Title
Determinants of bone mass and bone geometry in adolescent and young adult women
Author
Kardinaal, A.F.M.
Hoorneman, G.
Väänänen, K.
Charles, P.
Ando, S.
Maggiolini, M.
Charzewska, J.
Rotily, M.
Deloraine, A.
Heikkinen, J.
Juvin, R.
Schaafsma, G.
Centraal Instituut voor Voedingsonderzoek TNO
Publication year
2000
Abstract
Bone mass and bone geometry are considered to have independent effects on bone strength. The purpose of this study was to obtain data on bone mass and geometry in young female populations and how they are influenced by body size and lifestyle factors. In a cross-sectional, observational study in six European countries, 1116 healthy Caucasian girls aged 11-15 and 526 women aged 20-23 participated. Their radius was scanned at the ultradistal site and at a site approximately 30% of the radius length from the distal end with dual energy X-ray absorptiometry (DXA). The following parameters were assessed from the scans: bone mineral content (BMC), bone mineral density (BMD), cortical wall thickness (CWT), middistal diameter (D), cortical index (CI = 2CWT/D), and the Breaking Bending Resistance Index (BBRI = (D4 - [D- CWT]4/D). Calcium intake was assessed by 3-day food records and physical activity by questionnaire. Body size parameters were measured by anthropometry. All parameters showed an increasing trend with pubertal stage and age, except for physical activity and calcium intake. BMC and BMD were relatively more dependent on body weight and age at menarche, whereas variation in D and the mechanical index BBRI was better explained by differences in height and grip strength. CI and CWT were relatively independent of variation in body size, whereas BMC and BBRI especially were explained for a substantial proportion (25-33% in the young adults) by body size parameters. Dietary intake of calcium and level of physical activity seem to contribute little to variation in bone parameters. Chemicals/CAS: Calcium, Dietary
Subject
Body size
Bone mineral density
Cortical wall thickness
Dual-energy X-ray absorptiometry
Grip strength
Calcium
Adolescence
Adolescent
Adult
Age
Anthropometry
Body size
Body weight
Bone bowing
Bone density
Bone mass
Bone mineral
Bone strength
Bone structure
Calcium intake
Caucasian
Dual energy X ray absorptiometry
Europe
Female
Grip strength
Height
Human
Human experiment
Lifestyle
Mechanical stress
Menarche
Normal human
Physical activity
Priority journal
Puberty
Questionnaire
Radius
School child
Adolescent
Adult
Age Factors
Body Constitution
Body Height
Body Weight
Bone and Bones
Bone Density
Calcium, Dietary
Child
Cross-Sectional Studies
Europe
European Continental Ancestry Group
Female
Humans
Life Style
Menarche
To reference this document use:
http://resolver.tudelft.nl/uuid:9acf5cc1-0521-492c-a808-d69ee3622539
TNO identifier
56521
ISSN
0171-967X
Source
Calcified Tissue International, 66 (2), 81-89
Document type
article