. (author), Gay, P. (author), Gebyehu, M. (author), Giordano, V. (author), Gizani, N. (author), Gracia, R. (author), Graf, K. (author), Grégoire, T. (author), Grella, G. (author), Habel, R. (author), Hallmann, S. (author), van Haren, H. (author), Harissopulos, S. (author), Heid, T. (author), Heijboer, A. (author), Heine, E. (author), Henry, S. (author), Hernández-Rey, J.J. (author), Hevinga, M. (author), Hofestädt, J. (author), Hugon, C.M.F. (author), Illuminati, G. (author), James, C.W. (author), Jansweijer, P. (author), Jongen, M. (author), de Jong, M. (author), Kadler, M. (author), Kalekin, O. (author), Kappes, A. (author), Katz, U.F. (author), Keller, P. (author), Kieft, G. (author), Kießling, D. (author), Koffeman, E.N. (author), Kooijman, P. (author), Kouchner, A. (author), Kulikovskiy, V. (author), Lahmann, R. (author), Lamare, P. (author), Leisos, A. (author), Leonora, E. (author), Clark, M.L. (author), Liolios, A. (author), Alvarez, C.D.L. (author), Lo Presti, D. (author), Löhner, H. (author), Lonardo, A. (author), Lotze, M. (author), Loucatos, S. (author), MacCioni, E. (author), Mannheim, K. (author), Margiotta, A. (author), Marinelli, A. (author), Maris, O. (author), Markou, C. (author), Martínez-Mora, J.A. (author), Martini, A. (author), Mele, R. (author), Melis, K.W. (author), Michael, T. (author), Migliozzi, P. (author), Migneco, E. (author), Mijakowski, P. (author), Miraglia, A. (author), Mollo, C.M. (author), Mongelli, M. (author), Morganti, M. (author), Moussa, A. (author), Musico, P. (author), Musumeci, M. (author), Navas, S. (author), Nicolau, C.A. (author), Olcina, I. (author), Olivetto, C. (author), Orlando, A. (author), Papaikonomou, A. (author), Papaleo, R. (author), Pavalas, G.E. (author), Peek, H. (author), Pellegrino, C. (author), Perrina, C. (author), Pfutzner, M. (author), Piattelli, P. (author), Pikounis, K. (author), Poma, G.E. (author), Popa, V. (author), Pradier, T. (author), Pratolongo, F. (author), Pühlhofer, G. (author), Pulvirenti, S. (author), Quinn, L. (author), Racca, C. (author), Raffaelli, F. (author), Randazzo, N. (author), Rapidis, P. (author), Razis, P. (author), Real, D. (author), Resvanis, L. (author), Reubelt, J. (author), Riccobene, G. (author), Rossi, C. (author), Rovelli, A. (author), Saldaña, M. (author), Salvadori, I. (author), Samtleben, D.F.E. (author), García, A.S. (author), Losa, A.S. (author), Sanguineti, M. (author), Santangelo, A. (author), Santonocito, D. (author), Sapienza, P. (author), Schimmel, F. (author), Schmelling, J. (author), Sciacca, V. (author), Sedita, M. (author), Seitz, T. (author), Sgura, I. (author), Simeone, F. (author), Siotis, I. (author), Sipala, V. (author), Spisso, B. (author), Spurio, M. (author), Stavropoulos, G. (author), Steijger, J. (author), Stellacci, S.M. (author), Stransky, D. (author), Taiuti, M. (author), Tayalati, Y. (author), Tézier, D. (author), Theraube, S. (author), Thompson, L. (author), Timmer, P. (author), Tönnis, C. (author), Trasatti, L. (author), Trovato, A. (author), Tsirigotis, A. (author), Tzamarias, S. (author), Tzamariudaki, E. (author), Vallage, B. (author), van Elewyck, V. (author), Vermeulen, J. (author), Vicini, P. (author), Viola, S. (author), Vivolo, D. (author), Volkert, M. (author), Voulgaris, G. (author), Wiggers, L. (author), Wilms, J. (author), De Wolf, E. (author), Zachariadou, K. (author), Zornoza, J.D. (author), Zúñiga, J. (author)
The main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the determination of the mass hierarchy of neutrinos. These objectives are strongly motivated by two recent important discoveries, namely: (1) the high-energy astrophysical neutrino signal...
article 2016
document
Adrián-Martínez, S. (author), Ageron, M. (author), Aiello, S. (author), Albert, A. (author), Ameli, F. (author), Anassontzis, E.G. (author), Andre, M. (author), Androulakis, G. (author), Anghinolfi, M. (author), Anton, G. (author), Ardid, M. (author), Avgitas, T. (author), Barbarino, G. (author), Barbarito, E. (author), Baret, B. (author), Barrios-Martí, J. (author), Belias, A. (author), Berbee, E. (author), van den Berg, A. (author), Bertin, V. (author), Beurthey, S. (author), van Beveren, V. (author), Beverini, N. (author), Biagi, S. (author), Biagioni, A. (author), Billault, M. (author), Bondì, M. (author), Bormuth, R. (author), Bouhadef, B. (author), Bourlis, G. (author), Bourret, S. (author), Boutonnet, C. (author), Bouwhuis, M. (author), Bozza, C. (author), Bruijn, R. (author), Brunner, J. (author), Buis, E.J. (author), Buompane, R. (author), Busto, J. (author), Cacopardo, G. (author), Caillat, L. (author), Calamai, M. (author), Calvo, D. (author), Capone, A. (author), Caramete, L. (author), Cecchini, S. (author), Celli, S. (author), Champion, C. (author), Cherubini, S. (author), Chiarella, V. (author), Chiarelli, L. (author), Chiarusi, T. (author), Circella, M. (author), Classen, L. (author), Cobas, D. (author), Cocimano, R. (author), Coelho, J.A.B. (author), Coleiro, A. (author), Colonges, S. (author), Coniglione, R. (author), Cordelli, M. (author), Cosquer, A. (author), Coyle, P. (author), Creusot, A. (author), Cuttone, G. (author), D'Amato, C. (author), D'Amico, A. (author), D'Onofrio, A. (author), De Bonis, G. (author), De Sio, C. (author), Di Capua, F. (author), Di Palma, I. (author), Distefano, C. (author), Donzaud, C. (author), Dornic, D. (author), Dorosti-Hasankiadeh, Q. (author), Drakopoulou, E. (author), Drouhin, D. (author), Durocher, M. (author), Eberl, T. (author), Eichie, S. (author), van Eijk, D. (author), El Bojaddaini, I. (author), Elsaesser, D. (author), Enzenhöfer, A. (author), Favaro, M. (author), Fermani, P. (author), Ferrara, G. (author), Frascadore, G. (author), Furini, M. (author), Fusco, L.A. (author), Gal, T. (author), Galatà, S. (author), Garufi, F. (author), Gay, P. (author), Gebyehu, M. (author), Giacomini, F. (author), Gialanella, L. (author), Giordano, V. (author), Gizani, N. (author), Gracia, R. (author), Graf, K. (author), Grégoire, T. (author), Grella, G. (author), Grmek, A. (author), Guerzoni, M. (author), Habel, R. (author), Hallmann, S. (author), van Haren, H. (author), Harissopulos, S. (author), Heid, T. (author), Heijboer, A. (author), Heine, E. (author), Henry, S. (author), Hernández-Rey, J.J. (author), Hevinga, M. (author), Hofestädt, J. (author), Hugon, C.M.F. (author), Illuminati, G. (author), James, C.W. (author), Jansweijer, P. (author), Jongen, M. (author), de Jong, M. (author), Kadler, M. (author), Kalekin, O. (author), Kappes, A. (author), Katz, U.F. (author), Keller, P. (author), Kieft, G. (author), Kießling, D. (author), Koffeman, E.N. (author), Kooijman, P. (author), Kouchner, A. (author), Kreter, M. (author), Kulikovskiy, V. (author), Lahmann, R. (author), Lamare, P. (author), Leisos, A. (author), Leonora, E. (author), Clark, M.L. (author), Liolios, A. (author), Alvarez, C.D.L. (author), Lo Presti, D. (author), Löhner, H. (author), Lonardo, A. (author), Lotze, M. (author), Loucatos, S. (author), Maccioni, E. (author), Mannheim, K. (author), Manzali, M. (author), Margiotta, A. (author), Margotti, A. (author), Marinelli, A. (author), Mariš, O. (author), Markou, C. (author), Martínez-Mora, J.A. (author), Martini, A. (author), Marzaioli, F. (author), Mele, R. (author), Melis, K.W. (author), Michael, T. (author), Migliozzi, P. (author), Migneco, E. (author), Mijakowski, P. (author), Miraglia, A. (author), Mollo, C.M. (author), Mongelli, M. (author), Morganti, M. (author), Moussa, A. (author), Musico, P. (author), Musumeci, M. (author), Nicolau, C.A. (author), Olcina, I. (author), Olivetto, C. (author), Orlando, A. (author), Orzelli, A. (author), Pancaldi, G. (author), Paolucci, A. (author), Papaikonomou, A. (author), Papaleo, R. (author), Pǎvǎlaš, G.E. (author), Peek, H. (author), Pellegrini, G. (author), Pellegrino, C. (author), Perrina, C. (author), Pfutzner, M. (author), Piattelli, P. (author), Pikounis, K. (author), Poma, G.E. (author), Popa, V. (author), Pradier, T. (author), Pratolongo, F. (author), Pühlhofer, G. (author), Pulvirenti, S. (author), Quinn, L. (author), Racca, C. (author), Raffaelli, F. (author), Randazzo, N. (author), Real, D. (author), Resvanis, L. (author), Reubelt, J. (author), Riccobene, G. (author), Rossi, C. (author), Rovelli, A. (author), Saldaña, M. (author), Salvadori, I. (author), Samtleben, D.F.E. (author), Sánchez García, A. (author), Sánchez Losa, A. (author), Sanguineti, M. (author), Santangelo, A. (author), Santonocito, D. (author), Sapienza, P. (author), Schimmel, F. (author), Schmelling, J. (author), Schnabel, J. (author), Sciacca, V. (author), Sedita, M. (author), Seitz, T. (author), Sgura, I. (author), Simeone, F. (author), Sipala, V. (author), Spisso, B. (author), Spurio, M. (author), Stavropoulos, G. (author), Steijger, J. (author), Stellacci, S.M. (author), Stransky, D. (author), Taiuti, M. (author), Tayalati, Y. (author), Terrasi, F. (author), Tézier, D. (author), Theraube, S. (author), Timmer, P. (author), Tönnis, C. (author), Trasatti, L. (author), Travaglini, R. (author), Trovato, A. (author), Tsirigotis, A. (author), Tzamarias, S. (author), Tzamariudaki, E. (author), Vallage, B. (author), van Elewyck, V. (author), Vermeulen, J. (author), Versari, F. (author), Vicini, P. (author), Viola, S. (author), Vivolo, D. (author), Volkert, M. (author), Wiggers, L. (author), Wilms, J. (author), de Wolf, E. (author), Zachariadou, K. (author), Zani, S. (author), Zornoza, J.D. (author), Zúñiga, J. (author)
The KM3NeT research infrastructure, currently under construction in the Mediterranean Sea, will host neutrino telescopes for the identification of neutrino sources in the Universe and for studies of the neutrino mass hierarchy. These telescopes will house hundreds of thousands of photomultiplier tubes that will have to be operated in a stable...
article 2016
document
Peters, M. (author), Appel, I.M. (author), Cnossen, M.H. (author), Breuning-Boers, J.M. (author), Heijboer, H. (author), TNO Kwaliteit van Leven (author)
JGZ.
article 2009
document
Peters, M. (author), Appel, I.M. (author), Cnossen, M.H. (author), Breuning-Boers, J.M. (author), Heijboer, H. (author)
Doel Evalueren van de uitkomsten van het eerste jaar na invoering van de uitbreiding van de landelijke hielprikscreening met sikkelcelziekte (SCZ). Opzet Prospectieve landelijke registratie van kinderen met vermoedelijk SCZ of een andere vorm van ernstige hemoglobinopathie. Methode De bloedspots werden geanalyseerd met een...
article 2009
document
Parlevliet, E.T. (author), Heijboer, A.C. (author), Schroder-van der Elst, J.P. (author), Havekes, L.M. (author), Romijn, J.A. (author), Pijl, H. (author), Corssmit, E.P.M. (author), TNO Kwaliteit van Leven (author)
article 2008
document
de Mos, M. (author), van El, B. (author), de Groot, J. (author), Jahr, H. (author), van Schie, H.T.M. (author), van Arkel, E.R. (author), Tol, H. (author), Heijboer, R. (author), van Osch, G.J.V.M. (author), Verhaar, J.A.N. (author), TNO Kwaliteit van Leven (author)
Background: Understanding biochemical and structural changes of the extracellular matrix in Achilles tendinosis might be important for developing mechanism-based therapies. Hypothesis: In Achilles tendinosis, changes occur in biochemical composition and collagen turnover rate. Study Design: Descriptive laboratory study. Methods: From 10 patients...
article 2007
document
Heijboer, A.C. (author), van den Hoek, A.M. (author), Parlevliet, E.T. (author), Havekes, L.M. (author), Romijn, J.A. (author), Pijl, H. (author), Corssmit, E.P.M. (author), TNO Kwaliteit van Leven (author)
Aims/hypothesis: This study was conducted to evaluate the effects of ghrelin on insulin's capacity to suppress endogenous glucose production and promote glucose disposal in mice. To establish whether the growth hormone secretagogue (GHS) receptor can mediate the putative effect of ghrelin on the action of insulin, we also determined the...
article 2006
document
Heijboer, A.C. (author), van den Hoek, A.M. (author), Pijl, H. (author), Voshol, P.J. (author), Havekes, L.M. (author), Romijn, J.A. (author), Corssmit, E.P.M. (author), TNO Kwaliteit van Leven (author)
Aims/hypothesis: The present study was conducted to evaluate the effects of central administration of melanotan II (MTII), a melanocortin-3/4 receptor agonist, on hepatic and whole-body insulin sensitivity, independent of food intake and body weight. Methods: Over a period of 24 h, 225 ng of MTII was injected in three aliquots into the left...
article 2005
document
Heijboer, A.C. (author), Donga, E. (author), Voshol, P.J. (author), Dang, Z.C. (author), Havekes, L.M. (author), Romijn, J.A. (author), Corssmit, E.P.M. (author), TNO Kwaliteit van Leven (author)
Fasting readily induces hepatic steatosis. Hepatic steatosis is associated with hepatic insulin resistance. The purpose of the present study was to document the effects of 16 h of fasting in wild-type mice on insulin sensitivity in liver and skeletal muscle in relation to 1) tissue accumulation of triglycerides (TGs) and 2) changes in mRNA...
article 2005
document
Kater, A.P. (author), Heijboer, H. (author), Peters, M. (author), Vogels, T. (author), Prins, M.H. (author), Heymans, H.S.A. (author)
Objective. To determine the differences in quality of life between children with sickle cell disease and healthy immigrant children. Design. Descriptive, comparative. Method. The quality of life of children with sickle cell disease between 5 and 15 years old being treated in the Emma Children's Hospital AMC in Amsterdam, the Netherlands, was...
article 1999
document
Heijboer, J. (author), Centraal laboratorium TNO (author)
De betekenis van modulus en demping als functie van de temperatuur voor de karakterisering van polymeren, voor hun bruikbaarheid bij diverse temperaturen en voor hun verwerkingsmogelijkheden, wordt beschreven.
article 1966
document
Heijboer, J. (author), Centraal laboratorium TNO (author)
This paper deals with the study of molecular movements in polymers by mechanical measurements. Especially the relation between these movements and the damping is discussed. When the mechanical damping is plotted as a function of frequency several maxima are found; these maxima are absorption bands in the mechanical damping spectrum. For non...
article 1956
document
Heijboer, J. (author), Centraal Laboratorium TNO (author)
article 1956
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