Print Email Facebook Twitter Higher dietary flavone, flavonol, and catechin intakes are associated with less of an increase in BMI over time in women: A longitudinal analysis from the Netherlands Cohort Study Title Higher dietary flavone, flavonol, and catechin intakes are associated with less of an increase in BMI over time in women: A longitudinal analysis from the Netherlands Cohort Study Author Hughes, L.A.E. Arts, I.C.W. Ambergen, T. Brants, H.A.M. Dagnelie, P.C. Goldbohm, R.A. van den Brandt, P.A. Weijenberg, M.P. TNO Kwaliteit van Leven Publication year 2008 Abstract Background: Dietary flavonoids are suggested to have antiobesity effects. Prospective evidence of an association between flavonoids and body mass index (BMI) is lacking in general populations. Objective: We assessed this association between 3 flavonoid subgroups and BMI over a 14-y period in 4280 men and women aged 55-69 y at baseline from the Netherlands Cohort Study. Design: Dietary intake was estimated at baseline (1986) by a validated food-frequency questionnaire. BMI was ascertained through self-reported height (in 1986) and weight (in 1986, 1992, and 2000). Analyses were based on sex-specific quintiles for the total intake of 6 catechins and of 3 flavonols/flavones. Linear mixed effect modeling was used to assess longitudinal associations in 3 adjusted models: age only, lifestyle (age, energy intake, physical activity, smoking status, alcohol intake, type 2 diabetes, and coffee consumption), and lifestyle and diet (vegetables, fruit, fiber, grains, sugar, dessert, and dieting habits). Results: After adjustment for age and confounders, the BMI(kg/m2) of women with the lowest intake of total flavonols/flavones and total catechins increased by 0.95 and 0.77, respectively, after 14 y. Women with the highest intake of total flavonols/flavones and total catechins experienced a significantly lower increase in BMI of 0.40 and 0.31, respectively (between group difference: P < 0.05). This difference remained after additional adjustment for dietary determinants and after stratification of median baseline BMI. In men, no significant differences in BMI change were observed over the quintiles of flavonoid intake after 14 y. Conclusion: Our results suggest that flavonoid intake may contribute to maintaining body weight in the general female population. © 2008 American Society for Nutrition. Subject AdultBody heightBody massCohort analysisDietary intakeFood frequency questionnaireHuman experimentAge FactorsAgedBody Mass IndexBody WeightCatechinCohort StudiesDietDiet SurveysFemaleFlavonesFlavonolsHumansLife StyleLinear ModelsLongitudinal StudiesMaleMiddle AgedNetherlandsObesityProspective StudiesQuestionnairesSex Factors To reference this document use: http://resolver.tudelft.nl/uuid:b1b55d88-c1de-4cc1-a3ee-5be7deb83ef6 DOI https://doi.org/10.3945/ajcn.2008.26058 TNO identifier 241102 ISSN 0002-9165 Source American Journal of Clinical Nutrition, 88 (5), 1341-1352 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.