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le Feber, M. (author), Jadoenathmisier, T. (author), Goede, H. (author), Kuijpers, E. (author), Pronk, A. (author)
Will sensor-based exposure assessment be the future in workplace settings? Static instruments with embedded sensors are already applied to monitor levels of dangerous substances-in the context of acute health effects-at critical locations. However, with wearable, lightweight, miniaturized (low-cost) sensors developing quickly, much more is...
article 2021
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Goede, H. (author), Kuijpers, E. (author), Krone, T. (author), le Feber, M. (author), Franken, R. (author), Fransman, W. (author), Duyzer, J. (author), Pronk, A. (author)
This commentary explores the use of high-resolution data from new, miniature sensors to enrich models that predict exposures to chemical substances in the workplace. To optimally apply these sensors, one can expect an increased need for new models that will facilitate the interpretation and extrapolation of the acquired time-resolved data. We...
article 2021
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Spaan, S. (author), Glass, R. (author), Goede, H. (author), Ruiter, S. (author), Gerritsen-Ebben, R.M. (author)
The suitability, availability, and use of protective clothing are critical factors determining the actual dermal exposure (ADE) of operators and workers to pesticides. A realistic assessment of occupational exposure to pesticides requires information about the performance of protective clothing during everyday use. In this study, the performance...
article 2020
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Bakhuys Roozeboom, M.M.C. (author), Huijs, J. (author), van der Beek, D. (author), van Keulen, H. (author), Goede, H. (author), Bouwens, L. (author), van der Meer, L. (author), de Korte, E. (author), van Empelen, P. (author)
Veel gezondheids- en veiligheidsrisico’s op de werkvloer zijn te voorkomen. Dit zou niet alleen de ziektelast in Nederland fors terugdringen, maar tevens voor enorme besparingen zorgen. Bijna een kwart van het ziekteverzuim in Nederland heeft (deels) een werkgerelateerde oorzaak, dit kost vijf miljard euro aan loondoorbetaling per jaar1.
report 2020
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Franken, R.A. (author), Kasiotis, K.M. (author), Tsakirakis, A.N. (author), Chartzela, I. (author), Anastasiadou, P. (author), Fransman, W. (author), Gerritsen-Ebben, R.M. (author), Spaan, S. (author), Goede, H. (author), Machera, K. (author), Gerritsen-Ebben, R. (author)
For many work situations only insufficient exposure data are available to perform proper risk assessment. Because measuring worker exposure can be time consuming and resource intense, the availability of reliable exposure models is important when performing risk assessments. However, the development and improvement of exposure models are...
article 2020
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Goede, H.A. (author), McNally, K. (author), Gorce, J.P. (author), Marquart, H. (author), Warren, N.D. (author), Fransman, W. (author), Tischer, M. (author), Schinkel, J. (author)
This article describes the development of a mechanistic model for underpinning the dermal Advanced REACH Tool (dART), an extension of the existing ART model and its software platform. It was developed for hand exposure to low volatile liquids (vapour pressure ≤ 10 Pa at 20°C) including solids-in-liquid products. The model is based on an existing...
article 2019
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McNally, K. (author), Gorce, J.P. (author), Goede, H.A. (author), Schinkel, J. (author), Warren, N. (author)
The dermal Advanced REACH Tool (dART) is a Tier 2 exposure modelling tool currently in development for estimating dermal exposure to the hands (mg min-1) for non-volatile liquid and solids-in-liquid products. The dART builds upon the existing ART framework and describes three mass transport processes [deposition (Dhands), direct emission and...
article 2019
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Goede, H.A. (author), Ploeg, D. (author), Schinkel, J.M. (author)
The development of a dermal exposure model is a challenge because of the complexity of dermal exposure processes on one hand, and the scarcity of good quality and contextually-rich dermal exposure measurements. Dermal exposure modelling is further complicated by the difficulty of measuring dermal exposure due to the lack of standardised methods ...
report 2018
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Shandilya, N. (author), Ligthart, T. (author), van Voorde, I. (author), Stahlmecke, B. (author), Clavaguera, S. (author), Philippot, C. (author), Goede, H. (author)
The shredding of waste of electrical and electronic equipment (WEEE) and other products, incorporated with nanomaterials, can lead to a substantial release of nanomaterials. Considering the uncertainty, complexity, and scarcity of experimental data on release, we present the development of a Bayesian belief network (BBN) model. This baseline...
article 2018
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Marquart, H. (author), Franken, R. (author), Goede, H. (author), Fransman, W. (author), Schinkel, J. (author)
The ECETOC TRA model (presently version 3.1) is often used to estimate worker inhalation and dermal exposure in regulatory risk assessment. The dermal model in ECETOC TRA has not yet been validated by comparison with independent measured exposure levels. This was the goal of the present study. Measured exposure levels and relevant contextual...
article 2017
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Joustra, S.D. (author), van der Plas, E.M. (author), Goede, J. (author), Oostdijk, W. (author), Delemarre-van de Waal, H.A. (author), Hack, W.W.M. (author), van Buuren, S. (author), Wit, J.M. (author)
Aim Accurate calculations of testicular volume standard deviation (SD) scores are not currently available. We constructed LMS-smoothed age-reference charts for testicular volume in healthy boys. Methods The LMS method was used to calculate reference data, based on testicular volumes from ultrasonography and Prader orchidometer of 769 healthy...
article 2015
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van Deurssen, E. (author), Oude Hengel, K.M. (author), Spaan, S. (author), Goede, H. (author), Meijster, T. (author), Tielemans, E. (author), Heederik, D. (author), Pronk, A. (author)
Objectives: A multidisciplinary intervention study aimed at reducing quartz exposure in the Dutch construction industry was performed. We aimed to assess the effect of the intervention on exposure level and psycho-social and organisational factors. Method: Eight participating construction companies were randomly allocated to an intervention (n =...
article 2014
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van Deurssen, E. (author), Pronk, A. (author), Spaan, S. (author), Goede, H. (author), Tielemans, E. (author), Heederik, D. (author), Meijster, T. (author)
Quartz exposure can cause several respiratory health effects. Although quartz exposure has been described in several observational workplace studies, well-designed intervention studies that investigate the effect of control strategies are lacking. Tis article describes a baseline exposure study that is part of a multidimensional intervention...
article 2014
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Deurssen, E. (author), Oude Hengel, K. (author), Spaan, S. (author), Goede, H. (author), Meijster, T. (author), Tielemans, E. (author), Heederik, D. (author), Pronk, A. (author)
A multidimensional intervention study was performed in order to reduce personal quartz exposure in the Dutch construction industry. The intervention study focused on increasing the use of technical control measures (properly) by targeting organizational and behavioral factors. We aimed to evaluate the effectiveness of the intervention.
public lecture 2014
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Schinkel, J. (author), Richie, P. (author), Goede, H. (author), Fransman, W. (author), van Tongeren, M. (author), Cherrie, J.W. (author), Tielemans, E. (author), Kromhout, H. (author), Warren, N. (author)
This article describes the structure, functionalities, and content of the Advanced REACH Tool (ART) exposure database (version 1.5). The incorporation of the exposure database into ART allows users who do not have their own measurement data for their exposure scenario, to update the exposure estimates produced by the mechanistic model using...
article 2013
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Bongers, W.A. (author), Kasparek, W. (author), Doelman, N.J. (author), van den Braber, R. (author), van den Brand, H. (author), Meo, F. (author), de Baar, M.R. (author), Amerongen, F.J. (author), Donné, A.J.H. (author), Elzendoorn, B.S.Q. (author), Erckmann, V. (author), Goede, A.P.H. (author), Giannone, L. (author), Grünwald, G. (author), Hollman, F. (author), Kaas, G. (author), Krijger, B. (author), Michel, G. (author), Lubyako, L. (author), Monaco, F. (author), Noke, F. (author), Petelin, M. (author), Plaum, B. (author), Purps, F. (author), ten Pierik, J.G.W. (author), Schüller, C. (author), Slob, J.W. (author), Stober, J.K. (author), Schütz, H. (author), Wagner, D. (author), Westerhof, E. (author), Ronden, D.M.S. (author)
A CW capable inline electron cyclotron emission (ECE) separation system for feedback control, featuring oversized corrugated waveguides, is commissioned on ASDEX upgrade (AUG). The system is based on a combination of a polarization independent, non-resonant, Mach-Zehnder diplexer equipped with dielectric plate beam splitters [2, 3] employed as...
conference paper 2012
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Goede, J. (author), Hofman, H.A. (author), Wagenvoort, A.M. (author), Pierik, F.H. (author), Hack, W.W.M. (author)
Background: Testicular microlithiasis (TM) is a relatively uncommon and usually asymptomatic condition that is characterized by multiple 1-3 mm nonshadowing echogenic foci within the parenchyma of the testis. Objectives: The prevalence of testicular microlithiasis was assessed retrospectively in males ranging from 0-18 years who had been...
article 2012
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Goede, J. (author), Hack, W.W.M. (author), Pierik, F.H. (author)
A nine and 13-year-old boy, previously diagnosed with 18q syndrome and an 11q deletion, respectively were diagnosed with testicular microlithiasis (TM). Both cases demonstrate that TM occurs in patients with various chromosomal abnormalities.
article 2012
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Gerritsen-Ebben, R. (author), Glass, R. (author), Goede, H. (author), Schinkel, J. (author), Spaan, S. (author), Charistou, A. (author), Arapaki, N. (author), Machera, K. (author), Kennedy, M. (author), Hart, A. (author)
article 2012
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Marquart, H. (author), Schneider, T. (author), Goede, H. (author), Tischer, M. (author), Schinkel, J. (author), Warren, N. (author), Fransman, W. (author), Spaan, S. (author), van Tongeren, M. (author), Kromhout, H. (author), Tielemans, E. (author), Cherrie, J.W. (author), TNO Kwaliteit van Leven (author)
There is a large variety of activities in workplaces that can lead to emission of substances. Coding systems based on determinants of emission have so far not been developed. In this paper, a system of Activity Classes and Activity Subclasses is proposed for categorizing activities involving chemical use. Activity Classes share their so-called ...
article 2011
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