Title
A continuous in vitro method for estimation of the bioavailability of minerals and trace elements in foods: application to breads varying in phytic acid content
Author
Centraal Instituut voor Voedingsonderzoek TNO
Wolters, M.G.E.
Schreuder, H.A.W.
van den Heuvel, G.
van Lonkhuijsen, H.J.
Hermus, R.J.J.
Voragen, A.G.J.
Publication year
1993
Abstract
A continuous in vitro method for the estimation of the bioavailability of minerals and trace elements is presented. This in vitro method is believed to be more representative of in vivo physiological conditions than in vitro methods based on equilibrium dialysis, because dialysable components are continuously removed from the pancreatic digestion mixture. The continuous in vitro method is compared with the equilibrium in vitro method with respect to the dialysability of Ca, Mg, Fe, Cu and Zn from eight different types of bread (varying in phytic acid content). The results show a pronounced effect of continuous removal of dialysable components from the pancreatic digestion mixture on the dialysability of minerals and trace elements. Furthermore, removal of dialysable components influences the effect of phytic acid on the bioavailability of minerals and trace elements. For these two reasons the importance of removal of dialysable components in vitro for the estimation of bioavailability in vivo needs further investigation. The bioavailability of minerals and trace elements from bread samples is not related to the phytic acid content only. Therefore, the effect of phytic acid on the bioavailability of minerals and trace elements cannot be studied separately from the effects of other components on bioavailability. Chemicals/CAS: calcium, 7440-70-2; copper, 15158-11-9, 7440-50-8; iron, 14093-02-8, 53858-86-9, 7439-89-6; magnesium, 7439-95-4; phytic acid, 83-86-3; zinc, 7440-66-6; Minerals; Phytic Acid, 83-86-3; Trace Elements
Subject
Production
Technology
FoodBiology
Biochemistry
Medicine
Geneeskunde
Physiology
Fysiologie
Bread
Comparative Study
Dialysis
Digestion
Hydrogen-Ion Concentration
Minerals
Nutritive Value
Phytic Acid
Trace Elements
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TNO identifier
80258
ISSN
0007-1145
Source
British Journal of Nutrition, 69 (69), 849-861
Document type
article