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Goede, H.A. (author), McNally, K. (author), Gorce, J.P. (author), Marquart, H. (author), Warren, N.D. (author), Fransman, W. (author), Tischer, M. (author), Schinkel, J. (author)
This article describes the development of a mechanistic model for underpinning the dermal Advanced REACH Tool (dART), an extension of the existing ART model and its software platform. It was developed for hand exposure to low volatile liquids (vapour pressure ≤ 10 Pa at 20°C) including solids-in-liquid products. The model is based on an existing...
article 2019
document
McNally, K. (author), Warren, N. (author), Fransman, W. (author), Entink, R.K. (author), Schinkel, J. (author), Van Tongeren, M. (author), Cherrie, J.W. (author), Kromhout, H. (author), Schneider, T. (author), Tielemans, E. (author)
This paper describes a Bayesian model for the assessment of inhalation exposures in an occupational setting; the methodology underpins a freely available web-based application for exposure assessment, the Advanced REACH Tool (ART). The ART is a higher tier exposure tool that combines disparate sources of information within a Bayesian statistical...
article 2014
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Schinkel, J. (author), Richie, P. (author), Goede, H. (author), Fransman, W. (author), van Tongeren, M. (author), Cherrie, J.W. (author), Tielemans, E. (author), Kromhout, H. (author), Warren, N. (author)
This article describes the structure, functionalities, and content of the Advanced REACH Tool (ART) exposure database (version 1.5). The incorporation of the exposure database into ART allows users who do not have their own measurement data for their exposure scenario, to update the exposure estimates produced by the mechanistic model using...
article 2013
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Marquart, H. (author), Schneider, T. (author), Goede, H. (author), Tischer, M. (author), Schinkel, J. (author), Warren, N. (author), Fransman, W. (author), Spaan, S. (author), van Tongeren, M. (author), Kromhout, H. (author), Tielemans, E. (author), Cherrie, J.W. (author), TNO Kwaliteit van Leven (author)
There is a large variety of activities in workplaces that can lead to emission of substances. Coding systems based on determinants of emission have so far not been developed. In this paper, a system of Activity Classes and Activity Subclasses is proposed for categorizing activities involving chemical use. Activity Classes share their so-called ...
article 2011
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Schinkel, J. (author), Warren, N. (author), Fransman, W. (author), van Tongeren, M. (author), McDonnell, P. (author), Voogd, E. (author), Cherrie, J.W. (author), Tischer, M. (author), Kromhout, H. (author), Tielemans, E. (author)
The mechanistic model of the Advanced Reach Tool (ART) provides a relative ranking of exposure levels from different scenarios. The objectives of the calibration described in this paper are threefold: to study whether the mechanistic model scores are accurately ranked in relation to exposure measurements; to enable the mechanistic model to...
article 2011
document
Fransman, W. (author), van Tongeren, M. (author), Cherrie, J.W. (author), Tischer, M. (author), Schneider, T. (author), Schinkel, J. (author), Kromhout, H. (author), Warren, N. (author), Goede, H. (author), Tielemans, E. (author)
This paper describes the development of the mechanistic model within a collaborative project, referred to as the Advanced REACH Tool (ART) project, to develop a tool to model inhalation exposure for workers sharing similar operational conditions across different industries and locations in Europe. The ART mechanistic model is based on a...
article 2011
document
Tielemans, E. (author), Warren, N. (author), Fransman, W. (author), van Tongeren, M. (author), McNally, K. (author), Tischer, M. (author), Ritchie, P. (author), Kromhout, H. (author), Schinkel, J. (author), Schneider, T. (author), Cherrie, J.W. (author), TNO Kwaliteit van Leven (author)
This paper provides an outline of the Advanced REACH Tool (ART) version 1.0 and a discussion of how it could be further developed. ART is a higher tier exposure assessment tool that combines mechanistically modelled inhalation exposure predictions with available exposure data using a Bayesian approach. ART assesses exposure for scenarios across...
article 2011
document
van de Ven, P. (author), Fransman, W. (author), Schinkel, J. (author), Rubingh, C. (author), Warren, N. (author), Tielemans, E. (author), TNO Kwaliteit van Leven (author)
The web-based tool "Stoffenmanager" was initially developed to assist small- and medium-sized enterprises in the Netherlands to make qualitative risk assessments and to provide advice on control at the workplace. The tool uses a mechanistic model to arrive at a "Stoffenmanager score" for exposure. In a recent study it was shown that variability...
article 2010
document
Spaan, S. (author), Fransman, W. (author), Warren, N. (author), Cotton, R. (author), Cocker, J. (author), Tielemans, E. (author), TNO Kwaliteit van Leven (author), KvL (author)
article 2010
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