Title
Experimental estimation of migration and transfer of organic substances from consumer articles to cotton wipes: Evaluation of underlying mechanisms
Author
Clausen, P.A.
Spaan, S.
Brouwer, D.H.
Marquart, H.
le Feber, M.
Engel, R.
Geerts, L.
Jensen, K.A.
Kofoed-Sørensen, V.
Hansen, B.
de Brouwere, K.
Publication year
2016
Abstract
The aim of this work was to identify the key mechanisms governing transport of organic chemical substances from consumer articles to cotton wipes. The results were used to establish a mechanistic model to improve assessment of dermal contact exposure. Four types of PVC flooring, 10 types of textiles and one type of inkjet printed paper were used to establish the mechanisms and model. Kinetic extraction studies in methanol demonstrated existence of matrix diffusion and indicated the presence of a substance surface layer on some articles. Consequently, the proposed substance transfer model considers mechanical transport from a surface film and matrix diffusion in an article with a known initial total substance concentration. The estimated chemical substance transfer values to cotton wipes were comparable to the literature data (relative transfer ∼2%), whereas relative transfer efficiencies from spiked substrates were high (∼50%). For consumer articles, high correlation (r 2 =0.92) was observed between predicted and measured transfer efficiencies, but concentrations were overpredicted by a factor of 10. Adjusting the relative transfer from about 50% used in the model to about 2.5% removed overprediction. Further studies are required to confirm the model for generic use. © 2016 Nature America, Inc. All rights reserved.
Subject
Life
RAPID - Risk Analysis for Products in Development
ELSS - Earth, Life and Social Sciences
Biomedical Innovation
Biology
Healthy Living
Dermal exposure
Exposure modeling
Phthalates
Volatile organic compounds
To reference this document use:
http://resolver.tudelft.nl/uuid:9dd7e6c4-2d5d-4b34-8ca3-74a8b8f071ad
DOI
https://doi.org/10.1038/jes.2015.35
TNO identifier
531077
ISSN
1559-0631
Source
Journal of Exposure Science and Environmental Epidemiology, 26 (1), 104-112
Document type
article