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Fokker, P.A. (author), Borello, E.S. (author), Viberti, D. (author), Verga, F. (author), van Wees, J.D. (author)
Seasonal storage of heat in shallow aquifers for increasing the efficiency of geothermal energy systems requires a proper monitoring strategy. We expanded our earlier work on harmonic pulse testing (HPT) to incorporate the effect of a temperature front moving into the reservoir due to injection of hot (or cold) water. Our analytical solutions...
article 2021
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Schlunk, F. (author), Fisher, P. (author), Princen, H.M.G. (author), Rex, A. (author), Prinz, V. (author), Foddis, M. (author), Lütjohann, D. (author), Laufs, U. (author), Endres, M. (author)
Monoclonal anti-proprotein convertase subtilisin/kexin type 9 (PSCK9) neutralizing antibodies effectively lower plasma cholesterol levels and decrease cardiovascular events but also raised some concern that cognitive function could worsen as a side effect. Here, we performed experiments in mice to characterize the effect of anti-PCSK9 antibodies...
article 2021
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Krone, T. (author), Boessen, R. (author), Bijlsma, S. (author), van Stokkum, R. (author), Clabbers, N.D.S. (author), Pasman, W.J. (author)
Background. N-of-1 designs gain popularity in nutritional research because of the improving technological possibilities, practical applicability and promise of increased accuracy and sensitivity, especially in the field of personalized nutrition. This move asks for a search of applicable statistical methods. Objective. To demonstrate the...
article 2020
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Donker, J. (author), Gavrilova, A. (author), Halstead, M. (author)
Implementing climate and energy targets will require coordinated global action inmany domains, including capacity building, institutional strengthening, and arguably most importantly financing. Transitioning to clean energy will require cumulative investments of trillions of US dollars globally (IEA, 2014, 2017; IFC, 2016; NCE, 2016). Average...
report 2020
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Bongers, C.C.W.G. (author), ten Haaf, D.S.M. (author), Catoire, M. (author), Kersten, B. (author), Wouters, J.A. (author), Eijsvogels, T.M.H. (author), Hopman, M.T.E. (author)
The purpose of this study was to examine the effects of 12 weeks collagen peptide (CP) supplementation on knee pain and function in individuals with self-reported knee pain. Healthy physically active individuals (n = 167, aged 63 [interquartile range = 56-68] years) with self-reported knee pain received 10 g/day of CP or placebo for 12 weeks....
article 2020
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Rehor, I. (author), Maslen, C. (author), Moerman, P.G. (author), van Ravensteijn, B.G.P. (author), van Alst, R. (author), Groenewold, J. (author), Eral, H.B. (author), Kegel, W.K. (author)
Mimicking the locomotive abilities of living organisms on the microscale, where the downsizing of rigid parts and circuitry presents inherent problems, is a complex feat. In nature, many soft-bodied organisms (inchworm, leech) have evolved simple, yet efficient locomotion strategies in which reciprocal actuation cycles synchronize with...
article 2020
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van den Meiracker, J.A. (author), Vermeulen, R.J. (author)
Pollutant emissions of road vehicles have reduced significantly thanks to the development and application of effective and often complex emissions control systems. Tampering of these systems leads to elevated emissions levels comparable to uncontrolled levels of vehicles of decades ago. Therefore, a small share of tampering potentially leads to...
report 2020
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Stationary sensors are carefully distributed throughout the work environment. The concentration of a chemical substance is continuously measured. Modelling tools are used to draw a substance concentration map of the area, making high-concentration zones visible; this allows the location of a source to be identified.
other 2020
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van der Burg, L.R.A. (author), van Kuijk, S.M.J. (author), ter Wee, M.M. (author), Heymans, M.W. (author), de Rijk, A.E. (author), Geuskens, G.A. (author), Ottenheijm, R.P.G. (author), Dinant, G.J. (author), Boonen, A. (author)
Background: Societal expenditures on work-disability benefits is high in most Western countries. As a precursor of long-term work restrictions, long-term sickness absence (LTSA) is under continuous attention of policy makers. Different healthcare professionals can play a role in identification of persons at risk of LTSA but are not well trained....
article 2020
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van Neer, P. (author), Volker, A. (author), Berkhoff, A. (author), Schrama, T. (author), Akkerman, H. (author), van Breemen, A. (author), Peeters, L. (author), van der Steen, J.L. (author), Gelinck, G.H. (author)
Ultrasound based mid-air haptic feedback devices can produce tactile sensations at any time and position without restricting human motion. This is useful for augmented and virtual reality, feedback buttons and virtual user interfaces. The haptic feedback mechanism is caused by acoustic radiation force and streaming. Typical solutions to induce...
conference paper 2020
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Vlasblom, J.L.D. (author), van Gieken, A. (author), Beltman, M. (author), L'Hoir, M.P. (author), Raat, H. (author), Boere-Boonekamp, M.M. (author)
BACKGROUND: Prevention of overweight during early childhood seems promising. OBJECTIVE: To evaluate the effectiveness of the parenting-based BBOFT+ overweight prevention program on child BMI, child health behavior and parenting behavior among 0-36 month old children. BBOFT+ is an acronym for the key healthy lifestyle behaviors that are targeted...
article 2020
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Attema, T. (author)
public lecture 2020
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Verheij, F. (author), Menkveld, M. (author), Usmani, O. (author)
De salderingsregeling levert een positieve bijdrage aan het snelgroeiend aantal huishoudens en eigenaren van utiliteitsgebouwen die investeren in zonnepanelen. Vanwege de kostendalingen van de laatste jaren is er minder stimulering nodig om de investering rendabel te maken. Het kabinet heeft in april 2019 besloten de salderingsregeling vanaf 1...
report 2020
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Argyroudis, S.A. (author), Fotopoulou, S. (author), Karafagka, S. (author), Pitilakis, K. (author), Selva, J. (author), Salzano, E. (author), Basco, A. (author), Crowley, H. (author), Rodrigues, D. (author), Matos, J.P. (author), Schleiss, A.J. (author), Courage, W. (author), Reinders, J. (author), Cheng, Y. (author), Akkar, S. (author), Uckan, E. (author), Erdik, M. (author), Giardini, D. (author), Mignan, A. (author)
Recent natural disasters that seriously affected critical infrastructure (CI) with significant socio-economic losses and impact revealed the need for the development of reliable methodologies for vulnerability and risk assessment. In this paper, a risk-based multi-level stress test method that has been recently proposed, aimed at enhancing...
article 2020
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Remington, B.C. (author), Westerhout, J. (author), Meima, M.Y. (author), Blom, W.M. (author), Kruizinga, A.G. (author), Wheeler, M.W. (author), Taylor, S.L. (author), Houben, G.F. (author), Baumert, J.L. (author)
Food allergy and allergen management are important global public health issues. In 2011, the first iteration of our allergen threshold database (ATDB) was established based on individual NOAELs and LOAELs from oral food challenge in roughly 1750 allergic individuals. Population minimal eliciting dose (EDp) distributions based on this dataset...
article 2020
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Piras, D. (author), van Neer, P.L.M.J. (author), Thijssen, R.M.T. (author), Sadeghian, H. (author)
article 2020
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Bertolo, V.M. (author), Jiang, Q. (author), Walters, C.L. (author), Pupovich, V.A. (author)
One of the main challenges in applying thick-section high-strength steels (HSS) at arctic condition in offshore and maritime industry is to maintain a sufficient level of toughness to prevent brittle failure. An aspect that requires special attention is the through-thickness microstructural variation which may result in different local...
conference paper 2020
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van Groen, B.D. (author), van Duijn, E. (author), de Vries, A. (author), Mooij, M.G. (author), Tibboel, D. (author), Vaes, W.H.J. (author), de Wildt, S.N. (author)
Growth and development affect drug-metabolizing enzyme activity thus could alter the metabolic profile of a drug. Traditional studies to create metabolite profiles and study the routes of excretion are unethical in children due to the high radioactive burden. To overcome this challenge, we aimed to show the feasibility of an absorption,...
article 2020
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van Groen, B.D. (author), Krekels, E.H.J. (author), Mooij, M.G. (author), van Duijn, E. (author), Vaes, W.H.J. (author), Windhorst, A.D. (author), van Rosmalen, J. (author), Hartman, S.J.F. (author), Hendrikse, N.H. (author), Koch, B.C.P. (author), Allegaert, K. (author), Tibboel, D. (author), Knibbe, C.A.J. (author), de Wildt, S.N. (author)
Midazolam is metabolized by the developmentally regulated intestinal and hepatic drug-metabolizing enzyme cytochrome P450 (CYP) 3A4/5. It is frequently administered orally to children, yet knowledge is lacking on the oral bioavailability in term neonates up until 1 year of age. Furthermore, the dispositions of the major metabolites 1-OH...
article 2020
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Landman, A. (author), Groen, E.L. (author), van Paassen, M.M.R. (author), Bronkhorst, A.W. (author), Mulder, M. (author)
Previous studies show that pilots sometimes make roll reversal errors (RREs) when responding to the aircraft bank angle shown on the attitude indicator (AI). This is suggestive of a perceptual ambiguity in the AI. In the current study, we investigated whether expectation contributes to such misperception. Twenty nonpilots performed tasks in a...
article 2020
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