Print Email Facebook Twitter Intestinal beta-carotene absorption and cleavage in men: Response of beta-carotene and retinyl esters in the triglyceride-rich lipoprotein fraction after a single oral dose of beta-carotene Title Intestinal beta-carotene absorption and cleavage in men: Response of beta-carotene and retinyl esters in the triglyceride-rich lipoprotein fraction after a single oral dose of beta-carotene Author van Vliet, T. Schreurs, W.H.P. van den Berg, H. Centraal Instituut voor Voedingsonderzoek TNO Publication year 1995 Abstract Postprandial response curves of β-carotene and retinyl esters in a triglyceride-rich lipoprotein (TRL) fraction were evaluated as a potential measure of β-carotene uptake and cleavage. β-Carotene, retinyl ester, and triglyceride concentrations in the TRI, fraction (density < 1.006 kg/L) and plasma were measured in 10 men for 8 or 16 h after an oral dose of 15 mg β- carotene. The β-carotene response, unlike the triglyceride and retinyl ester response, can be evaluated in the TRL fraction but not in plasma. Intraindividual variations in the triglyceride-adjusted response of β- carotene and retinyl palmitate in TRL fractions were 23% and 20% and interindividual variations were 42% and 36%, respectively. A low β-carotene response was associated with a high ratio between retinyl palmitate and β- carotene responses (r = -0.56, P = 0.013). In conclusion, the measurement of β-carotene and retinyl esters in the TRL fraction after a dose of β- carotene with a vitamin A-free meal may be an appropriate method to study β- carotene uptake and cleavage Subject Nutritionβ-carotenechylomicronsinterindividual variationintraindividual variationplasmaresponseretinyl esterssecond mealsingle dosetriglyceridesalpha tocopherolarachidic acidbeta carotenelipoproteinretinolretinol esterretinol palmitateretinol stearatesugartriacylglycerolyoghurtadultarticleblood levelclinical articleclinical trialcontrolled clinical trialcontrolled studydietary intakedrug degradationhumanhuman tissueintestine absorptionmaleoral drug administrationtest mealAdministration, OralAdultbeta CaroteneCarotenoidsHumansIntestinal AbsorptionIntestinesLipoproteinsMaleTriglyceridesVitamin A To reference this document use: http://resolver.tudelft.nl/uuid:a88cbc71-5baf-4317-947a-0e97821788fa TNO identifier 82574 Source American Journal of Clinical Nutrition, 62, 110-116 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.