Title
Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study
Author
TNO Kwaliteit van Leven TNO Voeding
van den Brandt, P.A.
Smits, K.M.
Goldbohm, R.A.
Weijenberg, M.P.
Publication year
2007
Abstract
Energy-adjusted magnesium intake was nonsignificantly inversely related to risk of colorectal cancer (n=2328) in the Netherlands Cohort Study on Diet and Cancer that started in 1986 (n=58 279 men and 62 573 women). Statistically significant inverse trends in risk were observed in overweight subjects for colon and proximal colon cancer across increasing quintiles of magnesium uptake (P-trend, 0.05 and 0.02, respectively). Although an overall protective effect was not afforded, our results suggest an effect of magnesium in overweight subjects, possibly through decreasing insulin resistance. © 2007 Cancer Research.
Subject
Food and Chemical Risk Analysis
BMI
Cohort studies
Colorectal cancer
Adult
Ascending colon
Cancer risk
Cohort analysis
Insulin resistance
Magnesium intake
Major clinical study
Mineral intake
Netherlands
Obesity
Statistical analysis
Statistical significance
Aged
Body Mass Index
Cohort Studies
Colorectal Neoplasms
Female
Humans
Insulin Resistance
Magnesium
Male
Middle Aged
Netherlands
To reference this document use:
http://resolver.tudelft.nl/uuid:79f42d62-1f9f-4bc1-8b4f-7e65c9ff95d2
DOI
https://doi.org/10.1038/sj.bjc.6603577
TNO identifier
239851
ISSN
0007-0920
Source
British Journal of Cancer, 96 (96), 510-513
Document type
article