Title
Dynamics of red fluorescent dental plaque during experimental gingivitis - A cohort study
Author
van der Veen, M.H.
Volgenant, C.M.C.
Keijser, B.
ten Cate, J.M.
Crielaard, W.
Publication year
2016
Abstract
Objectives The dynamics of red fluorescent plaque (RFP) in comparison to clinical plaque and bleeding scores were studied during an experimental gingivitis protocol in a cohort of healthy participants. Methods Forty-one participants were monitored for RFP before (24 h plaque), during 14 days plaque accumulation (days 2, 5, 9, 14) and after 7 days recovery (24 h plaque). RFP was assessed on fluorescence photographs of the vestibular aspect of the anterior teeth (cuspid to cuspid) in the upper and lower jaw. Clinical plaque and bleeding were assessed at days −14, 0, 14 and 21. Results RFP of 24 h plaque was reproducible (days −14, 0), then increased during 14 days plaque accumulation and returned to baseline after 7 days recovery. Groups of low, moderate and high RFP formers were statistically significantly different at all times even already at baseline. The individual RFP response during 14 days plaque accumulation correlated well with RFP of 24 h plaque (days −14, 0). RFP correlated moderate to well with clinical plaque at days −14, 0, 14 and 21. From day 2 of the gingivitis challenge RFP correlated with bleeding at day 14. Conclusions RFP provided an objective measure of oral hygiene status. Given the correlation with clinical parameters found, the amount of RFP after 24 h plaque accumulation was indicatory for the inflammatory response during a prolonged period of no oral hygiene. This trial was registered at the public trial register of the Central Committee on Research Involving Human Subjects (CCMO) under number NL51111.029.14
Subject
Clinical studies\trials
Diagnostic systems
Imaging
Oral hygiene
Plaque\plaque biofilms
cohort analysis
diagnostic imaging
growth, development and aging
mouth hygiene
pathology
periodontal index
plaque index
procedures
staining
Adolescent
Adult
Biofilms
Cohort Studies
Dental Plaque
Dental Plaque Index
Female
Gingivitis
Humans
Incisor
Male
Middle Aged
Oral Hygiene
Periodontal Index
Prospective Studies
Staining and Labeling
Young Adult
Life
MSB - Microbiology and Systems Biology
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http://resolver.tudelft.nl/uuid:b538f492-fd2c-40aa-bcbf-73674880cbf6
DOI
https://doi.org/10.1016/j.jdent.2016.02.010
TNO identifier
954746
Source
Journal of Dentistry, 48 (48), 71-76
Document type
article