Title
A novel method, COAMATIC® plasmin inhibitor, for the specific determination of Plasmin Inhibitor activity in plasma
Author
Clason, S.B.
Meijer, P.
Kluft, C.
Ersdal, E.
Gaubius Instituut TNO
Publication year
1996
Abstract
A new automated method, COAMATIC® Plasmin Inhibitor, provides a tool for specific determination of Plasmin Inhibitor activity in plasma. The method is adapted to the ACL 300R, Cobas Mira, MLA 1000C and to the Thrombolyzer. Low plasmin concentrations combined with short incubation times ensure good specificity also in the low range, resulting in a value of < 6% when analysing a Plasmin Inhibitor deficient plasma. The method is shown to be insensitive to α2-Macroglobulin. Finally, the COAMATIC Plasmin Inhibitor method shows a promising correlation with the Immediate Plasmin Inhibition Test (IPIT)-method.
Subject
Biology
Antiplasmin
Assay
Conference paper
Fibrinolysis
Human
Plasma
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http://resolver.tudelft.nl/uuid:db5c4f5c-0ea1-40d9-b082-eb25551b4c92
DOI
https://doi.org/10.1016/s0268-9499(96)80078-6
TNO identifier
233513
ISSN
0268-9499
Source
Fibrinolysis, 10 (SUPPL. 2), 165-167
Document type
article