Print Email Facebook Twitter Alcohol consumption and risk of type 2 diabetes among older women Title Alcohol consumption and risk of type 2 diabetes among older women Author Beulens, J.W.J. Stolk, R.P. van der Schouw, Y.T. Grobbee, D.E. Hendriks, H.F.J. Bots, M.L. TNO Kwaliteit van Leven Publication year 2005 Abstract OBJECTIVE - This study aimed to investigate the relation between alcohol consumption and type 2 diabetes among older women. RESEARCH DESIGN AND METHODS - Between 1993 and 1997, 16,330 women aged 49-70 years and free from diabetes were enrolled in one of the Dutch Prospect-EPIC (European Prospective Study Into Cancer and Nutrition) cohorts and followed for 6.2 years (range 0.1-10.1). At enrollment, women filled in questionnaires and blood samples were collected. RESULTS - During follow-up, 760 cases of type 2 diabetes were documented. A linear inverse association (P = 0.007) between alcohol consumption and type 2 diabetes risk was observed, adjusting for potential confounders. Compared with abstainers, the hazard ratio for type 2 diabetes was 0.86 (95% CI 0.66-1.12) for women consuming 5-30 g alcohol per week, 0.66 (0.48-0.91) for 30-70 g per week, 0.91 (0.67-1.24) for 70-140 g per week, 0.64 (0.44-0.93) for 140-210 g per week, and 0.69 (0.47-1.02) for >210 g alcohol per week. Beverage type did not influence this association. Lifetime alcohol consumption was associated with type 2 diabetes in a U-shaped fashion. CONCLUSIONS - Our findings support the evidence of a decreased risk of type 2 diabetes with moderate alcohol consumption and expand this to a population of older women. © 2005 by the American Diabetes Association. Subject HealthBiomedical Researchadultagedalcohol consumptionarticlebeverageblood samplingcontrolled studydisease associationfemalefollow uphazard assessmenthumanmajor clinical studynon insulin dependent diabetes mellitusprospective studyquestionnairebeerblood pressurebody massbody sizeclinical trialdrinking behaviormiddle agedmulticenter studyNetherlandsrisk assessmentsmokingwineAgedAlcohol DrinkingBeerBlood PressureBody Mass IndexBody SizeDiabetes Mellitus, Type 2FemaleHumansMiddle AgedNetherlandsQuestionnairesRisk AssessmentSmokingWine To reference this document use: http://resolver.tudelft.nl/uuid:adf053ff-20f1-453d-8a8a-6dde9bb96fe3 DOI https://doi.org/10.2337/diacare.28.12.2933 TNO identifier 238881 ISSN 0149-5992 Source Diabetes Care, 28 (12), 2933-2938 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.