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document
Briët, E. (author), Broekmans, A.W. (author), Engesser, L. (author), Brommer, E.J.P. (author), Bertina, R.M. (author), Gaubius Instituut TNO (author)
article 1985
document
Briët, E. (author), Engesser, L. (author), Brommer, E.J.P. (author), Broekmans, A.W. (author), Bertina, R.M. (author), Gezondheidsorganisatie TNO Gaubius Instituut TNO (author)
Abstract.
article 1987
document
Nederlands instituut voor praeventieve gezondheidszorg TNO (author), Bleiker, M.A. (author), Broekmans, J.F. (author), Misljenovic, O. (author), Blijker, I.C.F. (author)
report 1991
document
Godschalk, R.W.L. (author), Moonen, E.J.C. (author), Schilderman, A.E.L. (author), Broekmans, W.M.R. (author), Kleinjans, J.C.S. (author), van Schooten, F.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Understanding the kinetics of aromatic-DNA adducts in target tissues and white blood cells (WBC) would enhance the applicability of DNA adducts in WBC as surrogate source of DNA in biomonitoring studies. In the present study, rats were acutely exposed to benzo[a]pyrene (B[a]P; 10 mg/kg body wt) via intratracheal (i.t.), dermal and oral...
article 2000
document
Broekmans, W.M.R. (author), Klöpping-Ketelaars, I.A.A. (author), Schuurman, C.R.W.C. (author), Verhagen, H. (author), van den Berg, H. (author), Kok, F.J. (author), van Poppel, G. (author), TNO Voeding (author)
Observational epidemiologic studies have shown that a high consumption of fruits and vegetables is associated with a decreased risk of chronic diseases. Little is known about the bioavailability of constituents from vegetables and fruits and the effect of these constituents on markers for disease risk. Currently, the recommendation is to...
article 2000
document
Broekmans, W.M.R. (author), Klöpping-Ketelaars, W.A.A. (author), Kluft, C. (author), van den Berg, H. (author), Kok, F.J. (author), van Poppel, G. (author), TNO Voeding (author)
article 2001
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van den Berg, R. (author), van Vliet, T. (author), Broekmans, W.M.R. (author), Cnubben, N.H.P. (author), Vaes, W.H.J. (author), Roza, L. (author), Haenen, G.R.M.M. (author), Bast, A. (author), van den Berg, H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The potential benefits of a high fruit and vegetable intake on the antioxidant status and on relevant biomarkers of oxidative damage to lipids, proteins and DNA and on (functional) markers of oxidative stress were evaluated. A randomized, free living, open placebo-controlled cross-over trial of 3 wk, with a 2-wk washout period between treatments...
article 2001
document
Broekmans, M.A.T.M. (author), Nijland, T.G. (author), Jansen, J.B.H. (author), TNO Bouw (author)
River gravel used as aggregate for concrete in the Netherlands contains several potentially deleterious components with respect to alkali-silica reaction (ASR), viz. porous chert, chalcedony, and impure sandstones (greywackes. mica- and sericite-rich sandstones, siltstones, arkoses etc.). Whereas cherts and chalcedonies are virtually free from...
conference paper 2001
document
Broekmans, W.M.R. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
doctoral thesis 2002
document
Berendschot, T.T.J.M. (author), Broekmans, W.M.R. (author), Klöpping-Ketelaars, I.A.A. (author), Kardinaal, A.F.M. (author), van Poppel, G. (author), van Norren, D. (author), TNO Technische Menskunde (author)
Objective: To investigate whether nutritional factors and possible risk factors for cataract influence the lens optical density (LOD). Design: Three hundred seventy-six subjects, aged 18 to 75 years, were recruited. In a cross-sectional design, serum was analyzed for lutein, zeaxanthin, vitamin C, α-tocopherol, and cholesterol levels. Adipose...
article 2002
document
Broekmans, W.M.R. (author), Berendschot, T.T.J.R. (author), Klöpping-Ketelaars, I.A.A. (author), de Vries, A.J. (author), Goldbohm, R.A. (author), Tijburg, L.B.M. (author), Kardinaal, A.F.M. (author), van Poppel, G. (author), TNO Voeding (author)
Background: Macular pigment (MP), concentrated in the central area of the retina, contains the carotenoids lutein and zeaxanthin. A low MP density could be a risk factor for age-related macular degeneration. Little information is available regarding MP density in relation to serum lutein and zeaxanthin and adipose lutein concentrations in a...
article 2002
document
Broekmans, W.M.R. (author), Klöpping-Ketelaars, I.A.A. (author), Weststrate, J.A. (author), Tijburg, L.B.M. (author), van Poppel, G. (author), Vink, A.A. (author), Berendschot, T.T.J.M. (author), Bots, M.L. (author), Castenmiller, W.A.M. (author), Kardinaal, A.F.M. (author)
Excessive consumption of energy and fat increases the risk for obesity. Snacks containing sucrose polyesters (SPE) as a dietary fat replacer are on the market in the United States. SPE products have been shown to lower concentrations of serum carotenoids in short-term studies. Experimental studies on the longer-term effects on health of...
article 2003
document
Witte, D.R. (author), Broekmans, W.M.R. (author), Kardinaal, A.F.M. (author), Klöpping-Ketelaars, I.A.A. (author), van Poppel, G. (author), Bots, M.L. (author), Kluft, C. (author), Princen, J.M.G. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
Background: Flow mediated dilatation (FMD) of the brachial artery and soluble intercellular adhesion molecule 1 (sICAM-1) are measures of distinct functions of the endothelium, reflecting nitric oxide (NO)-mediated and pro-inflammatory status, respectively. The comparative value of the two measures in relation to cardiovascular risk is unknown....
article 2003
document
Broekmans, W.M.R. (author), Vink, A.A. (author), Boelsma, E. (author), Klöpping-Ketelaars, W.A.A. (author), Tijburg, L.B.M. (author), van 't Veer, P. (author), van Poppel, G. (author), Kardinaal, A.F.M. (author), TNO Voeding (author)
Background: Acute effects of UV irradiation include UV-induced erythema. Sunlight plays an important role in the development of skin cancer. Several predictive factors of UV-induced erythema could also be predictive for skin cancer. Objective: Our objective was to quantitatively assess phenotypical and nutritional determinants of sensitivity to...
article 2003
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