Title
Effects of Perinatal Exposure to PCBs on Neuropsychological Functions in the Rotterdam Cohort at 9 Years of Age
Author
Vreugdenhil, H.J.I.
Emmen, H.H.
Mulder, P.G.H.
Weisglas-Kuperus, N.
TNO Voeding
Publication year
2004
Abstract
PCBs are known for their neurotoxic properties, especially on the developing brain. To increase insight into the neurotoxic effects of PCB exposure, the authors studied the effects of perinatal exposure to environmental levels of these compounds on different neuropsychological domains. In 9-year-old children of the Rotterdam PCB-dioxin cohort, higher prenatal PCB levels were associated with longer response times (RTs), more variation in RTs, and lower scores on the Tower of London (TOL; Shallice, 1982). A longer breast-feeding duration was associated with lower TOL scores and with better spatial organizational skills. There was some evidence of negative effects of lactational exposure to PCBs on scores on the TOL.
Subject
Health Packaging
Analytical research
polychlorinated biphenyl
article
breast feeding
breast milk
child
cohort analysis
comparative study
controlled study
decision making
drug effect
environmental exposure
female
human
infant
intelligence
lactation
learning
major clinical study
male
Netherlands
neuropsychological test
neuropsychology
neurotoxicity
nonparametric test
pollutant
pregnancy
prenatal exposure
priority journal
psychomotor performance
reaction time
regression analysis
response time
scoring system
short term memory
vision
Breast Feeding
Child
Cohort Studies
Decision Making
Environmental Pollutants
Female
Humans
Intelligence
Male
Maternal Exposure
Memory, Short-Term
Milk, Human
Netherlands
Neuropsychological Tests
Polychlorinated Biphenyls
Pregnancy
Prenatal Exposure Delayed Effects
Psychomotor Performance
Reaction Time
Regression Analysis
Statistics, Nonparametric
Verbal Learning
Visual Perception
To reference this document use:
http://resolver.tudelft.nl/uuid:6d59cfa2-d30c-4ccc-8fd7-aa55def488d5
DOI
https://doi.org/10.1037/0894-4105.18.1.185
TNO identifier
237563
ISSN
0894-4105
Source
Neuropsychology, 18 (1), 185-193
Document type
article