Title
Majority of shrimp-allergic patients are allergic to mealworm
Author
Broekman, H.
Verhoeckx, K.C.
den Hartog Jager, C.F.
Kruizinga, A.G.
Pronk-Kleinjan, M.
Remington, B.C.
Bruijnzeel-Koomen, C.A.
Houben, G.F.
Knulst, A.C.
Publication year
2016
Abstract
The growing world population motivates the exploration of new sustainable protein sources to ensure food security. Insects such as mealworm (Tenebrio molitor) are promising candidates, with active ongoing marketing efforts within America and Europe. This warrants assessment of the potential risks. Toxicologic and microbiological risks were assessed previously,1, 2 but not the potentially allergenic risks. Pilot results3 suggest that shrimp-allergic patients might be at risk for mealworm allergy because IgE binding to tropomyosin and arginine kinase (major shellfish allergens) and sarcoplasmic calcium-binding protein and myosin light chain (minor shell fish allergens) was detected. Our aim was to investigate the allergic potential of mealworm in the shrimp-allergic population. Chemicals / CAS arginine kinase, 9026-70-4; immunoglobulin E, 37341-29-0; tropomyosin, 72067-79-9.
Subject
arginine kinase
calcium binding protein
immunoglobulin E
myosin light chain
tropomyosin
abdominal cramp
allergenicity
allergy rapid test
anaphylaxis
cross reaction
dyspnea
food allergy
food security
house dust allergy
human
insect allergy
Letter
Macrobrachium rosenbergii
mealworm allergy
molecular weight
nausea
nonhuman
Penaeus monodon
pollen allergy
prick test
priority journal
sensitization
shrimp allergy
Tenebrio molitor
urticaria
vomiting
adverse effects
clinical trial
double blind procedure
Food Hypersensitivity
immunology
Adult
Aged
Animals
Double-Blind Method
Female
Food Hypersensitivity
Humans
Male
Middle Aged
Penaeidae
Shellfish
Tenebrio
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DOI
https://doi.org/10.1016/j.jaci.2016.01.005
TNO identifier
954754
ISSN
0091-6749
Source
Journal of Allergy and Clinical Immunology, 137 (137), 1261-1263
Document type
article