Real-time MALDI for TOF MS analysis of biological aerosols and contaminated paper dust with the BioSparQ™ detector
conference paper
A bioaerosol detector based upon single particle MALDI TOF MS, BiosparQ™, is described. The functioning of the system is illustrated by an example for a civil and a military context. In the civil context a particulate paper sample, spiked with Bacillus atropheus spores, is successfully analysed. The paper sample is a representative sample for dust collected at post sorting machines.
In a military context a demonstrator of the system is evaluated in a bio-aerosol test chamber. In the chamber the detector is exposed to the type of challenges as can be expected in realistic field trials. The result show the single particle approach offers the possibility to detect biological agents in a complex biological background.
In a military context a demonstrator of the system is evaluated in a bio-aerosol test chamber. In the chamber the detector is exposed to the type of challenges as can be expected in realistic field trials. The result show the single particle approach offers the possibility to detect biological agents in a complex biological background.
TNO Identifier
360771
Source title
10th International Symposium on Protection against Chemical and Biological Warfare Agents, Stockholm, Sweden, 8-11 June 2010
Pages
6
Files
To receive the publication files, please send an e-mail request to TNO Repository.