Print Email Facebook Twitter Meat and fat intake and pancreatic cancer risk in the Netherlands Cohort Study Title Meat and fat intake and pancreatic cancer risk in the Netherlands Cohort Study Author Heinen, M.M. Verhage, B.A.J. Goldbohm, R.A. van den Brandt, P.A. TNO Kwaliteit van Leven Publication year 2009 Abstract Meat contains numerous carcinogens, such as heterocyclic amines, polycyclic aromatic hydrocarbons, and N-nitroso compounds, which can be derived either from natural food or during the process of food preparation. These carcinogens may increase pancreatic cancer risk. Furthermore, studies in animals showed that polyunsaturated fatty acids, especially linoleic acid, increase pancreatic cancer risk. We examined prospectively the relation between pancreatic cancer risk and intake of fresh meat, processed meat, fish, eggs, total fat, and different types of fat. The Netherlands Cohort Study consisted of 120,852 men and women who completed a baseline questionnaire in 1986. After 13.3 years of follow-up, 350 pancreatic cancer cases (66% microscopically confirmed) were available for analysis. A validated 150-item food-frequency questionnaire was used to calculate intake of fresh meat, processed meat, fish, eggs, fat and different types of fat. No association was found when examining the association between intake of fresh meat, other types of meat, fish, eggs, dietary intake of total fat and different types of fat and risk of pancreatic cancer. It is important for future studies to investigate the relation between different meat-cooking methods and pancreatic cancer. © 2009 UICC. Subject HealthLeefomgeving en gezondheidCohort studyDietary fatMeatMicroscopic confirmationPancreatic cancercarcinogenheterocyclic aminelinoleic acidnitroso derivativepolycyclic aromatic hydrocarbonpolyunsaturated fatty acidadultagedarticlecancer riskcohort analysiseggfat intakefemalefishfood intakefood processinghumanmajor clinical studymalemeatNetherlandspancreas cancerpriority journalAgedCase-Control StudiesCohort StudiesDietary FatsFemaleHumansMaleMeatMiddle AgedNetherlandsPancreatic NeoplasmsQuestionnairesRisk Factors To reference this document use: http://resolver.tudelft.nl/uuid:de016eaf-7fae-417f-8ced-888ee4c9e824 DOI https://doi.org/10.1002/ijc.24387 TNO identifier 241729 ISSN 0020-7136 Source International Journal of Cancer, 125 (5), 1118-1126 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.