Title
Assignment of the human tissue-type plasminogen activator gene (PLAT) to chromosome 8
Author
Verheijen, J.H.
Visse, R.
Wijnen, T.J.
Gaubius Instituut TNO
Publication year
1986
Abstract
Using 1.2kb 3'-terminal Pst-I fragment of a full length tissue-type plasminogen activator (t-PA) cDNA clone (ptPA-8FL) and a set of rodent human somatic cell hydrids, the corresponding human gene PLAT was localized on chromosome 8. Chemicals/CAS: plasminogen activator, 9039-53-6; DNA Restriction Enzymes, EC 3.1.21; DNA, 9007-49-2; Genetic Markers; Tissue Plasminogen Activator, EC 3.4.21.68
Subject
complementary dna
plasminogen activator
blood and hemopoietic system
chromosome 8
gene
gene assignment
gene location
genetic engineering
heredity
hybrid cell
normal human
normal value
Chromosome Mapping
Chromosomes, Human, 6-12 and X
Cloning, Molecular
DNA
DNA Restriction Enzymes
Electrophoresis, Agar Gel
Genetic Markers
Human
Support, Non-U.S. Gov't
Tissue Plasminogen Activator
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TNO identifier
230025
ISSN
0340-6717
Source
Human Genetics, 72 (2), 153-156
Document type
article