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Kemmerling, J. (author), Fehlert, E. (author), Kuper, C.F. (author), Rühl-Fehlert, C. (author), Stropp, G. (author), Vogels, J. (author), Krul, C. (author), Vohr, H.W. (author)
Exposure to chemicals may have an influence on the immune system. Often, this is an unwanted effect but in some pharmaceuticals, it is the intended mechanism of action. Immune function tests and in depth histopathological investigations of immune organs were integrated in rodent toxicity studies performed according to an extended OECD test...
article 2015
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Kuper, C.F. (author), Vogels, J. (author), Kemmerling, J. (author), Fehlert, E. (author), Rühl‐Fehlert, C. (author), Vohr, H.W. (author), Krul, C. (author)
Data in a toxicity test are evaluated generally per parameter. Information on the response per animal in addition to per parameter can improve the evaluation of the results. The results from the six studies in rats, described in the paper by Kemmerling, J., Fehlert, E., Rühl-Fehlert, C., Kuper, C.F., Stropp, G., Vogels, J., Krul, C., Vohr, H.-W....
article 2015