Print Email Facebook Twitter Evidence for a core gut microbiota in the zebrafish Title Evidence for a core gut microbiota in the zebrafish Author Roeselers, G. Mittge, E.K. Stephens, W.Z. Parichy, D.M. Cavanaugh, C.M. Guillemin, K. Rawls, J.F. Publication year 2011 Abstract Experimental analysis of gut microbial communities and their interactions with vertebrate hosts is conducted predominantly in domesticated animals that have been maintained in laboratory facilities for many generations. These animal models are useful for studying coevolved relationships between host and microbiota only if the microbial communities that occur in animals in lab facilities are representative of those that occur in nature. We performed 16S rRNA gene sequence-based comparisons of gut bacterial communities in zebrafish collected recently from their natural habitat and those reared for generations in lab facilities in different geographic locations. Patterns of gut microbiota structure in domesticated zebrafish varied across different lab facilities in correlation with historical connections between those facilities. However, gut microbiota membership in domesticated and recently caught zebrafish was strikingly similar, with a shared core gut microbiota. The zebrafish intestinal habitat therefore selects for specific bacterial taxa despite radical differences in host provenance and domestication status. © 2011 International Society for Microbial Ecology. All rights reserved. Subject LifeMSB - Microbiology and Systems BiologyEELS - Earth, Environmental and Life SciencesBiologybacteriaDanio reriofishgastrointestinal tractmicrobiomepyrosequencing To reference this document use: http://resolver.tudelft.nl/uuid:97d9948e-9802-4dd9-b70f-8bc1d040d346 DOI https://doi.org/10.1038/ismej.2011.38 TNO identifier 435943 ISSN 1751-7362 Source ISME Journal, 5 (10), 1595-1608 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.