Title
The pro-oxidant chemistry of the natural antioxidants vitamin C, vitamin E, carotenoids and flavonoids
Author
Rietjens, I.M.C.M.
Boersma, M.G.
de Haan, L.
Spenkelink, B.
Awad, H.M.
Cnubben, N.H.P.
van Zanden, J.J.
van der Woude, H.
Alink, G.M.
Koeman, J.H.
Instituut CIVO-Toxicologie en Voeding TNO
Publication year
2002
Abstract
Natural antioxidants like vitamin C, vitamin E, carotenoids, and polyphenols like flavonoids, are at present generally considered to be beneficial components from fruit and vegetables. The anti-oxidative properties of these compounds are often claimed to be responsible for various beneficial health effects of these food ingredients. Together these studies provide the basis for the present rapidly increasing interest for the use of natural antioxidants as functional food ingredients and/or as food supplements. However, at higher doses or under certain conditions antioxidant-type functional food ingredients may exert toxic pro-oxidant activities. The present manuscript gives an overview of especially this pro-oxidative chemistry and toxicity of well-known natural antioxidants including vitamin C, vitamin E, carotenoids and flavonoids. © 2002 Elsevier Science B.V. All rights reserved.
Subject
Environment
To reference this document use:
http://resolver.tudelft.nl/uuid:c87260ac-c307-4108-b212-c1b17684cfe0
DOI
https://doi.org/10.1016/s1382-6689(02)00003-0
TNO identifier
57540
ISSN
1382-6689
Source
Environmental Toxicology and Pharmacology, 11 (3-4), 321-333
Document type
article