Title
Type 2 diabetes in children in the Netherlands: The need for diagnostic protocols
Author
Rotteveel, J.
Belksma, E.J.
Renders, C.M.
Hirasing, R.A.
Delemarre-Van de Waal, H.A.
TNO Kwaliteit van Leven
Publication year
2007
Abstract
Objective: The worldwide trend towards obesity in childhood is also observed in the Netherlands and one of the consequences may be type 2 diabetes. In this study, we assessed the number of children with type 2 diabetes, diagnosed by paediatricians, in the Netherlands. Methods: In 2003 and 2004 the Dutch Paediatric Surveillance Unit, a nationwide paediatric register, was used to assess new cases of diabetes mellitus. Data on socio-demographic and clinical characteristics were collected by means of a questionnaire. A second questionnaire was sent to the reporting paediatrician if the diagnosis was inconclusive or if the diagnosis was type 1 diabetes in combination with overweight or obesity, according to international criteria. Results: During the 24 months of registration, the paediatricians reported 1142 new cases of diabetes, 943 of which were eligible for analysis. Initially, 14 patients (1.5%) were reported with type 2 diabetes. Only seven of these patients were classified as type 2 diabetes according to the ADA criteria, as information on C-peptides or antibodies was often missing. Based on clinical characteristics, the other seven patients were very likely to have type 2 diabetes. After the second questionnaire, six more patients met the ADA criteria and two were very likely to have type 2 diabetes. Most of the patients were female (95%), 14% were of Turkish and 18% of Moroccan origin. Conclusion: This study shows a discrepancy between the number of patients with type 2 diabetes diagnosed by paediatricians in daily practice and diagnosed according to the ADA criteria. Moreover, a considerable amount of reported patients were misclassified. Finally, 2.4% patients were classified as (very likely) type 2 diabetes. The development of programmes and protocols for prevention, diagnosis and classification applicable in daily practice is warranted. © 2007 Society of the European Journal of Endocrinology.
Subject
Health
Jeugd en Gezondheid
Morocco
Netherlands
non insulin dependent diabetes mellitus
obesity
pediatrician
priority journal
questionnaire
school child
Turkey (republic)
Adolescent
Body Mass Index
Body Weight
C-Peptide
Child
Child, Preschool
Diabetes Complications
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Female
Humans
Infant
Infant, Newborn
Male
Morocco
Netherlands
Obesity
Population Surveillance
Questionnaires
Sex Factors
Turkey
To reference this document use:
http://resolver.tudelft.nl/uuid:b61f0dff-1838-4dde-8e5a-3a2235b05bde
DOI
https://doi.org/10.1530/eje-06-0754
TNO identifier
240119
ISSN
0804-4643
Source
European Journal of Endocrinology, 157 (2), 175-180
Document type
article