Title
Biomonitoring of exposure to chemical warfare agents
Author
TNO Defensie en Veiligheid
Noort, D.
van der Schans, M.J.
Benschop, H.P.
Contributor
Dishovsky, C. (editor)
Pivovarov, A. (editor)
Benschop, H.P. (editor)
Publication year
2006
Abstract
An overview is presented of the major methods that are presently available for biomonitoring of exposure to chemical warfare agents, i.e., nerve agents and sulfur mustard. These methods can be applied for a variety of purposes such as diagnosis and dosimetry of exposure of casualties, verification of nonadherence to the Chemical Weapon Convention, health surveillance, assessment of low level exposures (Gulf War Syndrome) and last but not least for forensic purposes in case of terrorist attacks with these agents. This paper will focus on methods that are based on the analysis of long-lived protein adducts of CW agents which are detectable weeks or even months after exposure. Examples of real exposure incidents will be described. © 2006 Springer.
Subject
Biomonitoring
Diagnosis
DNA adducts
Immunoassay
Mass spectrometry
Protein adducts
Retrospective detection
Sulfur mustard
To reference this document use:
http://resolver.tudelft.nl/uuid:b4986c0f-0ebd-454e-a2c5-c5e4ad28357a
DOI
https://doi.org/10.1007/1-4020-4170-5_03
TNO identifier
183398
Publisher
Springer, Dordrecht
ISBN
18714641
Source
NATO Security through Science Series A: Chemistry and Biology. Medical treatment of intoxications and decontamination of chemical agents in the area of terrorist attack. Proceedings of the NATO Advanced Research Workshop, Dnepropetrovsk, Ukraine, 25-28 January 2005, 21-26 (Chapter 3)
Document type
bookPart