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TNO Preventie en Gezondheid (author), Visser, B. (author)
doctoral thesis 2004
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Gaubius instituut TNO (author), Visser, J.T.J. (author)
doctoral thesis 2000
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Koeneman, M.A. (author), Chinapaw, M.J.M. (author), Verheijden, M.W. (author), van Tilburg, T.G. (author), Visser, M. (author), Deeg, D.J.H. (author), Hopman-Rock, M. (author)
Abstract for the International Society for Aging and Physical activity's 8th World Congress on Aging and Physical Activity: A celebration of Diversity and Inclusion in Active Ageing, August 13-17 2012.
conference paper 2012
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Visser, J. (author), Lentjes, E. (author), Haspels, I. (author), Graffelman, W. (author), Blauw, B. (author), de Kloet, R. (author), Nagelkerken, L. (author), TNO Preventie en Gezondheid (author)
Background: In this study we tested the hypothesis that the increased sensitivity to glucocorticoids in chronic fatigue syndrome (CFS)-patients can be attributed to an altered functioning of their glucocorticoid receptors (GR). Methods: For this purpose, affinity and distribution of the GR were studied in purified, peripheral blood mononuclear...
article 2001
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Koeneman, M.A. (author), Chinapaw, M.J.M. (author), Verheijden, M.W. (author), Tilburg, T.G. (author), Visser, M. (author), Deeg, D.J. (author), Hopman-Rock, M. (author)
Background Major life events are associated with a change in daily routine and could thus also affect habitual levels of physical activity. Major life events remain largely unexplored as determinants of older adults' participation in physical activity and sports. This study focused on two major life events, widowhood and retirement, and asked...
article 2012
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Geraedts, E.J. (author), van Dommelen, P. (author), Caliebe, J. (author), Visser, R. (author), Ranke, M.B. (author), van Buuren, S. (author), Wit, J.M. (author), Oostdijk, W. (author)
Background/Aims: Studies on the association between head circumference (HC) and height or weight have shown variable results. Methods: Using data from the Dutch nationwide survey performed in 1997 (n = 14,500), we calculated correlations for different ages, and fitted a regression model for the estimation of HC. HC versus height charts were...
article 2011
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van der Veen, Y.J.J. (author), van Empelen, P. (author), de Zwart, O. (author), Visser, H. (author), Mackenbach, J.P. (author), Richardus, J.H. (author)
article 2014
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Visser, O. (author), Busquet, E.H. (author), van Leeuwen, F.E. (author), Aaronson, N.K. (author), Öry, F.G. (author), TNO Preventie en Gezondheid (author)
Objective. To describe the incidence of cervical cancer in women in North-Holland by country of birth. Design. Descriptive epidemiological study based on data from cancer registries. Method. The number of cases of cervical cancer in North-Holland for the period 1988-1998 was determined using data from the regional cancer registry of the...
article 2003
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Kiesswetter, E. (author), Hengeveld, L.M. (author), Keijser, B.J. (author), Volkert, D. (author), Visser, M. (author)
Objective: Poor oral health might be a modifiable determinant of malnutrition in older age. We aimed to investigate the associations of multiple oral health characteristics with incident malnutrition in community-dwelling older adults. Methods: This exploratory analysis is based on prospective data from 893 participants, aged 55–80 years without...
article 2019
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Visser, J. (author), van Boxel-Dezaire, A. (author), Methorst, D. (author), Brunt, T. (author), de Kloet, E.R. (author), Nagelkerken, L. (author), TNO Preventie en Gezondheid (author)
Antigen-presenting cells are thought to modulate the development of Th1 and Th2 cells by the secretion of interleukin-10 (IL-10) and IL-12. Because glucocorticoids (GC) favor the development of Th2 responses, we determined whether dexamethasone (DEX) and hydrocortisone (HC) have differential effects on lipopolysaccharide-induced IL-10 and IL-12...
article 1998
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van 't Hof, M. (author), Truin, G.J. (author), Kalsbeek, H. (author), Burgersdijk, R. (author), Visser, R.S.H. (author), Heling, G. (author), TNO Preventie en Gezondheid (author)
In 1986 a nationwide dental survey was carried out in the Netherlands. The aims of the study were to assess the prevalence of oral diseases, need and demand for dental care and oral selfcare in the Dutch population aged 15–74 yr. This paper describes the general sampling and analysis procedures to detect selectivity in the participation....
article 1991
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Laman, J.D. (author), Maassen, C.B.M. (author), Schellekens, M.M. (author), Visser, L. (author), Kap, M. (author), de Jong, E. (author), van Puijenbroek, M. (author), van Stipdonk, M.J.B. (author), van Meurs, M. (author), Schwärzler, C. (author), Günthert, U. (author), TNO Preventie en Gezondheid (author)
Interactions between mononuclear cells are required for the formation of inflammatory infiltrates in the CNS and the activation of cellular effector functions provoking demyelination in MS. Membrane-expressed costimulatory molecules are crucial to such interactions. We therefore investigated whether two costimulatory molecules, CD40L (CD154,...
article 1998
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Hanemaaijer, R. (author), Visser, H. (author), Konttinen, Y.T. (author), Koolwijk, P. (author), Verheijen, J.H. (author), Gaubius Instituut TNO (author)
Here we describe a new principle for accessing the activity of the different members of the human matrix-metalloproteinases (MMPs) by a colorimetric assay. Using protein engineering, a modified pro-urokinase was made in which the activation sequence, normally recognized by plasmin (ProArgPheLys ↓ IlelleGlyGly), was replaced by a sequence that is...
article 1998
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Visser, R.S.H. (author), Heling, G.W.J. (author), Burgersdijk, R.C.W. (author), van 't Hof, M.A. (author), Kalsbeek, H. (author), Truin, G.J. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
article 1992
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Hanemaaijer, R. (author), Visser, H. (author), Duffy, J. (author), Verspaget, H.W. (author), Verheijen, J.H. (author), Maguire, T. (author), Gaubius Instituut TNO (author)
Matrix metalloproteinases (MMPs) play an important role in many pathological processes. However, MMP activities are difficult to determine since no simple specific and/or chromogenic substrates exist. Therefore, we have developed a novel MMP activity assay using a modified urokinase as a substrate. In this urokinase, as obtained by protein...
article 1998
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Hanemaaijer, R. (author), Visser, H. (author), Koolwijk, P. (author), Sorsa, T. (author), Salo, T. (author), Golub, L.M. (author), van Hinsbergh, V.W. (author), Gaubius Instituut TNO (author)
Doxycycline is a commonly used broad-spectrum antibiotic. Recently, it has been shown that it also inhibits the activity of mammalian collagenases and gelatinases, an activity unrelated to its antimicrobial efficacy. In this study, we show that doxycycline not only inhibits MMP-8 and MMP-9 (gelatinase B) activity, but also the synthesis of MMPs...
article 1998
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Visser, B. (author), Nielsen, P.K. (author), de Kraker, H. (author), Smits, M. (author), Jensen, B.R. (author), Veeger, D. (author), van Dieën, J.H. (author), TNO Kwaliteit van Leven (author), KvL (author)
The object of the current study was to determine whether static contraction of proximal musculature has an effect on the blood flow more distally in the upper extremity. Static contractions of muscles in the neck shoulder region at three levels (relaxed, shoulders elevated and shoulders elevated loaded with 4.95 kg each) were combined with...
article 2006
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Kiesswetter, E. (author), Keijser, B.J.F. (author), Volkert, D. (author), Visser, M. (author)
Background: To prevent involuntary weight loss in older people, the knowledge about factors affecting body weight (BW) is essential. Therefore, we aimed to investigate the longitudinal associations of multiple oral health aspects with BW in community-dwelling older adults. Methods: This analysis is based on prospective data with a 10-year follow...
article 2020
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Douma, J.H. (author), Visser, B.F. (author), Laros, C.D. (author), Medisch Fysisch Instituut TNO (author)
article 1975
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Visser, R.S.H. (author), Heling, G.W.J. (author), Burgersdijk, R.C.W. (author), van 't Hof, M.A. (author), Kalsbeek, H. (author), Truin, G.J. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
article 1991
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