Differential binding of methyl benzimidazol 2 yl carbamate to fungal tubulin as a mechanism of resistance to this antimiotic agent in mutant strains of Aspergillus nidulans

Title

Differential binding of methyl benzimidazol 2 yl carbamate to fungal tubulin as a mechanism of resistance to this antimiotic agent in mutant strains of Aspergillus nidulans

 Author

Davidse, L.C.
Flach, W.
Centrum voor Plantenfysiologisch Onderzoek Nationale Raad voor Landbouwkundig Onderzoek TNO

Publication year

1977

 Abstract

Chemicals/CAS: benomyl, 17804-35-2; carbon 14, 14762-75-5; colchicine, 64-86-8; fuberidazole, 3878-19-1; griseofulvin, 126-07-8; mebendazole, 31431-39-7; melatonin, 73-31-4; nocodazole, 31430-18-9; parbendazole, 14255-87-9; podophyllotoxin, 518-28-5; tiabendazole, 148-79-8; vinblastine, 865-21-4; Benzimidazoles; Carbamates; Colchicine, 64-86-8; Glycoproteins; Griseofulvin, 126-07-8; Melatonin, 73-31-4; Podophyllotoxin, 518-28-5; Receptors, Drug; Tubulin; Vinblastine, 865-21-4

 Subject

benomyl
carbon 14
colchicine
fuberidazole
mebendazole
nocodazole
r 17 934
radioisotope
tiabendazole
aspergillus nidulans
colchicine h 3
drug binding
drug protein binding
drug resistance
microorganism
mutant
theoretical study
Aspergillus nidulans
Benzimidazoles
Binding, Competitive
Carbamates
Colchicine
Drug Resistance
Glycoproteins
Griseofulvin
Hydrogen-Ion Concentration
Melatonin
Mutation
Podophyllotoxin
Receptors, Drug
Temperature
Tubulin
Vinblastine

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http://resolver.tudelft.nl/uuid:78c78f4c-8d5c-4a80-91d9-8dfab7682fc2

 TNO identifier

280763

 ISSN

0021-9525

 Source

Journal of Cell Biology, 72 (1), 174-193

 Document type

article
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