Inactivation of high and low molecular weight single-chain urokinase-type plasminogen activator (pro-urokinase) by thrombin in the presence of thrombomodulin

Title

Inactivation of high and low molecular weight single-chain urokinase-type plasminogen activator (pro-urokinase) by thrombin in the presence of thrombomodulin

 Author

de Munk, G.A.W.
Molinari, A.
Rijken, D.C.
Gaubius Laboratory Netherlands Instituut voor verouderings- en vaatziekten onderzoek TNO

Publication year

1993

 Abstract

Chemicals/CAS: amino acid, 65072-01-7; prourokinase, 82657-92-9; thrombin, 9002-04-4; thrombomodulin, 112049-68-0; Enzyme Precursors; Receptors, Cell Surface; Receptors, Thrombin; saruplase, 99149-95-8; Thrombin, EC 3.4.21.5; Urinary Plasminogen Activator, EC 3.4.21.73

 Subject

Health
amino acid
prourokinase
thrombomodulin
amino terminal sequence
comparative study
drug inactivation
letter
molecular weight
protein domain
protein structure
Enzyme Precursors
Molecular Weight
Receptors, Cell Surface
Receptors, Thrombin
Support, Non-U.S. Gov't
Thrombin
Urinary Plasminogen Activator

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 TNO identifier

232133

 ISSN

0340-6245

 Source

Thrombosis and Haemostasis, 69 (1), 88

 Document type

article
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