Title
Adherence to Growth Hormone Treatment Using a Connected Device in Latin America: Real-World Exploratory Descriptive Analysis Study
Author
Assefi, A.
van Dommelen, P.
Arnaud, L.
Otero, C.
Fernandez-Luque, L.
Koledova, E.
Calliari, L.E.
Publication year
2022
Abstract
Background: Recombinant human growth hormone (rhGH) therapy is an effective treatment for children with growth disorders. However, poor outcomes are often associated with suboptimal adherence to treatment. Objective: The easypod connected injection device records and transmits injection settings and dose data from patients receiving rhGH. In this study, we evaluated adherence to rhGH treatment, and associated growth outcomes, in Latin American patients. Methods: Adherence and growth data from patients aged 2-18 years from 12 Latin American countries were analyzed. Adherence data were available for 6207 patients with 2,449,879 injections, and growth data were available for 497 patients with 2232 measurements. Adherence was categorized, based on milligrams of rhGH injected versus milligrams of rhGH prescribed, as high (≥85%), intermediate (>56%-
Subject
Adherence
Connected device
Growth
Ggrowth disorders
Growth hormone
Electronic injection device
Real-world data
Disorder
Therapy
Treatment
Children
Outcome
To reference this document use:
http://resolver.tudelft.nl/uuid:84e87231-8a70-441c-a17f-50f8e8558c3d
DOI
https://doi.org/10.2196/32626
TNO identifier
970827
Source
JMIR Mhealth and Unhealth, 10 (10), e32626
Document type
article