Print Email Facebook Twitter Dosimetry for total body irradiation of rhesus monkeys with 300 kV X- rays Title Dosimetry for total body irradiation of rhesus monkeys with 300 kV X- rays Author Zoetelief, J. Wagemaker, G. Broerse, J.J. Centrum voor Stralingsbescherming en Dosimetrie TNO Publication year 1998 Abstract Purpose: To obtain more accurate information on the dose distribution in rhesus monkeys for total body irradiation with orthovoltage X-rays. Materials and methods: Dose measurements were performed with an ionization chamber inside homogeneous cylindrical and rectangular phantoms of various dimensions and in phantoms containing lung-equivalent material. The irradiations were carried out with reference to a monitor ionization chamber placed alongside the phantom or the irradiation cage. Results: Correction factors for mass and lung dose relative to the average close in a homogeneous reference phantom, showed linear relationships with the effective diameter of the monkey. The lung close correction factor relative to the homogeneous phantom was about 1.12 for a 3.5 kg monkey. The stated values for the average absorbed dose in the animal of standard weight should be multiplied by a factor of 0.93 for experiments performed before 1983. All publications on total body irradiations of monkeys at TNO after 1983 contain the corrected dose values. Conclusion: Dose distributions are reported for phantoms of different diameters and of cylindrical or rectangular shape. The new dosimetry has also resulted in a revised statement of the LD50 for the occurrence of bone marrow syndrome after X-irradiation; 4.9 Gy instead of 5.3 Gy. Subject AnimalsBody ConstitutionBody WeightBone MarrowGamma RaysLungMacaca mulattaPolymethyl MethacrylateRadiometryWhole-Body IrradiationX-Rays To reference this document use: http://resolver.tudelft.nl/uuid:eca38cb4-e511-49d9-8e24-040b131e2b64 DOI https://doi.org/10.1080/095530098141654 TNO identifier 234586 ISSN 0955-3002 Source International Journal of Radiation Biology, 74 (2), 265-272 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.