Print Email Facebook Twitter Effect of lutein on beta-carotene absorption and cleavage Title Effect of lutein on beta-carotene absorption and cleavage Author van den Berg, H. Centraal Instituut voor Voedingsonderzoek TNO Publication year 1998 Abstract Carotenoid interactions during absorption anti in postabsorptive metabolism have been observed in both human and animal studies. We reviewed the mutual interactions reported between lutein and β-carotene and report new data on the postprandial β-carotene and retinyl ester response in the triglyceride-rich plasma lipoprotein (TRL) fraction in volunteers after a single test meal with β-carotene alone, or β-carotene combined with lutein or lycopene. Results indicate an inhibitory effect of lutein on β-carotene absorption, but apparently not on β-carotene cleavage. In a comparative study with two β-carotene/lutein ratios (2:1 and 1:2, respectively), this inhibitory effect of lutein was found to be most marked when lutein was the predominant carotenoid. In studies on plasma (serum) response also an inhibitory effect of β-carotene on lutein response was observed. Subject Nutritionβ-CaroteneAbsorptionInteractionsLuteinBeta caroteneChylomicronDrug derivativeLipoproteinRetinolRetinol palmitateXanthophyllAbsorptionAnimalBloodConference paperDietDrug interactionHumanMetabolismAbsorptionAnimalsbeta CaroteneChylomicronsDietDrug InteractionsHumansLipoproteinsLuteinVitamin AAnimalia To reference this document use: http://resolver.tudelft.nl/uuid:b10fe470-010f-4643-a5d0-9b8c5dbaf2b6 TNO identifier 234855 ISSN 0300-9831 Source International Journal for Vitamin and Nutrition Research, 68 (6), 360-365 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.