Print Email Facebook Twitter Majority of shrimp-allergic patients are allergic to mealworm Title Majority of shrimp-allergic patients are allergic to mealworm Author Broekman, H. Verhoeckx, K.C. den Hartog Jager, C.F. Kruizinga, A.G. Pronk-Kleinjan, M. Remington, B.C. Bruijnzeel-Koomen, C.A. Houben, G.F. Knulst, A.C. Publication year 2016 Abstract The growing world population motivates the exploration of new sustainable protein sources to ensure food security. Insects such as mealworm (Tenebrio molitor) are promising candidates, with active ongoing marketing efforts within America and Europe. This warrants assessment of the potential risks. Toxicologic and microbiological risks were assessed previously,1, 2 but not the potentially allergenic risks. Pilot results3 suggest that shrimp-allergic patients might be at risk for mealworm allergy because IgE binding to tropomyosin and arginine kinase (major shellfish allergens) and sarcoplasmic calcium-binding protein and myosin light chain (minor shell fish allergens) was detected. Our aim was to investigate the allergic potential of mealworm in the shrimp-allergic population. Chemicals / CAS arginine kinase, 9026-70-4; immunoglobulin E, 37341-29-0; tropomyosin, 72067-79-9. Subject arginine kinasecalcium binding proteinimmunoglobulin Emyosin light chaintropomyosinabdominal crampallergenicityallergy rapid testanaphylaxiscross reactiondyspneafood allergyfood securityhouse dust allergyhumaninsect allergyLetterMacrobrachium rosenbergiimealworm allergymolecular weightnauseanonhumanPenaeus monodonpollen allergyprick testpriority journalsensitizationshrimp allergyTenebrio molitorurticariavomitingadverse effectsclinical trialdouble blind procedureFood HypersensitivityimmunologyAdultAgedAnimalsDouble-Blind MethodFemaleFood HypersensitivityHumansMaleMiddle AgedPenaeidaeShellfishTenebrio To reference this document use: http://resolver.tudelft.nl/uuid:d3cc952e-49e4-446e-a8af-e28d7a2a045a DOI https://doi.org/10.1016/j.jaci.2016.01.005 TNO identifier 954754 ISSN 0091-6749 Source Journal of Allergy and Clinical Immunology, 137 (137), 1261-1263 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.