Title
Quality of life and self-esteem in children treated for idiopathic short stature
Author
Theunissen, N.C.M.
Kamp, G.A.
Koopman, H.M.
Zwinderman, K.A.H.
Vogels, T.
Wit, J.-M.
TNO Preventie en Gezondheid
Publication year
2002
Abstract
Objective: Changes in health-related quality of life (HRQOL) and self-esteem were studied in children with idiopathic short stature (ISS) participating in a study on the effect of growth hormone treatment. Study design: Prepubertal children (n = 36) with ISS were randomly assigned to a treatment or control group. Children with ISS, their parents, and the pediatrician completed HRQOL and self-esteem questionnaires 3 times in 2 years. Results: At the start, children with ISS did not have lower scores than the norm population, except for social functioning HRQOL. The pediatrician reported an improvement of HRQOL in the treatment group, the parents reported no change, and the children in the treatment group reported the same, or sometimes even worse, HRQOL or self-esteem than the control group. Changes related to the child's satisfaction with height and hardly to growth itself. Conclusion: The assumption that growth hormone treatment improves HRQOL in children with ISS could not be supported in this study. Chemicals/CAS: Growth Hormone, 9002-72-6
Subject
Human growth hormone
Body growth
Body height
Child
Clinical article
Clinical trial
Controlled clinical trial
Controlled study
Hormonal therapy
Idiopathic disease
Multicenter study
Patient satisfaction
Quality of life
Questionnaire
Randomized controlled trial
Self concept
Self esteem
Short stature
Social adaptation
social status
Analysis of Variance
Body Height
Child
Child, Preschool
Female
Growth Hormone
Humans
Linear Models
Male
Netherlands
Prospective Studies
Quality of Life
Self Concept
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DOI
https://doi.org/10.1067/mpd.2002.123766
TNO identifier
280307
ISSN
0022-3476
Source
Journal of Pediatrics, 140 (5), 507-515
Document type
article