Title
Adverse effects of Vinylchloride on fertility and reproduction: a literature study
Author
Instituut CIVO-Toxicologie en Voeding TNO
Koëter, H.B.W.M.
Blijleven, W.G.H.
Dreef-van der Meulen, H.C.
Stijkel, A.
Zielhuis, R.L.
Publication year
1989
Abstract
Both available animal and human data are inadequate for the evaluation of risks with respect to the endocrine system, the reproductive organs and fertility. Limited studies in animals have shown that vinylchloride is not teratogenic or embryotoxic at otherwise non-toxic doses. There are insufficient data with respect to the assessment of a NEAL. Because of the already lowered MAC to 1 ppm after the assessment of carcinogenicity, further studies of effects on reproduction are not considered as opportune.
Subject
Historisch materiaal TNO
Proefdieren
Voortplanting
Vruchtbaarheid
Onvruchtbaarheid
MAC
Maximaal aanvaarde concentratie
Teratogenese
Epidemiologie
Vinylchloride
To reference this document use:
http://resolver.tudelft.nl/uuid:b5587670-fb81-46c5-81a5-14d3dfd57bad
TNO identifier
160905
Report number
Ser. 4, S 73-10
Publisher
Min. SZW, Arbeidsinspectie ; DGA, Den Haag
ISBN
9053070141
ISSN
0921-9218
Series
Studie
Document type
book