Print Email Facebook Twitter European birth cohorts for environmental health research Title European birth cohorts for environmental health research Author Vrijheid, M. Casas, M. Bergström, A. Carmichael, A. Cordier, S. Eggesbø, M. Eller, E. Fantini, M.P. Fernández, M.F. Fernández-Somoano, A. Gehring, U. Grazuleviciene, R. Hohmann, C. Karvonen, A.M. Keil, T. Kogevinas, M. Koppen, G. Krämer, U. Kuehni, C.E. Magnus, P. Majewska, R. Andersen, A.-M.N. Patelarou, E. Petersen, M.S. Pierik, F.H. Polanska, K. Porta, D. Richiardi, L. Santos, A.C. Slama, R. Sram, R.J. Thijs, C. Tischer, C. Toft, G. Trnovec, T. Vandentorren, S. Vrijkotte, T.G.M. Wilhelm, M. Wright, J. Nieuwenhuijsen, M. Publication year 2012 Abstract Background: Many pregnancy and birth cohort studies investigate the health effects of early-life environmental contaminant exposure. An overview of existing studies and their data is needed to improve collaboration, harmonization, and future project planning. Objectives: Our goal was to create a comprehensive overview of European birth cohorts with environmental exposure data. Methods: Birth cohort studies were included if they a) collected data on at least one environmental exposure, b) started enrollment during pregnancy or at birth, c) included at least one follow-up point after birth, d) included at least 200 mother-child pairs, and e) were based in a European country. A questionnaire collected information on basic protocol details and exposure and health outcome assessments, including specific contaminants, methods and samples, timing, and number of subjects. A full inventory can be searched on www.birthcohortsenrieco.net. Results: Questionnaires were completed by 37 cohort studies of > 350,000 mother-child pairs in 19 European countries. Only three cohorts did not participate. All cohorts collected biological specimens of children or parents. Many cohorts collected information on passive smoking (n = 36), maternal occupation (n = 33), outdoor air pollution (n = 27), and allergens/biological organisms (n = 27). Fewer cohorts (n = 12-19) collected information on water contamination, ionizing or nonionizing radiation exposures, noise, metals, persistent organic pollutants, or other pollutants. All cohorts have information on birth outcomes; nearly all on asthma, allergies, childhood growth and obesity; and 26 collected information on child neurodevelopment. Conclusion: Combining forces in this field will yield more efficient and conclusive studies and ultimately improve causal inference. This impressive resource of existing birth cohort data could form the basis for longer-term and worldwide coordination of research on environment and child health. Subject Earth & EnvironmentUES - Urban Environment & SafetyEELS - Earth, Environmental and Life SciencesEnvironmentEnergy / Geological Survey NetherlandsBirth cohortsChild healthEnvironmental exposuresEuropeReview To reference this document use: http://resolver.tudelft.nl/uuid:91d936ff-054a-4116-809e-2df727a84ce6 DOI https://doi.org/10.1289/ehp.1103823 TNO identifier 445987 ISSN 0091-6765 Source Environmental Health Perspectives, 120 (1), 29-37 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.