Title
Exposure to fungicides in fruit growing: Re-entry time as a predictor for dermal exposure
Author
Tielemans, E.
Louwerse, E.
de Cock, J.
Brouwer, D.
Zielhuis, G.
Heederik, D.
Centraal Instituut voor Voedingsonderzoek TNO
Publication year
1999
Abstract
As part of a European Concerted Action on Male Reproduction Capability an exposure assessment survey was conducted among seasonal workers in the fruit growing sector in the Netherlands. Dermal exposure to the fungicides captan and tolylfluanid was measured using cotton gloves (12 persons) and skin pads on several body parts (12 persons). In addition, a set of exposure data was used from a study conducted recently among Dutch fruit growers. For harvesting activities, re-entry time appeared to be an important determinant of dermal exposure to captan and tolylfluanid. Explained variance of regression models was moderate to high (range 0.30-0.87). For captan, calculated half-life times from the most recent exposure survey were lower (glove data: 5 days; pad data: 6 days) compared with half-life times based on the previously conducted study (11 days). Possible explanations for the discrepancy are discussed. For tolylfluanid, estimated half-life times during harvesting were 2 and 3 days, based on pad and glove data, respectively. Prediction of captan exposure during other crop activities appeared to be far more difficult (explained variance equal to 0.06), although the estimated half-life time was comparable with that for harvesting. The data suggest that re-entry time gives useful information to group workers in broad exposure categories. Nonetheless, it was concluded that large studies are needed to evaluate the importance of re-entry time in more detail.
Subject
Nutrition
Epidemiology
Exposure assessment
Fungicides
Captan
Fungicide
Agricultural worker
Clinical article
Glove
Half life time
High performance liquid chromatography
Human
Occupational exposure
Prediction
Skin
Time
Agricultural Workers' Diseases
Aniline Compounds
Chromatography, High Pressure Liquid
Dermatitis, Occupational
Fruit
Fungicides, Industrial
Humans
Male
Netherlands
Occupational Exposure
Pilot Projects
Predictive Value of Tests
Regression Analysis
Seasons
Sulfonamides
Time Factors
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TNO identifier
235211
ISSN
0002-8894
Source
American Industrial Hygiene Association Journal, 60 (6), 789-793
Document type
article