Title
Evidence for a core gut microbiota in the zebrafish
Author
Roeselers, G.
Mittge, E.K.
Stephens, W.Z.
Parichy, D.M.
Cavanaugh, C.M.
Guillemin, K.
Rawls, J.F.
Publication year
2011
Abstract
Experimental analysis of gut microbial communities and their interactions with vertebrate hosts is conducted predominantly in domesticated animals that have been maintained in laboratory facilities for many generations. These animal models are useful for studying coevolved relationships between host and microbiota only if the microbial communities that occur in animals in lab facilities are representative of those that occur in nature. We performed 16S rRNA gene sequence-based comparisons of gut bacterial communities in zebrafish collected recently from their natural habitat and those reared for generations in lab facilities in different geographic locations. Patterns of gut microbiota structure in domesticated zebrafish varied across different lab facilities in correlation with historical connections between those facilities. However, gut microbiota membership in domesticated and recently caught zebrafish was strikingly similar, with a shared core gut microbiota. The zebrafish intestinal habitat therefore selects for specific bacterial taxa despite radical differences in host provenance and domestication status. © 2011 International Society for Microbial Ecology. All rights reserved.
Subject
Life
MSB - Microbiology and Systems Biology
EELS - Earth, Environmental and Life Sciences
Biology
bacteria
Danio rerio
fish
gastrointestinal tract
microbiome
pyrosequencing
To reference this document use:
http://resolver.tudelft.nl/uuid:97d9948e-9802-4dd9-b70f-8bc1d040d346
DOI
https://doi.org/10.1038/ismej.2011.38
TNO identifier
435943
ISSN
1751-7362
Source
ISME Journal, 5 (10), 1595-1608
Document type
article