Print Email Facebook Twitter Quality of life and self-esteem in children treated for idiopathic short stature Title Quality of life and self-esteem in children treated for idiopathic short stature Author Theunissen, N.C.M. Kamp, G.A. Koopman, H.M. Zwinderman, K.A.H. Vogels, T. Wit, J.-M. TNO Preventie en Gezondheid Publication year 2002 Abstract Objective: Changes in health-related quality of life (HRQOL) and self-esteem were studied in children with idiopathic short stature (ISS) participating in a study on the effect of growth hormone treatment. Study design: Prepubertal children (n = 36) with ISS were randomly assigned to a treatment or control group. Children with ISS, their parents, and the pediatrician completed HRQOL and self-esteem questionnaires 3 times in 2 years. Results: At the start, children with ISS did not have lower scores than the norm population, except for social functioning HRQOL. The pediatrician reported an improvement of HRQOL in the treatment group, the parents reported no change, and the children in the treatment group reported the same, or sometimes even worse, HRQOL or self-esteem than the control group. Changes related to the child's satisfaction with height and hardly to growth itself. Conclusion: The assumption that growth hormone treatment improves HRQOL in children with ISS could not be supported in this study. Chemicals/CAS: Growth Hormone, 9002-72-6 Subject Human growth hormoneBody growthBody heightChildClinical articleClinical trialControlled clinical trialControlled studyHormonal therapyIdiopathic diseaseMulticenter studyPatient satisfactionQuality of lifeQuestionnaireRandomized controlled trialSelf conceptSelf esteemShort statureSocial adaptationsocial statusAnalysis of VarianceBody HeightChildChild, PreschoolFemaleGrowth HormoneHumansLinear ModelsMaleNetherlandsProspective StudiesQuality of LifeSelf Concept To reference this document use: http://resolver.tudelft.nl/uuid:5507ce37-2ba5-401e-bc00-1f33d64f361b DOI https://doi.org/10.1067/mpd.2002.123766 TNO identifier 280307 ISSN 0022-3476 Source Journal of Pediatrics, 140 (5), 507-515 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.