Title
Determination of progesterone by liquid chromatography - mass spectrometry using a moving-belt interface and isotope dilution
Author
Centraal Instituut voor Voedingsonderzoek TNO
van der Greef, J.
Tas, A.C.
Rijk, M.A.H.
ten Noever de Brauw, M.C.
Publication year
1985
Abstract
Progesterone can be determined rapidly and accurately with the method presented, using isotope dilution LC-MS with a moving-belt interface. Deactivation is very useful in that it minimizes belt memory effects and optimizes belt desorption characteristics. Since the moving-belt properties were found to change during time with respect to the parameters mentioned, isotope dilution is of importance in order to obtain accurate results. Chemicals/CAS: progesterone, 57-83-0; Progesterone, 57-83-0.
Subject
Progesterone
Drug analysis
Drug determination
Liquid chromatography
Mass spectrometry
Methodology
Nonhuman
Preliminary communication
Priority journal
Progesterone c 13
Serum
Theoretical study
Chromatography, Liquid
Freeze Drying
Human
Indicator Dilution Techniques
Progesterone
Radioimmunoassay
Spectrum Analysis, Mass
To reference this document use:
http://resolver.tudelft.nl/uuid:aaf41558-b1f1-4040-a84a-73a404448b03
TNO identifier
230006
Source
Journal of Chromatography - Biomedical Applications, 343 (343), 397-401
Document type
article