Title
Aspergillus oryzae in solid-state and submerged fermentations: Progress report on a multi-disciplinary project
Author
te Biesebeke, R.
Ruijter, G.
Rahardjo, Y.S.P.
Hoogschagen, M.J.
Heerikhuisen, M.
Levin, A.
van Driel, K.G.A.
Schutyser, M.A.I.
Dijksterhuis, J.
Zhu, Y.
Weber, F.J.
de Vos, W.M.
van den Hondel, K.A.M.J.J.
Rinzema, A.
Punt, P.J.
Publication year
2002
Abstract
We report the progress of a multi-disciplinary research project on solid-state fermentation (SSF) of the filamentous fungus Aspergillus oryzae. The molecular and physiological aspects of the fungus in submerged fermentation (SmF) and SSF are compared and we observe a number of differences correlated with the different growth conditions. First, the aerial hyphae which occur only in SSFs are mainly responsible for oxygen uptake. Second, SSF is characterised by gradients in temperature, water activity and nutrient concentration, and inside the hyphae different polyols are accumulating. Third, pelleted growth in SmF and mycelial growth in SSF show different gene expression and protein secretion patterns. With this approach we aim to expand our knowledge of mechanisms of fungal growth on solid substrates and to exploit the biotechnological applications. © 2002 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
Subject
Biology
Biotechnology
Amylase
Aspergillus oryzae
Genome-wide expression analysis
Morphology
Polyol
Protease
Solid state
Submerged fermentation
Aspergillus oryzae
conference paper
correlation analysis
fungus growth
fungus hyphae
gene expression
hydrolysis
mycelial growth
nonhuman
oxygen consumption
protein expression
solid state fermentation
temperature dependence
article
biotechnology
fermentation
fungal gene
gene expression regulation
genetics
metabolism
methodology
physiology
Aspergillus
Aspergillus oryzae
Fungi
oxygen
Aspergillus oryzae
Biotechnology
Fermentation
Gene Expression Regulation, Fungal
Genes, Fungal
Hyphae
Oxygen
Oxygen Consumption
To reference this document use:
http://resolver.tudelft.nl/uuid:385178b9-f1b4-49ca-b007-270420723bd4
DOI
https://doi.org/10.1016/s1567-1356(02)00092-2
TNO identifier
236576
ISSN
1567-1356
Source
FEMS Yeast Research, 2 (2), 245-248
Document type
article