Title
Presence and metabolism of the anabolic steroid boldenone in various animal species: A review
Author
de Brabander, H.F.
Poelmans, S.
Schilt, R.
Stephany, R.W.
le Bizec, B.
Draisci, R.
Sterk, S.S.
van Ginkel, L.A.
Courtheyn, D.
van Hoof, N.
Macrì, A.
de Wasch, K.
TNO Voeding
Publication year
2004
Abstract
The review summarizes current knowledge on the possible illegal use of the anabolic steroid boldenone. The presence of boldenone and metabolites in different animal species and the possibility of the occurrence of endogenous boldenone and metabolites is assessed, as are the methods of analysis used for detection. Different laboratories in the European Union have examined the occurrence of boldenone and its metabolites. The results were discussed at different meetings of a European Commission DG-SANCO Working Party and summarized in an expert report. The situation of the different laboratories at this time is also covered herein. The overall conclusion of the Working Party was that there was a necessity for further research to distinguish between naturally occurring and illegally used boldenone forms. The confirmation of the presence of boldenone metabolites (free and conjugated forms) in certain matrices of animals is proposed as a marker for the illegal treatment with boldenone. © 2004 Taylor & Francis Ltd.
Subject
Biology
Biotechnology
Anabolic steroids
Boldenone
Bovine
Calves
Endogenous
Illegal treatment
Metabolism
Phytosterol
17alpha boldenone
17beta boldenone
anabolic agent
boldenone
clostebol
illicit drug
nandrolone
stanozolol
testosterone
unclassified drug
analytic method
carcinogenicity
chemical structure
conjugation
controlled study
Crustacea
drug use
European Union
feces analysis
female
gas chromatography
human
laboratory test
liquid chromatography
male
mass spectrometry
medical research
microorganism
Mycobacterium
nonhuman
Phycomycetes
priority journal
review
screening test
species difference
steroid metabolism
urinary excretion
Anabolic Agents
Animals
Female
Humans
Male
Substance Abuse Detection
Testosterone
Animalia
Bovinae
To reference this document use:
http://resolver.tudelft.nl/uuid:e41c984b-7112-44e7-97e8-06d900b44ab8
DOI
https://doi.org/10.1080/02652030410001687717
TNO identifier
237774
ISSN
0265-203X
Source
Food Additives and Contaminants, 21 (6), 515-525
Document type
article