Print Email Facebook Twitter Dynamics of red fluorescent dental plaque during experimental gingivitis - A cohort study Title Dynamics of red fluorescent dental plaque during experimental gingivitis - A cohort study Author van der Veen, M.H. Volgenant, C.M.C. Keijser, B. ten Cate, J.M. Crielaard, W. Publication year 2016 Abstract Objectives The dynamics of red fluorescent plaque (RFP) in comparison to clinical plaque and bleeding scores were studied during an experimental gingivitis protocol in a cohort of healthy participants. Methods Forty-one participants were monitored for RFP before (24 h plaque), during 14 days plaque accumulation (days 2, 5, 9, 14) and after 7 days recovery (24 h plaque). RFP was assessed on fluorescence photographs of the vestibular aspect of the anterior teeth (cuspid to cuspid) in the upper and lower jaw. Clinical plaque and bleeding were assessed at days −14, 0, 14 and 21. Results RFP of 24 h plaque was reproducible (days −14, 0), then increased during 14 days plaque accumulation and returned to baseline after 7 days recovery. Groups of low, moderate and high RFP formers were statistically significantly different at all times even already at baseline. The individual RFP response during 14 days plaque accumulation correlated well with RFP of 24 h plaque (days −14, 0). RFP correlated moderate to well with clinical plaque at days −14, 0, 14 and 21. From day 2 of the gingivitis challenge RFP correlated with bleeding at day 14. Conclusions RFP provided an objective measure of oral hygiene status. Given the correlation with clinical parameters found, the amount of RFP after 24 h plaque accumulation was indicatory for the inflammatory response during a prolonged period of no oral hygiene. This trial was registered at the public trial register of the Central Committee on Research Involving Human Subjects (CCMO) under number NL51111.029.14 Subject Clinical studies\trialsDiagnostic systemsImagingOral hygienePlaque\plaque biofilmscohort analysisdiagnostic imaginggrowth, development and agingmouth hygienepathologyperiodontal indexplaque indexproceduresstainingAdolescentAdultBiofilmsCohort StudiesDental PlaqueDental Plaque IndexFemaleGingivitisHumansIncisorMaleMiddle AgedOral HygienePeriodontal IndexProspective StudiesStaining and LabelingYoung AdultLifeMSB - Microbiology and Systems Biology To reference this document use: http://resolver.tudelft.nl/uuid:b538f492-fd2c-40aa-bcbf-73674880cbf6 DOI https://doi.org/10.1016/j.jdent.2016.02.010 TNO identifier 954746 Source Journal of Dentistry, 48 (48), 71-76 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.