Title
CD40-CD40L interactions in atherosclerosis
Author
Laman, J.D.
van Meurs, M.
de Smet, B.J.G.L.
Schoneveld, A.
TNO Preventie en Gezondheid
Publication year
1997
Abstract
The abundant presence of macrophages and activated T cells in atherosclerotic plaques suggests an active involvement of the immune system in this cardiovascular disease. However, insight into cellular interactions inducing relevant effector functions is still limited. Here, Jon Laman and colleagues propose that local interactions between CD40 and CD40 ligand may induce multiple activities by different cell types contributing to atherosclerosis. Chemicals/CAS: Antigens, CD40; CD40 Ligand, 147205-72-9; Ligands; Membrane Glycoproteins
Subject
Health
Cd40 antigen
Glycoprotein gp 39
Atherosclerotic plaque
Immunology
T lymphocyte activation
Animals
Antigens, CD40
Arteriosclerosis
CD40 Ligand
Humans
Ligands
Membrane Glycoproteins
Protein Binding
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http://resolver.tudelft.nl/uuid:fad1f32f-543b-4dd1-8a42-31a1a084b292
TNO identifier
233928
ISSN
0167-5699
Source
Immunology Today, 18 (6), 272-277
Document type
article