Title
Hearing loss by week of gestation and birth weight in very preterm neonates
Author
van Dommelen, P.
Verkerk, P.H.
van Straaten, H.L.
Publication year
2015
Abstract
Objective To gain insight into health and related costs associated with very preterm births, one needs accurate information about the prevalence of the disabling conditions, including neonatal hearing loss (NHL). Study design We assessed the prevalence of NHL by week of gestation and categories of birth weight in very preterm neonates. Results of the 2-stage Automated Auditory Brainstem Response nationwide Newborn Hearing Screening Program in Dutch Neonatal Intensive Care Units and diagnostic examinations were centrally registered between October 1998 and December 2012 and included in this study. NHL was defined as impaired when the neonate conventional Auditory Brainstem Response level exceeded 35 dB near Hearing Level at diagnostic examination. Birth weight was stratified into <750 g, 750-999 g, 1000-1249 g, 1250-1499 g, and ≥1500 g, and by small for gestational age (SGA; <10th percentile) vs appropriate for gestational age. Logistic regression analyses and recursive partitioning were performed. Results In total, 18 564 very preterm neonates were eligible. The prevalence of NHL consistently increased with decreasing week of gestation (1.2%-7.5% from 31 to 24 weeks) and decreasing birth weight (1.4%-4.8% from ≥1500 g to <750 g, all P < .002). Most vulnerable to NHL were girls <28 weeks, boys <30 weeks, and SGA neonates. The SGA effect started at 27 weeks. Conclusions Gestational age and birth weight quantify the risk of NHL. This information can be used at the individual level for parent counseling and at the population level for medical decision making.
Subject
Life
LS - Life Style CH - Child Health
ELSS - Earth, Life and Social Sciences
Healthy for Life
Health
Healthy Living
Automated auditory brainstem response
Appropriate for gestational age
Gestational age
Hearing loss
Neurodevelopmental impairment
Neonatal hearing loss
Newborn Hearing Screening Program
Neonatal intensive care unit
Small for gestational age
Auditory screening
Birth weight
Diagnostic test accuracy study
Disabled person
Evoked brain stem auditory response
Female
Gestation period
Health care cost
Hearing impairment
High risk population
Human
Major clinical study
Male
Newborn
Newborn disease
Newborn intensive care
Newborn screening
Premature labor
Prematurity
Prevalence
Small for date infant
Very low birth weight
Vulnerable population
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http://resolver.tudelft.nl/uuid:aa76e448-f8a1-4c0a-873b-ad45a61efee7
DOI
https://doi.org/10.1016/j.jpeds.2014.12.041
TNO identifier
525728
Source
Journal of Pediatrics, 166 (4), 840-843
Document type
article