Title
The human gut microbiome diet and health Post hoc non ergo propter hoc
Author
Roeselers, G.
Bouwman, J.
Levin, E.
Publication year
2016
Abstract
The gastro-intestinal microbiome has become the subject of intensive research, which is beginning to elucidate its roles in human health. It is becoming increasingly recognised that gut microbiota plays a part in regulating human immune homeostasis and metabolism, which gives rise to novel opportunities for preventative and treatment strategies. The key challenge in this field is the ability to define causality in the relationship between nutrition, microbiota and host health. In this commentary we argue for an increased focus on cause-and-effect relationships within studies that relate to the human microbiome in health and predispositions to disease. With the right experimental models, data accessibility infrastructure and advanced machine learning tools, causal relationships among components of complex host-microbiome systems can be elucidated. © 2016 Elsevier Ltd
Subject
Causation
Gut microbiome
Machine learning
Metagenomics
Models
Nutrition
Learning systems
Machine learning
Models
Causal relationships
Causation
Cause-and-effect relationships
Data accessibility
Experimental models
Intensive research
Metagenomics
Microbiome
Nutrition
Life
MSB - Microbiology and Systems Biology
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DOI
https://doi.org/10.1016/j.tifs.2016.08.010
TNO identifier
954708
ISSN
0924-2244
Source
Trends in Food Science and Technology, 57 (57), 302-305
Document type
article