Title
The impact of preschool wheezing patterns on health-related quality of life at age 4 years pattern of pulmonary adenocarcinoma
Author
Hafkamp-De Groen, E.
Mohangoo, A.D.
Landgraf, J.M.
de Jongste, J.C.
Duijts, L.
Moll, H.A.
Jaddoe, V.W.V.
Hofmane, A.
Raat, H.
Publication year
2013
Abstract
We assessed whether dynamic preschool wheezing patterns affect health-related quality of life (HRQOL) at age 4 years. The study included 3878 children participating a prospective cohort study. Information on preschool wheezing was obtained by questionnaire and children were categorised into: never, early, late and persistent wheezing. At age 4 years HRQOL was measured using the Child Health Questionnaire (CHQ). Persistent wheezing was associated with reduced scores for nine out of 13 CHQ scales. No differences in psychosocial CHQ scores (p>0.05), but lower physical CHQ scores were found in children with late and persistent wheezing, compared to children who never wheezed (p<0.001). Mean scores on general health perceptions were, respectively, eight and 12 points lower (on a 0- 100 scale) in children with late and persistent wheezing (p<0.001), and children with one to three episodes and four or more episodes of wheezing in the fourth year respectively scored seven and 24 points lower (p<0.001), compared to children who never wheezed. Persistent wheezing during preschool age independently affects a child's HRQOL, particularly general health perceptions and physical domains at age 4 years. HRQOL was more affected by frequent wheezing episodes in the fourth year of life, rather than by the duration of wheezing at age 0-4 years.
Subject
Human
CH - Child Health
BSS - Behavioural and Societal Sciences
Healthy for Life
Health
Healthy Living
Asthma symptoms
Child Health Questionnaire-Parent Form 28 items
Preschool children
Well-being
Wheezing
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DOI
https://doi.org/10.1183/09031936.00015712
TNO identifier
471474
ISSN
0903-1936
Source
European Respiratory Journal, 41 (4), 952-959
Document type
article